Drug Abuse, Risky Decision Making and HIV/AIDS (R01) | Apply Online

Frequently Asked Questions (FAQs)

What is PAS 07 324?

PAS 07 324 is an NIH Funding Opportunity Announcement (FOA) titled "Drug Abuse, Risky Decision Making and HIV/AIDS (R01)." It supports research that explains how drug use and addiction-related processes shape decision making about high-risk sexual behavior in ways that increase the likelihood of acquiring or transmitting HIV.

What is the main goal of this funding opportunity?

The main goal is to move beyond simply documenting that substance use and HIV risk co-occur. NIH is seeking theory-driven, model-based research that clarifies the decision processes involved in choosing to engage in risky sexual behavior, with drug abuse/addiction mechanisms examined as key drivers of those decisions.

What topic must be the central focus of proposed projects?

The decision to engage in risky sexual behavior must remain the clear, central focus. Projects are expected to study drug abuse or addiction mechanisms as factors influencing those decisions, rather than treating HIV risk as a secondary outcome.

What kind of research approach is NIH emphasizing here?

NIH emphasizes interdisciplinary, model-driven, hypothesis-driven research. Competitive projects would typically propose a coherent conceptual or computational model and pair it with data collection and/or experiments that can validate, refine, or falsify the model.

What disciplines and methods are encouraged?

The FOA encourages integrating perspectives and methods from fields such as psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling.

Are modeling and testable predictions expected?

Yes. The announcement specifically encourages modeling approaches that generate testable predictions and can directly guide empirical studies.

What are examples of models or constructs that may fit the FOA's intent?

Examples mentioned include models of reward valuation, impulsivity, delay discounting, social and contextual influences, and neurocognitive control, especially where these constructs are used to explain risky sexual decision making in the context of drug use or addiction.

What funding mechanism does PAS 07 324 use?

PAS 07 324 uses the NIH Research Project Grant (R01) mechanism, which typically supports larger, multi-year research projects with substantial scope.

Are there related opportunities with the same scientific scope?

Yes. This FOA was published in parallel with two companion announcements of identical scientific scope that use smaller mechanisms: PAS 07 325 (R21) and PAS 07 326 (R03).

How is the R01 (PAS 07 324) different from the companion R21 and R03 announcements?

While the scientific goals are aligned across PAS 07 324 (R01), PAS 07 325 (R21), and PAS 07 326 (R03), PAS 07 324 is specifically intended for full research projects that require more time, resources, and infrastructure than exploratory (R21) or small-scale (R03) studies.

How much funding was available?

For fiscal year 2007, the estimated total funding available for projects under this FOA was $2,000,000.

How many awards did NIH anticipate making?

NIH anticipated making anywhere from five to 25 awards across the set of related announcements, with a reasonable estimate of roughly 10 to 12 grants supported.

Were there multiple deadlines to apply?

Yes. The announcement lists multiple receipt dates, meaning applications could be accepted on more than one deadline rather than having a single closing date.

Is this funding opportunity still active?

No. The opportunity was later archived on February 2, 2010.

When was the full announcement posted?

The full announcement was posted on February 2, 2007.

Who can apply for PAS 07 324?

Eligibility is broad and includes a wide range of organization types across the public, private, nonprofit, and academic sectors, as well as foreign institutions and eligible U.S. federal agencies.

Are nonprofit organizations eligible?

Yes. Eligible applicants include nonprofits with and without 501(c)(3) status, including faith-based and community-based organizations.

Are for-profit organizations eligible?

Yes. For-profit organizations (other than small businesses) are eligible, and small businesses are also listed as eligible applicants.

Are colleges and universities eligible?

Yes. Public and private institutions of higher education are eligible.

Are government entities eligible to apply?

Yes. Eligible government entities include city/township governments, county governments, state governments, special district governments, independent school districts, and tribal governments including federally recognized tribal governments.

Are public housing authorities eligible?

Yes. Public housing authorities/Indian housing authorities are included as eligible applicants.

Are foreign institutions eligible to apply?

Yes. The announcement states that foreign institutions are eligible to apply.

Can U.S. federal government agencies apply?

Yes. The announcement states that eligible agencies of the U.S. Federal Government can apply.

Is cost sharing or matching required?

No. The opportunity states there is no cost-sharing or matching requirement.

What kind of grant is this administratively?

This is a discretionary grant opportunity under the National Institutes of Health.

What CFDA program is associated with this opportunity?

The program classification is tied to CFDA 93.279, Drug Abuse and Addiction Research Programs.

Where can applicants find the detailed funding notice?

The detailed funding notice is available via the NIH Grants Guide webpage referenced in the opportunity link provided in the announcement.

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, NIH directs applicants to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.