Opportunity Information: Apply for PA 11 230

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Epidemiology of Drug Abuse (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Jun 11, 2014 and posted on Jun 16, 2011.
  • Applicants must submit their applications by Sep 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Special district governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses Private institutions of higher education State governments City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Epidemiology of Drug Abuse (R01) funding opportunity (PA 11-230) is a National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) research grant announcement that supports investigator-initiated projects using the R01 mechanism. The main goal is to expand scientific understanding of drug use, drug abuse, and addiction by studying how these problems arise, how they spread and change across populations, and what short- and long-term consequences they create for individuals, families, communities, and diverse demographic groups. The program is centered on epidemiology, meaning it emphasizes real-world patterns and causes of substance use behaviors and related health outcomes, rather than focusing only on clinical treatment trials or basic laboratory science.

A major emphasis of the announcement is encouraging research that looks across multiple levels of causation. In practice, that means NIDA is looking for studies that do not treat drug abuse as a single-factor issue, but instead examine how influences stack and interact across biology, development, behavior, relationships, and broader environments. Examples of the types of approaches the FOA highlights include work on gene-by-environment or gene-by-development interactions, studies that link individual risk with family or community context, and research that evaluates how social environments (such as neighborhood conditions, social networks, policy landscapes, stigma, and access to resources) shape drug use trajectories and downstream health outcomes. The announcement also explicitly values transdisciplinary projects, where teams draw on methods and perspectives from multiple fields (for example, epidemiology, genetics, psychology, sociology, economics, demography, biostatistics, data science, criminology, and public health) to generate stronger, more realistic explanations of substance use patterns.

The FOA also strongly encourages innovative and efficient use of existing resources, particularly by leveraging datasets that already exist due to prior investments by NIH and other funders. That can include secondary analyses of large surveys, cohort studies, administrative datasets, linked records, or other established data resources, as long as the proposed work uses those data creatively to answer important questions about the epidemiology and etiology of drug abuse. This emphasis signals that NIDA is receptive to proposals that are cost-conscious and can move the science forward without always requiring entirely new and expensive data collection, provided the research questions, methods, and analytic plans are rigorous and compelling.

From an administrative standpoint, this is a discretionary grant opportunity with no cost sharing or matching requirement. It is associated with CFDA number 93.279 (Drug Abuse and Addiction Research Programs). The opportunity was posted June 16, 2011, with an original and current closing date listed as September 7, 2014, and an archive date of October 7, 2014, meaning it is no longer active as written in this historical listing. Applicants are directed to the full announcement for complete details at http://grants.nih.gov/grants/guide/pa-files/PA-11-230.html, and NIH provides a general contact (the NIH Office of Extramural Research webmaster) for access or linking issues.

Eligibility is broad and includes many types of organizations that can conduct health research. Eligible applicants include public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), independent school districts, and a range of government entities such as state, county, city/township, and special district governments, as well as public housing authorities and Indian housing authorities. The announcement also specifies eligibility for a variety of mission- or community-focused institutions and organizations, including federally recognized tribal governments, other tribal organizations, Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, non-U.S. entities (foreign institutions) are also eligible to apply, and foreign components of U.S. organizations are allowed consistent with NIH policy, which opens the door to international or cross-national epidemiology projects when scientifically justified.

Overall, the opportunity is designed to fund solid, hypothesis-driven (or well-justified exploratory) epidemiologic research that clarifies how drug use and addiction emerge and operate in real populations, why risks differ across groups and settings, and what consequences follow over time. Competitive applications under this FOA would typically be expected to pair strong public health relevance with careful design and modern analytic approaches, especially when they can integrate influences across genetic, developmental, and environmental levels or make high-impact use of existing data to generate new insights into drug abuse patterns and causes.

Frequently Asked Questions (FAQs): Epidemiology of Drug Abuse (R01) - PA 11-230

What is the Epidemiology of Drug Abuse (R01) funding opportunity (PA 11-230)?

PA 11-230 is a National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) research grant announcement that supports investigator-initiated research projects using the NIH R01 mechanism. It focuses on epidemiologic research related to drug use, drug abuse, and addiction.

Which agency is offering this opportunity?

This opportunity is offered by the National Institute on Drug Abuse (NIDA), which is part of the National Institutes of Health (NIH).

What is the overall goal of this program?

The goal is to expand scientific understanding of drug use, drug abuse, and addiction by studying how these problems arise, how they spread and change across populations, and what short- and long-term consequences they create for individuals, families, communities, and diverse demographic groups.

What does "epidemiology" mean in the context of this FOA?

Here, epidemiology emphasizes real-world patterns and causes of substance use behaviors and related health outcomes in populations. The focus is on how drug use and addiction operate in real settings, rather than focusing only on clinical treatment trials or basic laboratory science.

What kinds of research topics are encouraged?

The FOA encourages research that explains how drug use, drug abuse, and addiction emerge and operate in populations, why risks differ across groups and settings, and what consequences follow over time for individuals, families, communities, and demographic groups.

Does the FOA prioritize multi-level or multi-cause explanations of drug abuse?

Yes. A major emphasis is research that looks across multiple levels of causation, examining how influences stack and interact across biology, development, behavior, relationships, and broader environments.

What are examples of the "multi-level" approaches mentioned in the FOA?

Examples highlighted include gene-by-environment or gene-by-development interactions, studies linking individual risk with family or community context, and research evaluating how social environments (such as neighborhood conditions, social networks, policy landscapes, stigma, and access to resources) shape drug use trajectories and downstream health outcomes.

Are transdisciplinary projects encouraged?

Yes. The FOA explicitly values transdisciplinary projects that combine methods and perspectives from multiple fields to produce stronger, more realistic explanations of substance use patterns.

Which disciplines or fields are specifically mentioned as relevant?

The FOA provides examples including epidemiology, genetics, psychology, sociology, economics, demography, biostatistics, data science, criminology, and public health.

Does the announcement encourage use of existing datasets?

Yes. The FOA strongly encourages innovative and efficient use of existing resources, particularly leveraging datasets created through prior investments by NIH and other funders.

What types of existing data resources are mentioned?

Examples include secondary analyses of large surveys, cohort studies, administrative datasets, linked records, or other established data resources, as long as the proposed work uses them creatively and rigorously to answer important epidemiology and etiology questions related to drug abuse.

Does using existing data mean new data collection is discouraged?

The FOA signals receptiveness to cost-conscious proposals that can move science forward without always requiring entirely new and expensive data collection, provided the questions, methods, and analytic plans are rigorous and compelling.

What grant mechanism is used for this program?

This program uses the NIH R01 research project grant mechanism and supports investigator-initiated projects.

Is this a discretionary grant, and is cost sharing required?

It is described as a discretionary grant opportunity, and there is no cost sharing or matching requirement.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs).

When was this opportunity posted and when did it close?

The listing indicates it was posted on June 16, 2011. The original and current closing date is listed as September 7, 2014, with an archive date of October 7, 2014.

Is PA 11-230 currently active?

No. Based on the closing and archive dates provided (closing date September 7, 2014; archive date October 7, 2014), this historical listing is no longer active as written.

Where can applicants find the full announcement details?

The full announcement is available at: http://grants.nih.gov/grants/guide/pa-files/PA-11-230.html.

Who is eligible to apply?

Eligibility is broad and includes many organization types that can conduct health research, including higher education institutions, nonprofit and for-profit organizations, school districts, and multiple levels of government entities. Non-U.S. entities (foreign institutions) are also eligible, and foreign components of U.S. organizations are allowed consistent with NIH policy.

Are public and private institutions of higher education eligible?

Yes. Public and private institutions of higher education are listed as eligible applicants.

Are nonprofit organizations eligible (including those without 501(c)(3) status)?

Yes. Nonprofit organizations are eligible, including nonprofits with or without 501(c)(3) status.

Are for-profit organizations eligible?

Yes. For-profit organizations are eligible, including small businesses and other for-profits.

Are government entities eligible to apply?

Yes. Eligible government entities include state, county, city/township, and special district governments, as well as public housing authorities and Indian housing authorities. Eligible federal agencies are also listed.

Are school districts eligible?

Yes. Independent school districts are included in the eligibility list.

Are tribal governments and tribal organizations eligible?

Yes. Federally recognized tribal governments and other tribal organizations are included as eligible applicants. Tribally Controlled Colleges and Universities (TCCUs) are also specifically mentioned.

Are minority-serving institutions specifically included?

Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs).

Are faith-based or community-based organizations eligible?

Yes. Faith-based or community-based organizations are explicitly listed as eligible applicants.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are included in the eligibility list.

Can foreign institutions apply?

Yes. The announcement specifies that non-U.S. entities (foreign institutions) are eligible to apply.

Are foreign components of U.S. organizations allowed?

Yes. Foreign components of U.S. organizations are allowed, consistent with NIH policy, which supports international or cross-national epidemiology projects when scientifically justified.

What kinds of outcomes or impacts is the FOA interested in?

The FOA is interested in understanding both short- and long-term consequences of drug use, drug abuse, and addiction, including impacts on individuals, families, communities, and diverse demographic groups.

What characteristics would competitive applications typically have under this FOA?

Competitive applications would typically be expected to demonstrate strong public health relevance, careful study design, and modern analytic approaches. The FOA also emphasizes projects that integrate influences across genetic, developmental, and environmental levels, and/or make high-impact use of existing data resources.

Is the FOA limited to hypothesis-driven research only?

The opportunity is described as designed to fund solid, hypothesis-driven research, or well-justified exploratory epidemiologic research, as long as it clarifies key questions about drug use and addiction in real populations.

Is there a contact listed for technical issues related to access or linking?

Yes. NIH provides a general contact (the NIH Office of Extramural Research webmaster) for access or linking issues.

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