Opportunity Information: Apply for PAS 07 325
Apply for PAS 07 325
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Drug Abuse, Risky Decision Making and HIV/AIDS (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 5, 2008 and posted on Feb 2, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments Independent school districts Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Special district governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education County governments Small businesses.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Drug Abuse, Risky Decision Making and HIV/AIDS (R21) funding opportunity (Funding Opportunity Number PAS-07-325) is an NIH discretionary grant announcement designed to push forward early-stage, exploratory research on a specific public health problem: how drugs of abuse and addiction-related processes shape decision making around high-risk sexual behavior in ways that increase the likelihood of acquiring or transmitting HIV. The central requirement is that the proposed study must focus primarily and explicitly on the decision process behind risky sexual behavior, not just on drug use or HIV risk in general. In other words, drug abuse or addiction is treated as a key influence on decision making, and the scientific core of the project is to understand, explain, and ideally predict the choices that lead to sexual risk.
A major theme of the announcement is interdisciplinarity. NIH is signaling that progress on this topic is likely to come from combining methods and theories across fields such as psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling. Applicants are encouraged to propose hypothesis-driven studies, including modeling approaches that can generate testable predictions and guide empirical work. This emphasis suggests NIH is looking for projects that go beyond descriptive correlations and instead tackle mechanisms: for example, how intoxication, withdrawal, craving, reward sensitivity, impulsivity, social context, or perceived risk and payoff alter sexual decision making under uncertainty or in emotionally charged situations.
The mechanism of support is the NIH Exploratory/Developmental R21, which is commonly used for projects that are innovative, higher-risk, or still in an early phase where preliminary data may be limited, but where the ideas and approach are strong and could open up new lines of research. This R21 announcement is part of a coordinated set of opportunities with the same scientific scope offered under additional mechanisms: an R01 version (PA-07-324) for more mature, full-scale projects, and an R03 version (PA-07-326) for smaller, more limited efforts. That structure gives applicants multiple entry points depending on readiness and scale, while keeping the scientific priorities consistent.
In terms of funding, NIH estimated about $2,000,000 in total funds available for fiscal year 2007 for projects considered appropriate under this announcement. The award ceiling is listed as $200,000. NIH anticipated that, across the related mechanisms supported by the three parallel announcements, the number of awards could range broadly from as few as five to as many as 25, with a reasonable expectation of roughly 10 to 12 grants funded. The posting date was February 2, 2007, and the opportunity used multiple receipt dates (meaning there were several submission deadlines rather than one single closing date). The archive date is February 2, 2010.
Eligibility is broad and includes a wide range of domestic applicants such as state, county, and local governments; public and private institutions of higher education; nonprofits (including those with and without 501(c)(3) status); public housing authorities and Indian housing authorities; tribal governments and other tribal organizations; special district governments; independent school districts; for-profit organizations other than small businesses; and small businesses. The eligibility notes also clarify that foreign institutions are eligible to apply, eligible federal agencies may apply, and faith-based or community-based organizations may apply as well. The program is listed under CFDA 93.279 (Drug Abuse and Addiction Research Programs), and there is no cost sharing or matching requirement.
Overall, this FOA is aimed at generating new, testable insights into the pathways linking substance use and addiction to sexual risk-taking decisions relevant to HIV transmission. Successful applications would be expected to keep risky sexual decision making as the clear centerpiece, while using interdisciplinary tools, theory, and possibly computational or behavioral modeling to explain how drug-related states and environments shift choices in real-world contexts. The full announcement is available via NIH at http://grants.nih.gov/grants/guide/pa-files/PAS-07-325.html, and technical issues accessing the announcement are directed to the NIH Office of Extramural Research (OER) webmaster.
Frequently Asked Questions (FAQs)
What is the funding opportunity title and number?
The opportunity is titled Drug Abuse, Risky Decision Making and HIV/AIDS (R21). The NIH Funding Opportunity Number is PAS-07-325.
What is the main purpose of this FOA?
This NIH discretionary grant announcement supports early-stage, exploratory research on how drugs of abuse and addiction-related processes influence decision making around high-risk sexual behavior in ways that increase the likelihood of acquiring or transmitting HIV. The scientific center of the project must be understanding the decision process behind risky sexual behavior.
What must the proposed study focus on to be responsive?
To be responsive, the proposed study must focus primarily and explicitly on the decision-making process behind risky sexual behavior. Drug abuse/addiction should be treated as a key influence on decision making, but the project should not be framed mainly as a general drug-use study or a general HIV-risk study.
Does the FOA support projects that are only descriptive or correlational?
The FOA emphasizes moving beyond descriptive correlations. Applicants are encouraged to propose hypothesis-driven work that addresses mechanisms and, where appropriate, uses modeling approaches that produce testable predictions to guide empirical research.
What kinds of disciplines and approaches are encouraged?
Interdisciplinary projects are a major theme. NIH highlights approaches that combine methods and theories from areas such as psychology, economics, anthropology, sociology, decision sciences, neuroscience, and computational modeling.
What types of mechanisms or factors does NIH suggest studying?
The FOA signals interest in mechanism-focused questions such as how intoxication, withdrawal, craving, reward sensitivity, impulsivity, social context, perceived risk, and perceived payoff may alter sexual decision making under uncertainty or emotionally charged situations.
What grant mechanism is used for this opportunity?
This announcement uses the NIH Exploratory/Developmental R21 mechanism.
Why is the R21 mechanism a good fit for this topic?
The R21 is commonly used for innovative, higher-risk, early-phase projects, including those where preliminary data may be limited but the idea and approach are strong and could open new lines of research.
Are there related funding opportunities with the same scientific scope?
Yes. NIH offered parallel opportunities with the same scientific scope under other mechanisms: an R01 version (PA-07-324) for more mature full-scale projects, and an R03 version (PA-07-326) for smaller, more limited efforts.
How much funding is available under this FOA?
NIH estimated about $2,000,000 in total funds available for fiscal year 2007 for projects considered appropriate under this announcement.
What is the award ceiling?
The listed award ceiling is $200,000.
How many awards did NIH anticipate making?
Across the three related mechanisms (R21/R01/R03), NIH indicated the number of awards could range from about 5 to 25, with a reasonable expectation of roughly 10 to 12 grants funded.
When was the FOA posted, and when was it archived?
The posting date was February 2, 2007. The archive date is February 2, 2010.
Was there a single deadline, or multiple receipt dates?
The opportunity used multiple receipt dates, meaning there were several submission deadlines rather than a single closing date.
Who is eligible to apply?
Eligibility is broad and includes many domestic applicant types, including:
- State, county, and local governments
- Public and private institutions of higher education
- Nonprofits (with and without 501(c)(3) status)
- Public housing authorities and Indian housing authorities
- Tribal governments and other tribal organizations
- Special district governments
- Independent school districts
- For-profit organizations (other than small businesses)
- Small businesses
Are foreign institutions allowed to apply?
Yes. The eligibility notes indicate that foreign institutions are eligible to apply.
Can federal agencies apply?
Yes. The eligibility notes indicate that eligible federal agencies may apply.
Are faith-based or community-based organizations eligible?
Yes. The eligibility notes specify that faith-based or community-based organizations may apply.
Is cost sharing or matching required?
No. The FOA states that there is no cost sharing or matching requirement.
What CFDA program is this opportunity associated with?
The program is listed under CFDA 93.279 (Drug Abuse and Addiction Research Programs).
Where can applicants find the full FOA text?
The full announcement is available through NIH at: http://grants.nih.gov/grants/guide/pa-files/PAS-07-325.html
Who should be contacted for technical issues accessing the announcement?
Technical issues accessing the announcement are directed to the NIH Office of Extramural Research (OER) webmaster.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAS 07 325) also looked into and applied for these:
| Funding Opportunity |
|---|
| Academic Industrial Partnerships for Development and Validation of In Vivo Imaging Systems and Methods for Cancer Investigations (R01) Apply for PAR 07 214 Funding Number: PAR 07 214 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NIDA Research Education Grants in Drug Abuse and Addiction (R25) Apply for PAR 07 221 Funding Number: PAR 07 221 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroscience Research on Drug Abuse (R01) Apply for PA 07 226 Funding Number: PA 07 226 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroscience Research on Drug Abuse (R21) Apply for PA 07 227 Funding Number: PA 07 227 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Neuroscience Research on Drug Abuse(R03) Apply for PA 07 228 Funding Number: PA 07 228 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Collaborative Clinical Trials in Drug Abuse (R01) Apply for PAR 07 232 Funding Number: PAR 07 232 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R01) Apply for PA 07 329 Funding Number: PA 07 329 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21) Apply for PA 07 331 Funding Number: PA 07 331 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) Apply for PA 07 330 Funding Number: PA 07 330 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for the Treatment of Amphetamine and Amphetamine Like Related Disorders (R01) Apply for PA 07 333 Funding Number: PA 07 333 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for the Treatment of Amphetamine and Amphetamine Like Related Disorders (R21) Apply for PA 07 334 Funding Number: PA 07 334 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Development of Animal Models and Related Biological Materials For Research (R21) Apply for PA 07 336 Funding Number: PA 07 336 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Treatment Adherence Research (R01) Apply for PA 07 338 Funding Number: PA 07 338 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Treatment Adherence Research (R03) Apply for PA 07 339 Funding Number: PA 07 339 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Treatment Adherence Research (R21) Apply for PA 07 340 Funding Number: PA 07 340 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Developing And Improving Institutional Animal Resources (G20) Apply for PAR 07 342 Funding Number: PAR 07 342 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| AIDS Science Track Award for Research Transition (R03) Apply for PA 07 349 Funding Number: PA 07 349 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Bioengineering and Obesity (R01) Apply for PA 07 354 Funding Number: PA 07 354 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Improving Heart Failure Disease Management (R01) Apply for PA 07 355 Funding Number: PA 07 355 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Clinical Cancer Therapy and Prevention Research (R01) Apply for PA 07 356 Funding Number: PA 07 356 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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