Opportunity Information: Apply for PA 16 273
Apply for PA 16 273
- The HHS-NIH11 in the education, environment, health sector is offering a public funding opportunity titled "Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.361,.
- This funding opportunity was created on May 19, 2016 and posted on May 19, 2016.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21) funding opportunity (PA-16-273) is a discretionary NIH grant program under HHS (listed here as HHS-NIH11) designed to spark interdisciplinary, exploratory research on how environmental exposures affect health in places that are not typically the focus of traditional environmental health studies. The central idea is to improve health promotion, prevent or limit symptoms and disease, and reduce health disparities across the entire lifespan for people who live in, receive care in, or regularly spend time in community-based or residential settings where exposures may be overlooked. The FOA places a strong emphasis on advancing nursing science by focusing on practical risk identification and symptom management strategies that can be used by individuals, families, and communities, including prevention-oriented behaviors and actions that help maintain health and prevent disease.
A key feature of this opportunity is its focus on "non-traditional settings," meaning real-world environments where vulnerable populations spend substantial time and may encounter a mix of chemical and non-chemical stressors. Examples listed in the announcement include community centers; pre-school and non-traditional school environments such as churches, daycare, home-based schools, dormitories, alternative schools, and playgrounds; child and older adult foster care facilities; older adult day care facilities; half-way homes; and assisted living and long-term care facilities. By encouraging work in these settings, the FOA aims to fill gaps where exposure monitoring, mitigation strategies, and symptom prevention efforts may lag behind what is commonly done for workplaces, outdoor air monitoring stations, or conventional clinical environments.
The health concerns highlighted in the description point to both specific diseases and broader exposure scenarios. The FOA references environmental pollutants and toxins that can contribute to health risks, symptoms, and conditions such as lower respiratory disease, chronic obstructive pulmonary disease (COPD), and cardiovascular disease. It also calls attention to complex environmental exposures, including situations where chemical exposures may be intensified or complicated by non-chemical stressors encountered in community settings (for example, stress, crowding, noise, psychosocial strain, or other contextual stressors that can interact with pollution to worsen outcomes). Another emphasis is on sensitive developmental windows and physiological vulnerability, including impacts on the function of organs and systems of the fetus, child, and adolescent, reflecting a lifespan approach rather than limiting the research to a single age group.
From a research approach standpoint, the announcement encourages interdisciplinary teams and exploratory studies consistent with the R21 mechanism, which is commonly used to support early-stage, proof-of-concept, or high-potential ideas that can later be expanded. Within that exploratory frame, the FOA signals interest in work that does more than identify hazards; it also values projects that improve risk identification in practical settings and translate findings into symptom management and prevention strategies. The description explicitly notes prevention and behavior changes, implying that investigators might examine feasible interventions or decision-support tools that can be adopted by families, caregivers, community organizations, or care facilities to reduce exposure or lessen health impacts.
Administrative details in the source data indicate that this is a grant (FundingInstrumentType: Grant) spanning activity categories of education, environment, and health. The CFDA numbers associated with the opportunity are 93.113 and 93.361. The posted and created dates are May 19, 2016, and the closing date listed is September 7, 2019. The award ceiling shown in the record is $200,000. While the number of expected awards is not provided in the excerpt, the structure and ceiling suggest relatively modest, exploratory-scale projects aimed at generating actionable early evidence and setting up future, larger studies.
Eligibility is broad and includes many types of organizations that are positioned to study or intervene in community and care settings. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other applicants as allowed by additional eligibility guidance referenced in the full announcement. This broad eligibility aligns with the FOA's real-world focus, since relevant research partnerships may involve universities, health systems, community organizations, school systems, long-term care providers, tribes, and local governments working together in the same environments where exposure and health risks occur.
Overall, this FOA is centered on understanding and addressing environmental exposures where people actually spend time outside of conventional study contexts, with special attention to vulnerable groups such as children and older adults and to the cumulative nature of environmental and social stressors. The intended impact is practical and equity-focused: generate interdisciplinary evidence that supports prevention, symptom reduction, and health promotion in overlooked settings, ultimately reducing disparities and improving health outcomes across the lifespan.
Frequently Asked Questions (FAQs)
What is the Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21) opportunity?
It is a discretionary NIH grant funding opportunity under HHS (listed as HHS-NIH11) titled "Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21)." The funding opportunity announcement (FOA) is PA-16-273 and is designed to spark interdisciplinary, exploratory research on how environmental exposures affect health in real-world places that are not typically the focus of traditional environmental health studies.
What is the main goal of this FOA?
The central goal is to improve health promotion, prevent or limit symptoms and disease, and reduce health disparities across the entire lifespan by studying environmental exposures in community-based or residential settings where exposures may be overlooked.
What does "non-traditional settings" mean in this FOA?
"Non-traditional settings" refers to real-world environments where people, including vulnerable populations, spend substantial time and may face a mix of chemical and non-chemical stressors that are not commonly studied in conventional workplace monitoring, outdoor air monitoring stations, or traditional clinical environments.
What are examples of non-traditional settings mentioned in the FOA?
Examples include community centers; pre-school and non-traditional school environments (such as churches, daycare, home-based schools, dormitories, alternative schools, and playgrounds); child and older adult foster care facilities; older adult day care facilities; half-way homes; and assisted living and long-term care facilities.
What types of environmental exposures are within scope?
The FOA focuses on environmental pollutants and toxins that can contribute to health risks, symptoms, and disease, and it also highlights complex exposure scenarios in community settings that may include both chemical exposures and non-chemical stressors.
What non-chemical stressors are referenced as relevant to this research?
The FOA notes that chemical exposures may be intensified or complicated by non-chemical stressors encountered in community settings, such as stress, crowding, noise, psychosocial strain, or other contextual stressors that can interact with pollution to worsen health outcomes.
What health conditions and outcomes are highlighted?
The FOA references health risks, symptoms, and conditions including lower respiratory disease, chronic obstructive pulmonary disease (COPD), and cardiovascular disease. It also emphasizes symptom prevention and reduction as part of the intended impact.
Does the FOA take a lifespan approach?
Yes. The description emphasizes sensitive developmental windows and physiological vulnerability, including impacts on the function of organs and systems of the fetus, child, and adolescent, and it frames the work as relevant across the entire lifespan rather than limited to one age group.
Why does the FOA emphasize vulnerable populations?
Because vulnerable groups may spend substantial time in community-based or residential settings where exposure monitoring, mitigation strategies, and symptom prevention efforts may be less developed, contributing to avoidable health impacts and health disparities.
What is the R21 mechanism intended to support in this program?
The R21 mechanism is positioned here to support exploratory studies, early-stage research, proof-of-concept work, or other high-potential ideas that can later be expanded into larger studies.
Is the FOA limited to identifying hazards, or does it support action-oriented work?
It signals interest in more than hazard identification. The FOA values projects that improve practical risk identification in real-world settings and translate findings into symptom management and prevention strategies.
What kinds of practical strategies does the FOA emphasize?
The FOA emphasizes practical risk identification and symptom management strategies that can be used by individuals, families, and communities, including prevention-oriented behaviors and actions that help maintain health and prevent disease.
Does the FOA encourage interdisciplinary research teams?
Yes. A key intent is to spark interdisciplinary, exploratory research, consistent with the complexity of environmental exposures and the mix of chemical and non-chemical stressors in community and residential environments.
How does this FOA relate to nursing science?
The FOA places strong emphasis on advancing nursing science by focusing on practical approaches to risk identification and symptom management, and on prevention-oriented behaviors and actions that can be implemented by individuals, families, and communities.
What is the funding instrument type for this opportunity?
The funding instrument type is a Grant.
What activity categories are associated with this opportunity?
The activity categories listed are education, environment, and health.
What CFDA numbers are associated with this FOA?
The CFDA numbers associated with the opportunity are 93.113 and 93.361.
What is the award ceiling listed in the record?
The award ceiling shown is $200,000.
Are the number of expected awards provided in the excerpt?
No. The excerpt notes that the number of expected awards is not provided.
When was this opportunity posted and created?
The posted and created dates are May 19, 2016.
What is the closing date listed in the provided information?
The closing date listed is September 7, 2019.
Who is eligible to apply?
Eligibility is broad and includes: state governments; county governments; city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other applicants as allowed by additional eligibility guidance referenced in the full announcement.
Does the FOA support partnerships across community organizations and institutions?
The broad eligibility and real-world focus align with partnerships that may involve universities, health systems, community organizations, school systems, long-term care providers, tribes, and local governments working together in the settings where exposures and related health risks occur.
What gap is this FOA trying to address compared to traditional environmental health studies?
It aims to fill gaps in settings where exposure monitoring, mitigation strategies, and symptom prevention may lag behind what is commonly done in workplaces, at outdoor air monitoring stations, or in conventional clinical environments.
What is the intended impact of projects funded under this FOA?
The intended impact is practical and equity-focused: generate interdisciplinary evidence that supports prevention, symptom reduction, and health promotion in overlooked settings, ultimately reducing disparities and improving health outcomes across the lifespan.
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