Opportunity Information: Apply for W81XWH 11 OCRP TPA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Ovarian Cancer Translational Pilot Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Apr 20, 2011 and posted on Apr 20, 2011.
  • Applicants must submit their applications by Aug 18, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,880,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 9 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DoD Ovarian Cancer Translational Pilot Award is a U.S. Department of Defense funding opportunity designed to back early-stage translational research projects in ovarian cancer that can move promising ideas closer to real-world clinical use. The emphasis is on practical translation rather than basic science alone: projects should either push an insight from the laboratory toward patient care (bench to bedside) or take a clinically observed problem back into the lab for focused investigation (bedside to bench). The overall intent is to speed up progress on a clearly defined, important ovarian cancer question by funding pilot work that can serve as a catalyst for larger follow-on studies and eventual clinical application.

A central theme of the award is innovation that meaningfully challenges or expands how ovarian cancer is currently understood, prevented, detected, or treated. The program is looking for proposals that do more than refine established approaches; it wants ideas that could shift thinking or open new avenues, while still being grounded in a plausible translational path. The pilot nature of the mechanism means the work is expected to generate strong preliminary evidence, feasibility data, or proof-of-concept results that make the next step toward clinical testing or implementation more realistic.

The opportunity explicitly recognizes that translational ideas can come from many sources, not just laboratory breakthroughs. Investigators may base a pilot project on a new lab discovery, a careful synthesis of existing literature that reveals a promising gap or opportunity, population-based or epidemiologic findings, novel signals emerging from clinical trials, or a clinician's direct experience with patients including patterns and observations that have not yet been formally studied. This broad view of where valuable translational questions originate is meant to capture clinically relevant problems and opportunities that might otherwise be missed.

Administratively, the award was offered as a discretionary funding opportunity through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under Funding Opportunity Number W81XWH-11-OCRP-TPA. It supported grants and cooperative agreements within the science and technology/research and development category. The program anticipated making about 9 awards, with an estimated total funding pool of $2,880,000. The CFDA number associated with the program was 12.420 (Military Medical Research and Development). There was no cost sharing or matching requirement, and eligibility was listed as unrestricted, meaning it was generally open to any type of applicant entity unless additional eligibility clarifications in the full announcement stated otherwise.

Key dates for this opportunity were a posting/creation date of April 20, 2011, an original and current closing date of August 18, 2011, and an archive date of September 17, 2011. For applicants who had trouble accessing the full announcement electronically, the listed support contact was the CDMRP Help Desk at 301-682-5507.

FAQs: DoD Ovarian Cancer Translational Pilot Award

What is the DoD Ovarian Cancer Translational Pilot Award?

The DoD Ovarian Cancer Translational Pilot Award is a U.S. Department of Defense funding opportunity intended to support early-stage translational research in ovarian cancer. The focus is on pilot projects that move promising ideas closer to real-world clinical use.

What kind of research does this award emphasize?

This opportunity emphasizes translational research rather than basic science alone. Projects are expected to have a practical path toward clinical application and to accelerate progress on a clearly defined ovarian cancer question through pilot work.

What does "translational" mean in the context of this award?

In this program, translational research includes both:

  • Bench to bedside: advancing a laboratory insight toward patient care and clinical use
  • Bedside to bench: taking a clinically observed problem back into the lab for focused investigation

Is the award intended for large, long-term projects?

No. This is a pilot mechanism intended to fund early-stage translational work. The expectation is that the project generates feasibility data, preliminary evidence, or proof-of-concept results that can catalyze larger follow-on studies and eventual clinical application.

How innovative does a proposal need to be?

The award places a strong emphasis on innovation that meaningfully challenges or expands how ovarian cancer is understood, prevented, detected, or treated. It is looking for proposals that go beyond refining established approaches and instead could shift thinking or open new avenues, while still being grounded in a plausible translational path.

What are the expected outcomes of a funded pilot project?

The program expects projects to produce strong preliminary evidence, feasibility data, and/or proof-of-concept results that make the next step toward clinical testing or implementation more realistic.

Where can translational ideas come from for this award?

The opportunity recognizes that translational ideas may originate from many sources, including:

  • New laboratory discoveries
  • Careful synthesis of existing literature that identifies a promising gap or opportunity
  • Population-based or epidemiologic findings
  • Novel signals emerging from clinical trials
  • Clinician experience with patients, including patterns and observations not yet formally studied

Which government organization administered this opportunity?

The award was offered as a discretionary funding opportunity through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the Funding Opportunity Number (FON) for this program?

The Funding Opportunity Number listed for this opportunity is W81XWH-11-OCRP-TPA.

What type of funding instruments were supported?

The opportunity supported grants and cooperative agreements within the science and technology/research and development category.

How many awards were anticipated?

The program anticipated making about 9 awards.

What was the estimated total funding available?

The estimated total funding pool was $2,880,000.

Is there a CFDA number associated with this program?

Yes. The CFDA number associated with the program is 12.420 (Military Medical Research and Development).

Was cost sharing or matching required?

No. The opportunity indicated there was no cost sharing or matching requirement.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning it was generally open to any type of applicant entity unless additional eligibility clarifications in the full announcement stated otherwise.

When was the opportunity posted?

The posting/creation date was April 20, 2011.

What was the application closing date?

The original and current closing date was August 18, 2011.

When was the opportunity archived?

The archive date was September 17, 2011.

What should applicants do if they could not access the full announcement electronically?

Applicants who had trouble accessing the full announcement electronically were directed to contact the CDMRP Help Desk at 301-682-5507.

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