Opportunity Information: Apply for W81XWH 14 PRARP QUAL

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Alzheimers Quality of Life Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Sep 11, 2014 and posted on Sep 11, 2014.
  • Applicants must submit their applications by Jan 14, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,600,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 14 PRARP QUAL

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Opportunity Summary:

The DoD Peer Reviewed Alzheimers Quality of Life Research Award (FY14 PRARP QUAL) is a Department of the Army funding opportunity administered through the Congressionally Directed Medical Research Programs (CDMRP) that supports research aimed at easing day-to-day impacts experienced by people affected by overlapping symptoms seen in both traumatic brain injury (TBI) and Alzheimers disease (AD). The central goal is practical: reduce the burden on affected individuals and on the people who care for them, with a particular emphasis on needs within the military community where TBI exposure and long-term cognitive or behavioral consequences can be especially relevant.

Projects submitted under this mechanism are expected to address at least one of two stated overarching challenges. The first is “Quality of Life,” which focuses on developing or evaluating technologies, tests, interventions, epidemiological studies, or devices that could directly benefit individuals living with shared or similar symptom profiles across TBI and AD. The second is “Caregiver Burden,” which targets approaches that measurably reduce strain on caregivers supporting people affected by these common symptoms. Applicants can focus on one challenge or explicitly integrate both, as long as the proposal clearly connects the work to improvements in everyday functioning, well-being, or caregiving demands rather than purely mechanistic or discovery science.

In addition to aligning with one or both overarching challenges, applications must also address at least one FY14 PRARP focus area, or justify clearly why another area is appropriate. One major focus area is “Care Interventions and Quality of Life,” covering research intended to stabilize or improve quality of life for individuals affected by shared TBI and AD symptoms. Examples named in the announcement include cognitive training interventions, health and wellness studies, behavioral interventions, and neuropsychological interventions. The other key focus area is “Caregiver Support,” which emphasizes programs or tools designed to reduce the intensity or difficulty of caregiving. Examples include caregiver training, home-based support, behavioral interventions, and relationship interventions, reflecting an interest in practical supports that can be delivered in real-world settings and improve outcomes for both the caregiver and the care recipient.

Although clinical research can be supported through the QUAL mechanism, the program explicitly discourages drug-centered work. Specifically discouraged areas include pharmacologic interventions that require investigational or FDA-approved drugs or medicines, and drug discovery and development efforts aimed at producing investigational agents. In other words, the program is oriented toward non-pharmacological solutions such as behavioral, psychosocial, cognitive, supportive, technological, or care-delivery innovations that can reduce symptom burden and improve daily living and caregiving experiences.

From an administrative standpoint, the opportunity was released as Funding Opportunity Number W81XWH-14-PRARP-QUAL under CFDA 12.420 (Military Medical Research and Development). It offered approximately $2.6 million in total estimated funding with an expectation of making about four awards. The funding instruments listed were grants and cooperative agreements, and eligibility was described as unrestricted (open to any type of entity), with the caveat that applicants should follow any clarifications in the full announcement. There was no cost sharing or matching requirement. The posting date was September 11, 2014, with a closing date in mid-January 2015 and an archive date in February 2015. For access issues or administrative questions, the announcement directed applicants to the CDMRP Help Desk at 301-682-5507.

Frequently Asked Questions (FAQs) - DoD Peer Reviewed Alzheimers Quality of Life Research Award (FY14 PRARP QUAL)

What is the FY14 PRARP Quality of Life Research Award (QUAL)?

The FY14 PRARP Quality of Life Research Award (QUAL) is a Department of the Army funding opportunity administered through the Congressionally Directed Medical Research Programs (CDMRP). It supports research intended to ease day-to-day impacts experienced by people affected by overlapping symptoms seen in both traumatic brain injury (TBI) and Alzheimers disease (AD), with an emphasis on practical improvements to everyday functioning and caregiving.

What is the main goal of this award?

The central goal is to reduce the burden on affected individuals and on the people who care for them. The program places particular emphasis on needs within the military community, where TBI exposure and long-term cognitive or behavioral consequences may be especially relevant.

What types of problems or needs is this program trying to address?

The program targets real-world challenges linked to overlapping symptom profiles across TBI and AD, focusing on interventions, supports, or tools that improve daily living, well-being, and caregiving demands rather than purely mechanistic or discovery-oriented science.

What overarching challenges must projects address?

Projects are expected to address at least one of two overarching challenges: (1) Quality of Life, or (2) Caregiver Burden. Applicants may address one challenge or integrate both, as long as the proposal clearly connects to improvements in everyday functioning, well-being, or caregiving demands.

What does the "Quality of Life" challenge include?

The Quality of Life challenge focuses on developing or evaluating technologies, tests, interventions, epidemiological studies, or devices that could directly benefit individuals living with shared or similar symptom profiles across TBI and AD.

What does the "Caregiver Burden" challenge include?

The Caregiver Burden challenge focuses on approaches that measurably reduce strain on caregivers who support people affected by overlapping symptoms common to TBI and AD.

Do proposals have to cover both Quality of Life and Caregiver Burden?

No. Applicants can focus on one challenge or integrate both. The key requirement is that the work is clearly tied to improving daily functioning, well-being, or caregiving demands.

Are there specific focus areas applicants must address?

Yes. In addition to aligning with one or both overarching challenges, applications must address at least one FY14 PRARP focus area, or clearly justify why another area is appropriate.

What are the FY14 PRARP focus areas described in the announcement?

The announcement describes two major focus areas: (1) Care Interventions and Quality of Life, and (2) Caregiver Support.

What falls under the "Care Interventions and Quality of Life" focus area?

This focus area covers research intended to stabilize or improve quality of life for individuals affected by shared TBI and AD symptoms. Examples named include cognitive training interventions, health and wellness studies, behavioral interventions, and neuropsychological interventions.

What falls under the "Caregiver Support" focus area?

This focus area emphasizes programs or tools designed to reduce the intensity or difficulty of caregiving. Examples named include caregiver training, home-based support, behavioral interventions, and relationship interventions, with an emphasis on practical supports that can work in real-world settings.

Is clinical research allowed under this award mechanism?

Yes, clinical research can be supported under the QUAL mechanism, as long as the research aligns with the stated challenges and focus areas and remains oriented toward improving quality of life and/or reducing caregiver burden.

Does this program fund drug discovery or drug-based interventions?

No. The program explicitly discourages drug-centered work, including pharmacologic interventions that require investigational or FDA-approved drugs or medicines, and drug discovery and development efforts aimed at producing investigational agents.

If drug-centered work is discouraged, what kinds of solutions are encouraged?

The opportunity is oriented toward non-pharmacological solutions such as behavioral, psychosocial, cognitive, supportive, technological, or care-delivery innovations that reduce symptom burden and improve daily living and caregiving experiences.

What is the Funding Opportunity Number for this award?

The Funding Opportunity Number is W81XWH-14-PRARP-QUAL.

What CFDA program is associated with this opportunity?

The opportunity is associated with CFDA 12.420, Military Medical Research and Development.

How much total funding was estimated for this opportunity?

The total estimated funding was approximately $2.6 million.

How many awards were expected to be made?

The announcement indicated an expectation of making about four awards.

What funding instruments were used for this opportunity?

The listed funding instruments were grants and cooperative agreements.

Who was eligible to apply?

Eligibility was described as unrestricted (open to any type of entity), with the note that applicants should follow any clarifications in the full announcement.

Was cost sharing or matching required?

No. The announcement stated there was no cost sharing or matching requirement.

When was the opportunity posted?

The posting date was September 11, 2014.

What were the application deadline and archive dates?

The closing date was in mid-January 2015, and the archive date was in February 2015.

Who should applicants contact for access issues or administrative questions?

The announcement directed applicants to the CDMRP Help Desk at 301-682-5507 for access issues or administrative questions.

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