Opportunity Information: Apply for PAR 10 276

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Sep 2, 2010 and posted on Sep 2, 2010.
  • Applicants must submit their applications by Sep 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) County governments City or township governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Special district governments For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession State agricultural experiment stations National Laboratories
Apply for PAR 10 276

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Opportunity Summary:

The Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01) opportunity (Funding Opportunity Number PAR-10-276) is an interagency funding announcement that brings together the National Institutes of Health (NIH) and the U.S. Department of Agriculture (USDA) to support research that intentionally serves two goals at once: advancing human health and improving agriculture. It is jointly issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Heart, Lung, and Blood Institute (NHLBI), and USDA's National Institute of Food and Agriculture (NIFA). The central idea is to fund high-quality basic and translational studies that use agriculturally important domestic species (farm animals) as research models, where the work is clearly and credibly relevant to both biomedical science and food/animal agriculture.

A defining feature of this program is its emphasis on comparative medicine and on refining and selecting farm animal models that more closely mimic human development, physiology, and disease processes than traditional laboratory species might in certain contexts. The FOA highlights the use of these models to better understand disease origins and mechanisms, and also to improve assisted reproduction efficiencies. In other words, applicants are expected to design studies where farm animal research can help answer meaningful questions about human health and disease, while also generating outcomes that matter for animal health, animal production, or product quality in agriculture. The envisioned end results include fundamental discoveries that inform human medicine alongside tangible advances that strengthen food animal production systems.

The funding mechanism is the NIH Research Project Grant (R01), which generally supports discrete, investigator-driven research projects of significant scope and scientific depth. Awards under this announcement depend on available funds and on the number and quality of applications received, so there is no guaranteed set-aside amount or fixed number of awards stated in the summarized text. A notable operational point is that NIH and USDA NIFA intend to independently fund proposals, reinforcing the expectation that projects align with mission priorities of both the biomedical and agricultural agencies rather than being purely one or the other.

In terms of who can apply, eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants span public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), small businesses, for-profit organizations (other than small businesses), and multiple levels of government (state, county, city/township, special districts), as well as public housing authorities/Indian housing authorities. The eligibility section also explicitly includes a range of institutions and organizations such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), other Indian/Native American tribal governments and organizations, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, state agricultural experiment stations, national laboratories, and foreign (non-U.S.) entities. The opportunity does not require cost sharing or matching.

Administratively, this is a discretionary grant opportunity categorized under Health, Income Security and Social Services, and it is associated with CFDA numbers 93.859 (Biomedical Research and Research Training) and 93.865 (Child Health and Human Development Extramural Research). The FOA was posted on September 2, 2010, with an original and current closing date of September 20, 2012, and it was archived on October 21, 2012, meaning it is no longer open for new submissions under that specific announcement. The sponsoring agency listed is NIH, and the full announcement historically was accessible through the NIH Grants Guide (linked in the source data). For access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster.

FAQs: Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01) (PAR-10-276)

What is the PAR-10-276 funding opportunity?

PAR-10-276 is an interagency funding announcement that brought together the National Institutes of Health (NIH) and the U.S. Department of Agriculture (USDA) to support research designed to accomplish two goals at the same time: (1) advance human health and (2) improve agriculture. The program focuses on studies that use agriculturally important domestic species (farm animals) as research models and that are clearly relevant to both biomedical science and food/animal agriculture.

What is the official program name?

The opportunity is titled: Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Species (R01).

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PAR-10-276.

Which agencies and institutes are involved?

This is jointly issued by NIH and USDA. The participating NIH institutes listed are the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung, and Blood Institute (NHLBI). On the USDA side, the participating agency is the National Institute of Food and Agriculture (NIFA).

What is the main purpose or central idea of this program?

The central idea is to fund high-quality basic and translational research that intentionally uses farm animal models to generate outcomes that matter in both domains: improved understanding of human health and disease, and practical or scientific advances that strengthen food/animal agriculture (such as animal health, animal production, or product quality).

What does "dual purpose with dual benefit" mean in practice?

It means an application is expected to be designed so that the research is credibly important to human biomedical science and also produces meaningful benefits for agriculture. Projects that are primarily biomedical with minimal agricultural relevance (or primarily agricultural with minimal biomedical relevance) would not match the stated intent described in the opportunity summary.

What types of research does the FOA emphasize?

The FOA emphasizes comparative medicine approaches and the refinement and selection of farm animal models that, in some contexts, may more closely mimic human development, physiology, and disease processes than traditional laboratory species. It highlights using these models to better understand disease origins and mechanisms and to improve assisted reproduction efficiencies.

What kinds of animals are expected to be used as models?

The program specifically emphasizes agriculturally important domestic species, described as farm animals, used as research models.

Is this basic research, translational research, or both?

Both. The summary explicitly describes support for basic and translational studies, as long as they align with the dual biomedical and agricultural goals.

What funding mechanism does this opportunity use?

The funding mechanism is the NIH Research Project Grant (R01), which generally supports discrete, investigator-driven research projects of significant scope and scientific depth.

Is there a guaranteed amount of funding or a set number of awards?

No. Based on the information provided, awards depend on available funds and on the number and quality of applications received. The summarized text does not state a fixed set-aside amount or a fixed number of awards.

How does funding work between NIH and USDA NIFA?

NIH and USDA NIFA intend to independently fund proposals. This reinforces the expectation that proposed projects align with the mission priorities of both biomedical and agricultural agencies, rather than being exclusively focused on only one domain.

Who is eligible to apply?

Eligibility is broad and includes many domestic and non-domestic organization types. Eligible applicants include public and private institutions of higher education; nonprofits (with and without 501(c)(3) status); small businesses; for-profit organizations (other than small businesses); and multiple levels of government (state, county, city/township, and special districts), including public housing authorities/Indian housing authorities.

Are minority-serving institutions and tribal entities included in eligibility?

Yes. The eligibility section explicitly includes organizations such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), other Indian/Native American tribal governments and organizations, and additional regional organizations and U.S. territories or possessions.

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are explicitly included in the eligibility description.

Are foreign (non-U.S.) entities eligible to apply?

Yes. The eligibility description explicitly includes foreign (non-U.S.) entities.

Are state agricultural experiment stations and national laboratories eligible?

Yes. State agricultural experiment stations and national laboratories are explicitly listed among eligible institution types.

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching.

What is the grant category or type of opportunity described?

It is described as a discretionary grant opportunity and is categorized under Health, Income Security and Social Services.

Which CFDA numbers are associated with this opportunity?

The opportunity is associated with CFDA 93.859 (Biomedical Research and Research Training) and CFDA 93.865 (Child Health and Human Development Extramural Research).

When was the FOA posted?

The FOA was posted on September 2, 2010.

What was the closing date for applications?

The original and current closing date listed is September 20, 2012.

Is this opportunity still open?

No. It was archived on October 21, 2012, which indicates it is no longer open for new submissions under that specific announcement.

Who is listed as the sponsoring agency?

The sponsoring agency listed is NIH.

Where was the full announcement historically posted?

The full announcement historically was accessible through the NIH Grants Guide (as referenced in the source data summary).

Who should be contacted for access issues related to the announcement?

For access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster.

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