Opportunity Information: Apply for W81XWH 11 PRORP CTA
Apply for W81XWH 11 PRORP CTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Orthopaedic Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jul 9, 2011 and posted on Jul 9, 2011.
- Applicants must submit their applications by Dec 5, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $13,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Orthopaedic Clinical Trial Award (PRORP CTA), Funding Opportunity Number W81XWH-11-PRORP-CTA, is a U.S. Department of the Army (USAMRAA) funding opportunity under CFDA 12.420 (Military Medical Research and Development) aimed at quickly launching clinical trials that could meaningfully improve care for combat-relevant orthopaedic injuries. The focus is on practical, near-term clinical testing rather than early exploratory work, with the core intent being rapid implementation of trials that can lead to real changes in treatment, rehabilitation, and outcomes for service members and Veterans affected by orthopaedic trauma linked to military service and combat conditions.
This award supports clinical trials that evaluate interventions with clear potential to affect orthopaedic injury care in military contexts. Trial concepts can include promising new products, pharmacologic agents (including drugs and biologics), medical devices, clinical guidance or protocols, and emerging approaches or technologies. In other words, applicants are expected to bring forward interventions that are ready for rigorous clinical evaluation, with a rationale that they could address problems commonly seen in combat-related orthopaedic injury, such as complex extremity trauma, bone and joint damage, and related functional impairments.
A central requirement is demonstrating strong military relevance. Every application must clearly justify how the proposed trial addresses the needs of military and/or Veteran populations impacted by combat-relevant orthopaedic injuries. The program explicitly encourages collaboration with military researchers and clinicians, reflecting a preference for proposals that are grounded in military medical realities and can be integrated into military or VA-related care settings. Proposals that include active duty service members or Veterans as all or part of the study population are given higher priority for funding, signaling that direct applicability to these groups is a key review and selection factor.
From an administrative and funding standpoint, the opportunity is categorized as discretionary research and development funding in the science and technology area, with awards made as grants and/or cooperative agreements. The expected number of awards is six, supported by an estimated total funding level of $13,000,000. There is no cost-sharing or matching requirement, and eligibility is listed as unrestricted, meaning a wide range of entity types may apply (subject to any additional eligibility clarifications contained in the full announcement).
Key dates provided in the source data show the opportunity was posted July 9, 2011, with an original and current closing date of December 5, 2011, and an archive date of January 4, 2012. For assistance accessing the full announcement, the listing provides the CDMRP Help Desk contact information at 301-682-5507 and help@cdmrp.org.
FAQs: DoD Peer Reviewed Orthopaedic Clinical Trial Award (PRORP CTA) - W81XWH-11-PRORP-CTA
What is this funding opportunity?
The DoD Peer Reviewed Orthopaedic Clinical Trial Award (PRORP CTA) is a U.S. Department of the Army (USAMRAA) funding opportunity intended to rapidly launch clinical trials that can meaningfully improve care for combat-relevant orthopaedic injuries. The emphasis is on near-term, practical clinical testing designed to lead to real changes in treatment, rehabilitation, and outcomes for Service Members and Veterans affected by orthopaedic trauma linked to military service and combat conditions.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is W81XWH-11-PRORP-CTA.
Which agency is offering the award?
The opportunity is offered by the U.S. Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity).
What CFDA program does this fall under?
This opportunity is listed under CFDA 12.420, Military Medical Research and Development.
What is the overall goal of the PRORP CTA?
The goal is to quickly initiate clinical trials that have a clear pathway to improving clinical care for combat-relevant orthopaedic injuries. The core intent is rapid implementation of trials that can translate into tangible improvements in patient care and functional outcomes in military and Veteran populations.
Is this opportunity focused on basic research or clinical trials?
This opportunity is focused on clinical trials and near-term clinical testing rather than early exploratory or basic research. Applicants are expected to propose interventions that are ready for rigorous clinical evaluation.
What kinds of studies are supported?
The award supports clinical trials evaluating interventions with clear potential to affect orthopaedic injury care in military contexts, especially where results could influence treatment, rehabilitation, and outcomes.
What types of interventions can be tested in proposed clinical trials?
Trial concepts may include:
- Promising new products
- Pharmacologic agents, including drugs and biologics
- Medical devices
- Clinical guidance or protocols
- Emerging approaches or technologies
The opportunity description indicates that the intervention should be sufficiently mature for clinical testing and supported by a rationale for its relevance to combat-related orthopaedic injury care.
What injury areas or clinical needs are emphasized as combat-relevant?
The opportunity references combat-related orthopaedic injuries and trauma linked to military service and combat conditions, including examples such as complex extremity trauma, bone and joint damage, and related functional impairments.
How important is military relevance?
Military relevance is a central requirement. Each application must clearly justify how the proposed trial addresses the needs of military and/or Veteran populations impacted by combat-relevant orthopaedic injuries.
Are collaborations with military researchers or clinicians encouraged?
Yes. The program explicitly encourages collaboration with military researchers and clinicians, reflecting a preference for proposals grounded in military medical realities and capable of integration into military or VA-related care settings.
Are studies involving active duty Service Members or Veterans prioritized?
Yes. Proposals that include active duty Service Members or Veterans as all or part of the study population are given higher priority for funding, indicating that direct applicability to these groups is an important factor in review and selection.
What type of funding mechanism is used?
Awards are made as grants and/or cooperative agreements.
How is the opportunity categorized?
It is categorized as discretionary research and development funding in the science and technology area.
How many awards are expected?
The expected number of awards is six.
What is the estimated total funding available?
The estimated total funding level is $13,000,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is listed as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications contained in the full announcement.
When was the opportunity posted?
The opportunity was posted on July 9, 2011.
What is the application closing date?
The original and current closing date listed is December 5, 2011.
When was the opportunity archived?
The archive date is January 4, 2012.
Where can applicants get help accessing the full announcement?
For assistance accessing the full announcement, the listing provides the CDMRP Help Desk at 301-682-5507 or help@cdmrp.org.
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