Opportunity Information: Apply for W81XWH 12 PHTBI CAP
Apply for W81XWH 12 PHTBI CAP
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Psychological Health and Traumatic Brain Injury Consortium to Alleviate PTSD Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Sep 6, 2012 and posted on Sep 6, 2012.
- Applicants must submit their applications by Jan 4, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $20,336,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Psychological Health and Traumatic Brain Injury Consortium to Alleviate PTSD Award is a Department of Defense, in collaboration with the Department of Veterans Affairs, funding opportunity designed to build and support a coordinated research consortium focused on improving outcomes for Service Members (Active Duty, National Guard, and Reserve) and Veterans affected by posttraumatic stress disorder. The central aim is to strengthen the full pipeline from understanding PTSD to improving care, emphasizing better diagnostics and prognostics, development of novel treatments, and rehabilitative strategies that can effectively treat acute PTSD and reduce the likelihood that it becomes chronic. The program is framed as a direct response to recommendations highlighted in the DoD/VA sponsored Institute of Medicine report on treatment for PTSD in military and veteran populations, signaling an intent to align funded work with identified gaps in evidence and clinical impact.
A major scientific priority of the consortium is to explain why PTSD does not follow a single course across individuals. The opportunity highlights the need to elucidate factors that shape different PTSD trajectories, including differences in onset, progression, and duration, as well as the downstream mental and physical consequences that often co-occur with PTSD. Examples of these associated sequelae called out in the announcement include depression, anger and aggression, and substance use or abuse, among other long-term complications. In practical terms, the consortium is expected to generate knowledge that clarifies which biological, psychological, social, or exposure-related factors influence whether someone recovers, remains symptomatic, or develops persistent impairment, and how these pathways relate to broader health and functioning over time.
Another core objective is improving the ability to predict who is likely to develop chronic PTSD and who is likely to respond to particular treatments. The announcement emphasizes identification of measures that can help determine risk for chronicity, reflecting an interest in biomarkers, clinical assessment tools, longitudinal indicators, or other predictive approaches that can guide early intervention and personalize care. This predictive focus is paired with an explicit recognition that existing PTSD treatments, while supported extensively by DoD and VA research investments, have not been fully successful for all individuals. A substantial subset of patients does not respond adequately to currently available regimens, and the ability to anticipate treatment response remains a high priority. The consortium model is meant to accelerate progress by coordinating expertise and resources to improve prognostics, advance therapeutic options, and mitigate the negative long-term consequences of traumatic exposure.
From an administrative and funding standpoint, this opportunity was issued as a discretionary cooperative agreement under Funding Opportunity Number W81XWH 12 PHTBI CAP. It falls under the Science and Technology and other Research and Development category and is associated with CFDA 12.420, Military Medical Research and Development. The Department of the Army, through USAMRAA, is the sponsoring agency. The opportunity anticipated a single award, with an estimated total funding level of $20,336,000, and it did not require cost sharing or matching. Eligibility was listed as unrestricted, meaning it was broadly open to different types of applicant organizations, subject to any additional eligibility clarifications contained in the full announcement. The posting date was September 6, 2012, with an original and current closing date of January 4, 2013, and an archive date of February 3, 2013. For access issues related to the full announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
Frequently Asked Questions (FAQs)
What is the DoD Psychological Health and Traumatic Brain Injury Consortium to Alleviate PTSD Award?
It is a Department of Defense (DoD) funding opportunity, developed in collaboration with the Department of Veterans Affairs (VA), to build and support a coordinated research consortium focused on improving outcomes for Service Members and Veterans affected by posttraumatic stress disorder (PTSD).
What is the main purpose of this funding opportunity?
The central aim is to strengthen the full pipeline from understanding PTSD to improving care. The opportunity emphasizes improving diagnostics and prognostics, developing novel treatments, and advancing rehabilitative strategies that can effectively treat acute PTSD and reduce the likelihood that it becomes chronic.
Who is the research intended to help?
The program focuses on outcomes for Service Members (Active Duty, National Guard, and Reserve) and Veterans affected by PTSD.
What does the opportunity mean by a "coordinated research consortium"?
The award is designed to support a consortium model, meaning a coordinated, organized research effort intended to bring together expertise and resources to accelerate progress across multiple parts of the PTSD research and care pipeline (for example, prediction, diagnosis, treatment development, and rehabilitation).
What scientific problem is highlighted as a major priority for the consortium?
A major scientific priority is explaining why PTSD does not follow a single course across individuals. The opportunity highlights the need to understand factors that shape different PTSD trajectories, including differences in onset, progression, and duration.
What are "PTSD trajectories" in the context of this announcement?
In this opportunity, PTSD trajectories refer to how PTSD develops and changes over time across different individuals, including when symptoms begin (onset), how symptoms evolve (progression), and how long symptoms persist (duration).
What kinds of factors is the consortium expected to study to explain different PTSD courses?
The announcement points to biological, psychological, social, and exposure-related factors as examples of influences that may help explain why some individuals recover, some remain symptomatic, and some develop persistent impairment.
Does the opportunity address consequences that can occur alongside PTSD?
Yes. The announcement highlights downstream mental and physical consequences that often co-occur with PTSD. Examples specifically mentioned include depression, anger and aggression, and substance use or abuse, among other long-term complications.
What is meant by improving "diagnostics and prognostics" for PTSD?
Within the framing of this opportunity, diagnostics refers to improving the ability to identify and characterize PTSD, while prognostics refers to improving the ability to predict future outcomes, such as who may develop chronic PTSD or who may respond to specific treatments.
What is the predictive focus of this program?
A core objective is improving the ability to predict who is likely to develop chronic PTSD and who is likely to respond to particular treatments. The announcement emphasizes identifying measures that help determine risk for chronicity and support early intervention and personalized care.
What types of predictive measures are mentioned or implied?
The opportunity expresses interest in measures such as biomarkers, clinical assessment tools, longitudinal indicators, or other predictive approaches that can help determine risk for chronicity and anticipate treatment response.
Why does the announcement emphasize treatment response?
The opportunity notes that existing PTSD treatments, while supported by extensive DoD and VA research investments, have not been fully successful for all individuals. A substantial subset of patients does not respond adequately to currently available regimens, and improving the ability to anticipate treatment response is described as a high priority.
How is this program positioned relative to prior DoD and VA efforts on PTSD?
The opportunity acknowledges extensive prior DoD and VA research investments supporting PTSD treatments, and it positions the consortium as a way to accelerate progress by coordinating expertise and resources to improve prognostics, advance therapeutic options, and mitigate negative long-term consequences of traumatic exposure.
Is this opportunity linked to any external recommendations or reports?
Yes. The program is framed as a direct response to recommendations highlighted in a DoD/VA sponsored Institute of Medicine report on treatment for PTSD in military and veteran populations, signaling an intent to align funded work with identified gaps in evidence and clinical impact.
What type of award mechanism is used for this opportunity?
It was issued as a discretionary cooperative agreement.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is W81XWH 12 PHTBI CAP.
What category does this opportunity fall under?
It falls under the Science and Technology and other Research and Development category.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA 12.420, Military Medical Research and Development.
Which agency is listed as the sponsoring agency?
The Department of the Army, through USAMRAA, is the sponsoring agency.
How many awards were anticipated?
The opportunity anticipated a single award.
What was the estimated total funding level?
The estimated total funding level was $20,336,000.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
Who was eligible to apply?
Eligibility was listed as unrestricted, meaning it was broadly open to different types of applicant organizations, subject to any additional eligibility clarifications contained in the full announcement.
When was the opportunity posted?
The posting date was September 6, 2012.
What was the closing date for applications?
The original and current closing date was January 4, 2013.
When was the opportunity archived?
The archive date was February 3, 2013.
Who should applicants contact for access issues related to the full announcement?
For access issues related to the full announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
What outcomes is the consortium expected to drive, based on the announcement?
Based on the description provided, the consortium is expected to generate knowledge that clarifies factors influencing recovery versus persistent impairment, improve prediction of chronic PTSD risk and treatment response, and support development of better diagnostics, novel treatments, and rehabilitative strategies to reduce long-term consequences of traumatic exposure.
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