Opportunity Information: Apply for W81XWH 11 PRORP TRPA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Orthopaedic Translational Research Partnership Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jul 9, 2011 and posted on Jul 9, 2011.
  • Applicants must submit their applications by Dec 5, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,500,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 11 PRORP TRPA

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Opportunity Summary:

The DoD Peer Reviewed Orthopaedic Translational Research Partnership Award (TRPA) is a U.S. Department of the Army (USAMRAA) funding opportunity under the Congressionally Directed Medical Research Programs focus on orthopaedic research, aimed specifically at speeding up translational work that can move strong laboratory or early-stage concepts into real-world clinical use. The core purpose is to improve care and outcomes for Warfighters who suffer combat-relevant traumatic orthopaedic injuries, meaning the program is looking for projects that do more than basic discovery and instead actively push toward practical clinical application.

A defining feature of this award is its emphasis on true collaboration through a formal research partnership. Rather than supporting a single investigator working independently, the TRPA is structured to require a multi-institutional, multidisciplinary team made up of two or three investigators who serve as designated “partners.” The intent is that the partnership itself should be essential to the work, enabling progress that would be difficult to achieve if each investigator pursued separate, uncoordinated projects. In practical terms, the program is signaling that it wants integrated teams that can combine complementary expertise, share resources, and align the research plan around a coherent translational pathway.

The required makeup of the partnership is also very explicit: the team must include at least one laboratory scientist and at least one clinician. This requirement reflects the translational goal of the award, ensuring that promising scientific approaches are informed by clinical realities and that the project is positioned to move toward patient-oriented testing, adoption, or implementation. The presence of both perspectives is meant to reduce the common gap where laboratory advances fail to match clinical needs or where clinical ideas lack the mechanistic and development support needed to mature into usable interventions.

Administratively, this opportunity was offered as a discretionary federal funding program using either a cooperative agreement or a grant mechanism, within the “Science and Technology and other Research and Development” category. The assistance listing associated with the program is CFDA 12.420 (Military Medical Research and Development). The announcement anticipated making about four awards, with an estimated total funding level of $4.5 million across the competition. There was no cost-sharing or matching requirement, which generally lowers barriers for applicants by not requiring the institution or investigators to commit additional non-federal funds as a condition of receiving the award.

Eligibility was described as unrestricted, meaning it was broadly open to many entity types, subject to any additional clarifications in the full announcement’s eligibility section. The opportunity was posted on July 9, 2011, with an original and final closing date of December 5, 2011, and it was archived on January 4, 2012. For applicants who needed help accessing the complete announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507 and help@cdmrp.org.

Peer Reviewed Orthopaedic Translational Research Partnership Award (TRPA) - FAQs

What is the DoD Peer Reviewed Orthopaedic Translational Research Partnership Award (TRPA)?

The TRPA is a U.S. Department of the Army (USAMRAA) funding opportunity under the Congressionally Directed Medical Research Programs (CDMRP) focused on orthopaedic research. It is designed to speed up translational work that moves strong laboratory or early-stage concepts toward real-world clinical use.

What is the main purpose of this award?

The core purpose is to improve care and outcomes for Warfighters who suffer combat-relevant traumatic orthopaedic injuries. The program emphasizes projects that go beyond basic discovery and actively push toward practical clinical application.

What kind of research does the TRPA prioritize?

The TRPA prioritizes translational orthopaedic research, meaning work that is aimed at moving promising laboratory findings or early concepts along a pathway toward clinical use, adoption, or implementation.

Does this award support basic research only?

No. The opportunity is explicitly aimed at speeding up translational work rather than supporting basic discovery alone. Projects are expected to push toward practical clinical application.

Is a formal collaboration required to apply?

Yes. A defining feature of the TRPA is its emphasis on true collaboration through a formal research partnership. The award is structured to require a multi-institutional, multidisciplinary team made up of two or three investigators who serve as designated partners.

How many investigators can be part of the required partnership?

The required partnership is made up of two or three investigators serving as designated partners.

Does the partnership need to be multi-institutional and multidisciplinary?

Yes. The TRPA calls for a multi-institutional, multidisciplinary team. The intent is to bring together complementary expertise and resources to support a coherent translational pathway.

What roles must be represented on the partnership team?

The team must include at least one laboratory scientist and at least one clinician. This is intended to ensure that the work is informed by clinical realities while also being supported by the scientific and development expertise needed to move toward clinical use.

Why does the TRPA require both a laboratory scientist and a clinician?

The requirement reflects the translational goal of the award. It is meant to reduce the common gap where laboratory advances fail to match clinical needs or where clinical ideas lack the mechanistic and development support needed to mature into usable interventions.

What does the program mean by an "essential" partnership?

The partnership itself should be essential to the work, enabling progress that would be difficult to achieve if each investigator pursued separate, uncoordinated projects. The expectation is that the team integrates expertise, shares resources, and aligns around a single, coherent translational plan.

Which agency and program are associated with this opportunity?

This is a U.S. Department of the Army (USAMRAA) opportunity offered under the Congressionally Directed Medical Research Programs (CDMRP).

What funding mechanism was used for this opportunity?

The opportunity was offered as a discretionary federal funding program using either a cooperative agreement or a grant mechanism.

What category does this funding opportunity fall under?

It falls within the "Science and Technology and other Research and Development" category.

What is the assistance listing (CFDA) number for this program?

The assistance listing associated with the program is CFDA 12.420 (Military Medical Research and Development).

How many awards were expected to be made?

The announcement anticipated making about four awards.

What was the estimated total funding level for the competition?

The estimated total funding level was $4.5 million across the competition.

Was cost-sharing or matching required?

No. There was no cost-sharing or matching requirement.

What does "eligibility was described as unrestricted" mean in this announcement?

Eligibility was described as unrestricted, meaning it was broadly open to many entity types, subject to any additional clarifications provided in the full announcement's eligibility section.

When was this opportunity posted?

The opportunity was posted on July 9, 2011.

What was the application deadline?

The original and final closing date listed for the opportunity was December 5, 2011.

When was the opportunity archived?

The opportunity was archived on January 4, 2012.

Who can applicants contact for help accessing the complete announcement?

Applicants needing help accessing the complete announcement were directed to the CDMRP Help Desk at 301-682-5507 or by email at help@cdmrp.org.

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