Opportunity Information: Apply for W81XWH 14 PRMRP CTA
Apply for W81XWH 14 PRMRP CTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 30, 2014 and posted on Apr 30, 2014.
- Applicants must submit their applications by Oct 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $36,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award (Funding Opportunity Number W81XWH-14-PRMRP-CTA) is a Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA) funding opportunity intended to move clinical trials forward quickly when they have strong potential to meaningfully affect prevention, diagnosis, treatment, or clinical management of diseases and conditions that fall within at least one of the Congressionally directed FY14 PRMRP Topic Areas. In practical terms, the program is looking for well-justified trials that can generate actionable evidence, not just preliminary lab findings, and that align clearly with the specific topic areas laid out in the associated program announcement.
The award supports a wide range of clinical trial designs and maturity levels, from smaller early-stage efforts meant to test feasibility or inform next-step trial design (such as pilot studies, first-in-human work, or Phase 0-type trials) through to larger, more definitive trials intended to determine efficacy in relevant patient populations. The types of interventions and approaches that can be evaluated are broad, including new or repurposed pharmacologic agents (drugs or biologics), medical devices, clinical guidance or care pathways, and emerging technologies or other innovative clinical approaches. The emphasis is on trials that are ready to be implemented rapidly and that have a plausible path to significant impact in the targeted medical area.
A core requirement is relevance to military health needs. Proposed studies must be responsive to the health care needs of military Service members, Veterans, and/or other military beneficiaries. At the same time, the program does not require that the study population be drawn from military or Veteran groups, meaning applicants can propose trials in civilian settings as long as they make a credible case that the findings will translate to and benefit the military and Veteran health context.
Administratively, this opportunity was posted on April 30, 2014, with an original and final closing date of October 17, 2014, and it was archived on November 16, 2014. The funding instrument types listed include both cooperative agreements and grants, under the broader activity category of science and technology and other research and development. The estimated total funding amount was $36,000,000, with an expectation of making about 6 awards, and there was no cost sharing or matching requirement. Eligibility was described as unrestricted, meaning it was open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement text.
The opportunity is associated with CFDA number 12.420 (Military Medical Research and Development). For support accessing the full announcement, the listed contact was the CDMRP Help Desk (phone 301-682-5507; email help@eBRAP.org).
PRMRP Clinical Trial Award (W81XWH-14-PRMRP-CTA) FAQs
What is the PRMRP Clinical Trial Award?
The Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award is a U.S. Department of Defense funding opportunity managed by the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is intended to move clinical trials forward quickly when they have strong potential to meaningfully affect prevention, diagnosis, treatment, or clinical management of diseases and conditions that fall within at least one of the Congressionally directed FY14 PRMRP Topic Areas.
What is the funding opportunity number for this award?
The Funding Opportunity Number is W81XWH-14-PRMRP-CTA.
What is the main purpose or priority of this award?
The priority is to support well-justified clinical trials that can generate actionable evidence and that align clearly with the FY14 PRMRP Topic Areas described in the associated program announcement. The program emphasizes trials that are ready to be implemented rapidly and have a plausible path to significant impact in the targeted medical area.
What kinds of research does this award support?
This award supports clinical trials across a range of designs and maturity levels, from smaller early-stage efforts (such as feasibility or pilot studies, first-in-human work, or Phase 0-type trials) to larger, more definitive trials intended to determine efficacy in relevant patient populations.
Are early-stage or pilot clinical trials allowed?
Yes. The opportunity explicitly includes smaller early-stage efforts meant to test feasibility or inform next-step trial design, including pilot studies, first-in-human work, and Phase 0-type trials.
Are larger, efficacy-focused trials allowed?
Yes. The award also supports larger, more definitive trials intended to determine efficacy in relevant patient populations.
What types of interventions or approaches can be studied in supported trials?
The opportunity allows a broad range of interventions and approaches, including new or repurposed pharmacologic agents (drugs or biologics), medical devices, clinical guidance or care pathways, emerging technologies, and other innovative clinical approaches.
Do proposed projects have to fit specific medical areas?
Yes. Proposed trials must address diseases and conditions that fall within at least one of the Congressionally directed FY14 PRMRP Topic Areas, as laid out in the associated program announcement.
Is military relevance required?
Yes. A core requirement is relevance to military health needs. Proposed studies must be responsive to the health care needs of military Service members, Veterans, and/or other military beneficiaries.
Does the study population have to be military Service members or Veterans?
No. The opportunity states that the study population is not required to be drawn from military or Veteran groups. Trials can be conducted in civilian settings as long as applicants provide a credible case that the findings will translate to and benefit the military and Veteran health context.
What funding mechanisms are used for this opportunity?
The listed funding instrument types include cooperative agreements and grants.
What is the activity category for this funding opportunity?
The activity category is science and technology and other research and development.
How much total funding was estimated for this opportunity?
The estimated total funding amount was $36,000,000.
How many awards were expected to be made?
The opportunity anticipated making about 6 awards.
Is cost sharing or matching required?
No. The opportunity indicates there was no cost sharing or matching requirement.
Who was eligible to apply?
Eligibility was described as unrestricted, meaning it was open to any type of applicant entity, subject to any additional eligibility clarifications in the full announcement text.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 12.420 (Military Medical Research and Development).
When was this opportunity posted?
It was posted on April 30, 2014.
What were the closing dates for applications?
The original and final closing date listed was October 17, 2014.
When was the opportunity archived?
It was archived on November 16, 2014.
Where can applicants get help accessing the full announcement?
Support for accessing the full announcement was available through the CDMRP Help Desk at 301-682-5507 or help@eBRAP.org.
Which DoD organization was associated with this funding opportunity?
The opportunity was issued under the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).
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