Opportunity Information: Apply for W81XWH 10 PRCRP IDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Peer Reviewed Cancer Idea Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jun 7, 2010 and posted on May 20, 2010.
  • Applicants must submit their applications by Oct 20, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $8,440,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 12 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 10 PRCRP IDA

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Opportunity Summary:

The DOD Peer Reviewed Cancer Research Program (PRCRP) Idea Award (Funding Opportunity Number W81XWH-10-PRCRP-IDA) is a Department of the Army/USAMRAA grant and cooperative agreement opportunity designed to back early-stage, conceptually original cancer research ideas that are not yet fully developed but could produce outsized impact. The program explicitly targets high risk/high reward projects that might open new lines of investigation or lead to major advances, especially in areas aligned with the FY10 PRCRP Topic Areas. A key feature of this mechanism is that preliminary data are not required, which lowers the barrier for novel concepts that have a strong scientific rationale but have not yet generated extensive supporting datasets. Even so, proposals are expected to be rigorous: the work needs a well-formulated, testable hypothesis and a clear rationale explaining why the idea is scientifically sound and why it could change the field if successful.

The announcement makes a clear distinction around human subjects research. Studies that involve human participants can be supported, but clinical trials are not allowed under this mechanism. The opportunity uses a standard definition of a clinical trial as a prospective study in which an intervention (such as a drug, device, behavioral approach, or surgical procedure) is tested in human subjects to measure outcomes. What is allowed instead are correlative human subject studies, sometimes called correlative clinical research. These can include prospective or retrospective collection and analysis of human samples or data (for example tissue, blood, bone marrow, nail clippings, or behavioral documentation) to answer research questions about cancer and/or interventions, as long as the study is not designed to test the effectiveness of an intervention for prevention, diagnosis, treatment, or quality-of-life outcomes. Correlative studies may still require informed consent and may involve identifiable information, and applicants are directed to follow the program's general application instructions for compliance requirements related to human subjects, data, and anatomical substances.

From a funding and administrative standpoint, the opportunity is categorized as discretionary and supports science and technology research and development. It lists an expected 12 awards with an estimated total funding level of $8,440,000 and notes there is no cost sharing or matching requirement. Eligibility is described as unrestricted, meaning it is broadly open to many entity types unless additional eligibility details in the full announcement add constraints. The CFDA number associated with the program is 12.420 (Military Medical Research and Development). The opportunity was posted May 20, 2010, with an original and current closing date of October 20, 2010, and an archive date of November 19, 2010, indicating this specific solicitation cycle is historical but still useful as a reference for how the Idea Award mechanism is structured.

The description also provides context on competitiveness and track record: the mechanism was introduced in FY09, and up to the time of the FY10 announcement, 38 applications had been received with 6 recommended for funding. That history signals that the program is selective and is looking for ideas that are both bold and credible, with a clear pathway to high impact despite the inherent risk. For support, the announcement points applicants to the CDMRP/PA and eReceipt help contacts, which are typically used for troubleshooting access to the full announcement and resolving submission issues.

FAQs: DOD PRCRP Idea Award (W81XWH-10-PRCRP-IDA)

What is the DOD PRCRP Idea Award?

The Peer Reviewed Cancer Research Program (PRCRP) Idea Award is a Department of the Army/USAMRAA funding opportunity intended to support early-stage, conceptually original cancer research ideas that are not yet fully developed, but that could lead to major advances or open new lines of investigation.

What kind of research is this award designed to support?

This mechanism explicitly targets high risk/high reward projects. It is meant for bold ideas that could produce outsized impact if successful, especially ideas aligned with the FY10 PRCRP Topic Areas.

Are preliminary data required to apply?

No. A key feature of the Idea Award mechanism is that preliminary data are not required, which helps lower barriers for novel concepts that have not yet generated extensive supporting datasets.

If preliminary data are not required, what does the program expect from the science?

Even without preliminary data, applications are expected to be rigorous. The work should include a well-formulated, testable hypothesis and a clear scientific rationale explaining why the idea is sound and why it could change the field if successful.

Does this opportunity support research involving human subjects?

Yes. Studies involving human participants can be supported under this mechanism, subject to compliance expectations described in the program's general application instructions.

Are clinical trials allowed under the PRCRP Idea Award?

No. Clinical trials are not allowed under this mechanism.

How does the announcement define a clinical trial?

The opportunity uses a standard definition: a clinical trial is a prospective study in human subjects where an intervention (such as a drug, device, behavioral approach, or surgical procedure) is tested to measure outcomes.

What types of human-subjects studies are allowed if clinical trials are not permitted?

The mechanism allows correlative human subject studies (also described as correlative clinical research). These can involve prospective or retrospective collection and analysis of human samples or data to answer research questions about cancer and/or interventions, as long as the study is not designed to test the effectiveness of an intervention for prevention, diagnosis, treatment, or quality-of-life outcomes.

What are examples of allowable correlative samples or data?

Examples listed include tissue, blood, bone marrow, nail clippings, and behavioral documentation, as well as other human-derived samples or data used for analysis within a correlative research design.

Can an allowable correlative study still require informed consent or include identifiable information?

Yes. Correlative studies may still require informed consent and may involve identifiable information. Applicants are directed to follow the program's general application instructions for compliance requirements related to human subjects, data, and anatomical substances.

What federal program identifier is associated with this opportunity?

The CFDA number listed is 12.420, Military Medical Research and Development.

What type of funding opportunity is this (grant vs. other types)?

The announcement describes this as a Department of the Army/USAMRAA grant and cooperative agreement opportunity.

Is this opportunity considered discretionary funding?

Yes. The opportunity is categorized as discretionary.

What general activity category does it fall under?

It supports science and technology research and development.

How many awards were expected and what was the estimated total funding?

The announcement lists an expected 12 awards with an estimated total funding level of $8,440,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is broadly open to many entity types, unless additional details in the full announcement add constraints.

When was this funding opportunity posted and when did it close?

It was posted on May 20, 2010. The original and current closing date listed is October 20, 2010.

Is this solicitation still active?

This specific solicitation cycle is historical. It shows an archive date of November 19, 2010, indicating it is no longer open, though it can still be useful as a reference for how the Idea Award mechanism is structured.

How competitive is the Idea Award mechanism based on the information provided?

The description notes the mechanism was introduced in FY09 and that, up to the time of the FY10 announcement, 38 applications had been received with 6 recommended for funding. This suggests the program is selective and emphasizes ideas that are both bold and credible.

Where can applicants get help with the announcement or submission issues?

The opportunity points applicants to CDMRP/PA and eReceipt help contacts, which are typically used for troubleshooting access to the full announcement and resolving submission issues.

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Previous opportunity: ANNOUNCEMENT OF OPPORTUNITY FOR THE DISCOVERY PROGRAM DISCOVERY 2010

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