Opportunity Information: Apply for RFA GM 11 008
Apply for RFA GM 11 008
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Protein Structure InitiativeBiology Materials Repository (PSIBiology MR) (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Sep 2, 2010 and posted on Sep 2, 2010.
- Applicants must submit their applications by Nov 3, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Small businesses For profit organizations other than small businesses County governments City or township governments Independent school districts Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Protein Structure Initiative-Biology Materials Repository (PSI-Biology MR) funding opportunity (RFA-GM-11-008) is a National Institutes of Health (NIH), National Institute of General Medical Sciences (NIGMS) cooperative agreement intended to support a single, centralized repository that serves the PSI-Biology program. The main goal is to maintain and further develop the PSI-Biology Materials Repository so it can reliably collect, curate, store, and distribute key biological materials generated by PSI-Biology Centers, especially the vectors and clones produced during protein structure determination efforts. By acting as the program's hub for these research tools, the repository is meant to make PSI-Biology outputs broadly accessible to the wider scientific community, helping other researchers reproduce results, build on prior work, and accelerate follow-on discoveries.
Functionally, the MR is positioned as the operational backbone for sharing PSI-Biology-generated reagents. The solicitation emphasizes that the repository is not simply a storage facility, but an active distribution and access-enabling resource: it must receive materials from PSI-Biology Centers, maintain them under appropriate conditions, keep them organized and traceable, and provide mechanisms for distributing them to external investigators. The underlying public benefit is that PSI-Biology investments yield tangible, reusable research resources, rather than remaining confined to the originating laboratories.
This opportunity uses the U01 cooperative agreement mechanism, which signals substantial scientific or programmatic involvement by NIH staff compared with a standard grant. The awardee is expected to work closely with NIH and the broader PSI-Biology leadership structure. In particular, the funded group will become part of the PSI-Biology Network Steering Committee and will collaborate with other investigators and NIH staff to help manage the overall PSI-Biology initiative. In practice, that implies ongoing coordination, shared planning, and alignment with network priorities, not just independent operation of a repository.
NIGMS anticipated making one award through this announcement, with up to $1.5 million per year in annual total costs available for the project. There is no cost sharing or matching requirement. The funding activity category is health, under CFDA 93.859 (Biomedical Research and Research Training), reflecting the biomedical research infrastructure role of the repository.
Eligibility is broad and includes many organization types across the public, private, nonprofit, and educational sectors. Eligible applicants listed include small businesses, for-profit organizations (including those other than small businesses), nonprofits (both 501(c)(3) and non-501(c)(3), with the caveat "other than institutions of higher education" as stated in the listing), private and public institutions of higher education, and a wide range of governmental entities (state, county, city/township, special districts), as well as public housing authorities/Indian housing authorities. The notice also calls out additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, faith-based or community-based organizations, eligible federal agencies, and U.S. territories or possessions, along with Native American tribal governments and tribal organizations (both federally recognized and other-than-federally recognized, as specified). Overall, the eligibility language indicates the program is focused less on institutional type and more on the applicant's capacity to operate a high-quality, centralized biological materials repository in close coordination with the PSI-Biology network.
Key dates in the posting show it was posted and created on September 2, 2010, with an original and current closing date of November 3, 2010, and an archive date of December 4, 2010. The sponsoring agency is NIH, and the full announcement was made available through the NIH Grants Guide (link provided in the source). For technical issues accessing the announcement, the listed point of contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the Protein Structure Initiative-Biology Materials Repository (PSI-Biology MR) funding opportunity?
It is an NIH National Institute of General Medical Sciences (NIGMS) funding opportunity (RFA-GM-11-008) to support a single, centralized Protein Structure Initiative-Biology Materials Repository (PSI-Biology MR) that serves the PSI-Biology program.
Which NIH institute is sponsoring this opportunity?
The sponsoring institute is the National Institute of General Medical Sciences (NIGMS) within the National Institutes of Health (NIH).
What is the main purpose of the PSI-Biology Materials Repository?
The main purpose is to maintain and further develop the PSI-Biology Materials Repository so it can reliably collect, curate, store, and distribute key biological materials generated by PSI-Biology Centers, particularly vectors and clones produced during protein structure determination efforts.
What kinds of materials is the repository expected to handle?
The repository is expected to handle key biological materials generated by PSI-Biology Centers, with specific emphasis on vectors and clones produced during protein structure determination efforts.
Is the repository intended to be just a storage facility?
No. The solicitation emphasizes that the repository is not simply a storage facility. It is intended to be an active distribution and access-enabling resource that receives materials, maintains them under appropriate conditions, keeps them organized and traceable, and distributes them to external investigators.
Who is the repository meant to serve?
The repository is meant to serve the PSI-Biology program by acting as a centralized hub for PSI-Biology-generated research tools, while also making PSI-Biology outputs broadly accessible to the wider scientific community.
What public benefit is expected from funding this repository?
The stated public benefit is that PSI-Biology investments yield tangible, reusable research resources that are broadly accessible, enabling other researchers to reproduce results, build on prior work, and accelerate follow-on discoveries.
What funding mechanism is used for this opportunity?
This opportunity uses the U01 cooperative agreement mechanism.
What does the U01 cooperative agreement mechanism imply for the awardee?
The U01 mechanism signals substantial scientific or programmatic involvement by NIH staff compared with a standard grant. The awardee is expected to work closely with NIH and the broader PSI-Biology leadership structure, implying ongoing coordination, shared planning, and alignment with network priorities.
How many awards did NIGMS anticipate making under this announcement?
NIGMS anticipated making one award through this announcement.
What is the anticipated funding level?
Up to $1.5 million per year in annual total costs was available for the project.
Is there a cost sharing or matching requirement?
No. The announcement states there is no cost sharing or matching requirement.
What is the funding activity category and CFDA number?
The funding activity category is health. The CFDA number is 93.859, listed as Biomedical Research and Research Training.
What role is the funded repository expected to play within the PSI-Biology program?
Functionally, the repository is positioned as the operational backbone for sharing PSI-Biology-generated reagents. It must receive materials from PSI-Biology Centers, maintain them properly, keep them organized and traceable, and provide mechanisms for distributing them to external investigators.
Is the awardee expected to participate in PSI-Biology leadership or governance?
Yes. The funded group will become part of the PSI-Biology Network Steering Committee and will collaborate with other investigators and NIH staff to help manage the overall PSI-Biology initiative.
Who is eligible to apply?
Eligibility is broad and includes small businesses; for-profit organizations (including those other than small businesses); nonprofit organizations (both 501(c)(3) and non-501(c)(3), with the listing caveat "other than institutions of higher education"); private and public institutions of higher education; and many governmental entities (state, county, city/township, special district), as well as public housing authorities/Indian housing authorities.
Are specific institution types or communities explicitly included in the eligibility list?
Yes. The eligibility list specifically calls out Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, Native American tribal governments (federally recognized and other-than-federally recognized), and tribal organizations (federally recognized and other-than-federally recognized).
Does the opportunity focus more on organization type or operational capability?
Based on the eligibility language provided, the opportunity appears focused less on institutional type and more on the applicant's capacity to operate a high-quality, centralized biological materials repository in close coordination with the PSI-Biology network.
What are the key dates for this funding opportunity?
The posting shows it was posted and created on September 2, 2010. The original and current closing date is November 3, 2010. The archive date is December 4, 2010.
Where was the full announcement made available?
The full announcement was made available through the NIH Grants Guide (a link was provided in the source information).
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the point of contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the opportunity identifier?
The funding opportunity is identified as RFA-GM-11-008 for the PSI-Biology Materials Repository (PSI-Biology MR).
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