Opportunity Information: Apply for W81XWH 13 PRORP CTDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Orthopaedic Clinical Trial Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Feb 21, 2013 and posted on Feb 21, 2013.
  • Applicants must submit their applications by Jul 18, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,200,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 13 PRORP CTDA

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Opportunity Summary:

The DoD Peer Reviewed Orthopaedic Clinical Trial Development Award (CTDA) is a U.S. Department of Defense funding opportunity designed to help research teams do the upfront work needed to get a high-impact orthopaedic clinical trial ready to launch, specifically for injuries linked to military combat. Instead of primarily paying for a full clinical trial itself, this award focuses on the planning and development steps that make a trial feasible and competitive, with the goal of moving promising orthopaedic treatments closer to real-world testing in the populations most affected by combat-related injuries.

The program sits under the Peer Reviewed Orthopaedic Research Program (PRORP) and emphasizes clinical trial preparation for therapies that could meaningfully improve outcomes after combat-related orthopaedic trauma. Proposed trials can address any part of treating these injuries as long as they align with the FY13 PRORP CTDA Focus Areas referenced in the announcement. Examples of what the DoD is willing to see include evaluation of new or emerging products, pharmacologic agents (including drugs or biologics), medical devices, clinical practice guidance, and other emerging approaches or technologies that could translate into better care for service members and Veterans dealing with complex musculoskeletal injuries.

A central requirement is military relevance. Every application must clearly justify how the proposed effort matters to military and/or Veteran populations affected by combat-related orthopaedic injury. The announcement also makes it clear that collaboration with military researchers and clinicians is encouraged, which signals that the program values practical alignment with military medicine and the realities of caring for these injuries in DoD or Veteran-related settings. In addition, applications that plan to include active duty service members or Veterans as participants, whether as the full study population or a subset, are positioned to receive higher priority during the programmatic review stage, meaning this factor can influence funding decisions beyond scientific merit alone.

Administratively, this opportunity was issued by the Department of the Army through USAMRAA, under Funding Opportunity Number W81XWH-13-PRORP-CTDA. Awards are made as grants and/or cooperative agreements (the listing includes both, indicating that some projects may involve a closer level of government involvement typical of cooperative agreements). It falls under CFDA 12.420 (Military Medical Research and Development). The program anticipated making about four awards, with an estimated total funding amount of $1,200,000 across the competition. There is no cost-sharing or matching requirement, and eligibility is listed as unrestricted, meaning applicants from a broad range of organization types may apply (subject to any additional eligibility notes that may have been included in the full announcement).

Key dates show this as a FY13-era opportunity: it was posted and created on February 21, 2013, with an original and current closing date of July 18, 2013, and an archive date of August 17, 2013. For support accessing the full announcement, the notice directs applicants to the CDMRP Help Desk at 301-682-5507 or help@cdmrp.org.

Frequently Asked Questions (FAQs) - DoD Peer Reviewed Orthopaedic Clinical Trial Development Award (CTDA)

1. What is the DoD Peer Reviewed Orthopaedic Clinical Trial Development Award (CTDA)?

The CTDA is a U.S. Department of Defense funding opportunity that supports the planning and development work needed to get a high-impact orthopaedic clinical trial ready to launch, with a specific emphasis on injuries linked to military combat.

2. What is the main purpose of this award?

The main purpose is to fund upfront clinical trial development activities that make a proposed orthopaedic trial feasible, well-designed, and competitive, so that promising treatments can move closer to real-world testing in the populations most affected by combat-related injuries.

3. Does this award pay for running a full clinical trial?

Not primarily. The CTDA focuses on trial preparation and development steps rather than funding the full execution of a clinical trial.

4. What program is this opportunity part of?

The CTDA sits under the Peer Reviewed Orthopaedic Research Program (PRORP).

5. What health problem area is the CTDA focused on?

It emphasizes therapies and approaches intended to improve outcomes after combat-related orthopaedic trauma and complex musculoskeletal injuries affecting service members and Veterans.

6. What types of clinical trials or interventions are of interest?

Proposed trials can address any part of treating combat-related orthopaedic injuries, as long as they align with the FY13 PRORP CTDA Focus Areas referenced in the announcement. Examples mentioned include new or emerging products, pharmacologic agents (including drugs or biologics), medical devices, clinical practice guidance, and other emerging approaches or technologies intended to translate into better care.

7. What are the FY13 PRORP CTDA Focus Areas?

The opportunity notes that proposed trials must align with the FY13 PRORP CTDA Focus Areas referenced in the announcement. The specific focus areas are not listed in the summary provided and would need to be confirmed in the full funding announcement.

8. What does "military relevance" mean for this opportunity?

Every application must clearly justify how the proposed effort matters to military and/or Veteran populations affected by combat-related orthopaedic injury. Military relevance is described as a central requirement.

9. Is collaboration with military researchers or clinicians required?

Collaboration is encouraged. The notice signals that the program values practical alignment with military medicine and the realities of care in DoD or Veteran-related settings.

10. Does including active duty service members or Veterans as study participants matter?

Yes. Applications that plan to include active duty service members or Veterans as participants (either as the full study population or a subset) are positioned to receive higher priority during the programmatic review stage. This can influence funding decisions beyond scientific merit alone.

11. Who issued this funding opportunity?

The opportunity was issued by the Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity).

12. What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is W81XWH-13-PRORP-CTDA.

13. What type of award mechanism is used?

Awards are made as grants and/or cooperative agreements. The listing includes both, indicating that some projects may involve closer government involvement typical of cooperative agreements.

14. What is the CFDA number for this program?

The CFDA listing is 12.420 (Military Medical Research and Development).

15. How many awards were anticipated?

The program anticipated making about four awards.

16. What was the estimated total funding amount for this competition?

The estimated total funding amount across the competition was $1,200,000.

17. Is cost sharing or matching required?

No. The opportunity states there is no cost-sharing or matching requirement.

18. Who is eligible to apply?

Eligibility is listed as unrestricted, meaning applicants from a broad range of organization types may apply (subject to any additional eligibility notes that may have been included in the full announcement).

19. When was this opportunity posted?

It was posted and created on February 21, 2013.

20. What was the application closing date?

The original and current closing date listed is July 18, 2013.

21. When was the opportunity archived?

The archive date listed is August 17, 2013.

22. Where can applicants get help accessing the full announcement?

The notice directs applicants to the CDMRP Help Desk at 301-682-5507 or by email at help@cdmrp.org.

23. What is the overall goal of the CTDA in terms of real-world impact?

The stated goal is to move promising orthopaedic treatments closer to real-world testing for the populations most affected by combat-related injuries, ultimately aiming to improve outcomes for service members and Veterans.

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