Opportunity Information: Apply for W81XWH 14 PRMRP IIRA
Apply for W81XWH 14 PRMRP IIRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical Investigator Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 30, 2014 and posted on Apr 30, 2014.
- Applicants must submit their applications by Oct 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $76,500,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 40 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Medical Investigator Initiated Research Award (PRMRP IIRA) is a Department of Defense medical research funding opportunity designed to support investigator-driven studies that can meaningfully advance research and/or improve patient care for diseases or conditions that fall within at least one of the Congressionally directed FY14 Peer Reviewed Medical Research Program (PRMRP) Topic Areas. In practical terms, this award is meant for projects where the core idea originates from the investigator rather than being narrowly prescribed by the funder, as long as the work clearly aligns with one or more of the specific topic areas identified in the official program announcement.
A central expectation of this opportunity is that proposed research should be grounded in a well-supported scientific or clinical rationale. The solicitation explicitly recognizes that strong, impactful research questions can come from many legitimate sources, including laboratory discoveries, population-based or epidemiologic observations, a clinician’s direct experience with patient needs, or even carefully considered anecdotal or real-world clinical observations. However, the application is not meant to be purely speculative. Applicants are required to include relevant supporting data that justify the research direction and demonstrate feasibility or a compelling basis for the study. Those supporting data can be unpublished (for example, preliminary results from the applicant’s lab or clinic) or drawn from the published scientific literature, as long as they credibly support the proposed approach.
From a funding and administrative standpoint, this opportunity was offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under Funding Opportunity Number W81XWH-14-PRMRP-IIRA. Awards could be made as either grants or cooperative agreements, indicating that projects might be supported through standard assistance mechanisms and, depending on the specific award, may involve varying degrees of programmatic involvement consistent with federal cooperative agreement practices. The activity category is science and technology and other research and development, reflecting its focus on biomedical and translational research that can have downstream patient-care relevance.
The program anticipated making about 40 awards, supported by an estimated total funding pool of $76.5 million. There was no cost sharing or matching requirement, which generally lowers barriers for applicants who may not have institutional or external funds available to contribute. Eligibility was listed as unrestricted, meaning it was broadly open to many types of applicant organizations, subject to any additional eligibility clarifications contained in the full announcement text. The assistance listing tied to the opportunity is CFDA 12.420 (Military Medical Research and Development), which is commonly associated with DoD-sponsored biomedical research funding.
Key timing details in the posted notice include an original and final application closing date of October 17, 2014, with the opportunity posted on April 30, 2014 and archived on November 16, 2014. For applicant support, the notice directs users who have trouble accessing the full announcement to contact the CDMRP Help Desk at 301-682-5507 or by email at help@eBRAP.org, which reflects the common CDMRP workflow where applicants use eBRAP for parts of the pre-application and submission process, depending on the year and the specific mechanism.
Overall, the PRMRP Investigator Initiated Research Award can be summarized as a relatively flexible, investigator-led DoD biomedical research mechanism aimed at producing a meaningful contribution to knowledge and/or clinical care in one of the specified FY14 PRMRP topic areas, with an emphasis on proposals that are strongly justified by existing evidence and supported by relevant preliminary or literature-based data.
DoD Peer Reviewed Medical Investigator Initiated Research Award (PRMRP IIRA) FAQs
What is the PRMRP Investigator Initiated Research Award (IIRA)?
The PRMRP IIRA is a Department of Defense (DoD) medical research funding opportunity intended to support investigator-driven studies that meaningfully advance research and/or improve patient care for diseases or conditions that fall within at least one of the Congressionally directed FY14 Peer Reviewed Medical Research Program (PRMRP) Topic Areas.
Who is offering this funding opportunity?
This opportunity was offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number listed for this program is W81XWH-14-PRMRP-IIRA.
What types of projects does this award support?
This award supports investigator-initiated (investigator-driven) biomedical research projects where the core idea originates from the investigator, as long as the proposed work clearly aligns with one or more of the specific FY14 PRMRP Topic Areas identified in the official program announcement.
What does "investigator-initiated" mean in the context of this award?
"Investigator-initiated" means the project concept and primary research question are generated by the applicant rather than being narrowly defined by the funder, while still requiring clear alignment with one or more FY14 PRMRP Topic Areas.
Do projects need to align to specific topic areas?
Yes. Proposed research must address a disease or condition that falls within at least one of the Congressionally directed FY14 PRMRP Topic Areas.
What is a central expectation for the proposed research?
A central expectation is that the research is grounded in a well-supported scientific or clinical rationale and is not purely speculative.
What kinds of rationales or idea sources are considered legitimate for this solicitation?
The solicitation recognizes that strong research questions may originate from multiple legitimate sources, including laboratory discoveries, population-based or epidemiologic observations, a clinician's direct experience with patient needs, or carefully considered anecdotal or real-world clinical observations.
Is supporting data required?
Yes. Applicants are required to include relevant supporting data that justify the research direction and demonstrate feasibility or provide a compelling basis for the study.
What types of supporting data are acceptable?
Supporting data may be unpublished (such as preliminary results from the applicant's laboratory or clinic) or drawn from the published scientific literature, as long as the information credibly supports the proposed approach.
Does the program allow applications based only on speculative ideas?
No. The program description indicates the application is not intended to be purely speculative; it must be supported by relevant evidence and rationale.
What funding mechanisms may be used for awards under this opportunity?
Awards could be made as either grants or cooperative agreements, meaning projects may be supported through standard assistance mechanisms and, depending on the specific award, may involve varying degrees of programmatic involvement consistent with federal cooperative agreement practices.
What is the activity category for this opportunity?
The activity category is science and technology and other research and development, reflecting a focus on biomedical and translational research with patient-care relevance.
How many awards were anticipated?
The program anticipated making about 40 awards.
What was the estimated total funding available?
The estimated total funding pool was $76.5 million.
Is cost sharing or matching required?
No. There was no cost sharing or matching requirement listed for this opportunity.
Who is eligible to apply?
Eligibility was listed as unrestricted, meaning it was broadly open to many types of applicant organizations, subject to any additional eligibility clarifications contained in the full announcement text.
What is the CFDA/Assistance Listing number associated with this opportunity?
The assistance listing tied to the opportunity is CFDA 12.420 (Military Medical Research and Development).
When was the opportunity posted?
The notice indicates the opportunity was posted on April 30, 2014.
What was the application closing date?
The original and final application closing date listed in the notice was October 17, 2014.
When was the opportunity archived?
The notice indicates the opportunity was archived on November 16, 2014.
What should applicants do if they cannot access the full announcement?
The notice directs users who have trouble accessing the full announcement to contact the CDMRP Help Desk at 301-682-5507 or by email at help@eBRAP.org.
How does eBRAP relate to this opportunity?
The notice references the CDMRP Help Desk and the email address help@eBRAP.org, reflecting the common CDMRP workflow where applicants use eBRAP for parts of the pre-application and submission process, depending on the year and the specific mechanism.
What is the overall goal of the PRMRP IIRA?
The overall goal is to fund relatively flexible, investigator-led DoD biomedical research that produces a meaningful contribution to knowledge and/or clinical care in one of the specified FY14 PRMRP Topic Areas, with proposals strongly justified by existing evidence and supported by relevant data.
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