Epigenetic Approaches in Cancer Epidemiology (R21) | Apply Online

Opportunity Summary:

The National Institutes of Health (NIH) funding opportunity PA-07-299, titled "Epigenetic Approaches in Cancer Epidemiology (R21)," is a discretionary grant program designed to push forward population-based cancer epidemiology research that focuses specifically on DNA methylation. The central goal is to encourage exploratory, early-stage studies that examine how DNA methylation markers relate to cancer risk, development, or prevention in human populations. In practical terms, this opportunity is aimed at supporting research that connects epigenetic patterns, especially methylation changes, with cancer outcomes in real-world groups of people, rather than limiting work to purely laboratory or animal-based models.

This announcement uses the NIH R21 mechanism, which is typically reserved for developmental or exploratory projects where investigators are testing new ideas, piloting approaches, or generating early evidence that can later support larger, more definitive studies. The R21 structure generally fits projects that need flexibility to explore feasibility, develop methods, or produce proof-of-concept findings in cancer epigenetics and epidemiology. NIH notes that this R21 opportunity runs in parallel with a companion announcement of the same scientific scope, PA-07-298, which uses the R01 mechanism. That parallel structure matters because it signals two pathways for similar scientific topics: the R21 route for earlier-stage or higher-risk exploratory work, and the R01 route for more mature projects that can support a full-scale research plan.

Funding levels and the number of awards are not fixed in advance. NIH makes clear that awards under this FOA depend on the availability of funds and the volume of high-quality applications received. Because proposed projects can vary widely in ambition, design, and cost (for example, pilot biomarker validation in one cohort versus a multi-cohort methods development effort), NIH expects the size and duration of awards to vary accordingly. The listing includes an award ceiling of $200,000, reflecting the typical scale of an R21 budget cap, though the exact awarded amounts can still depend on the final, approved scope and costs.

Eligibility is broad and includes a wide range of organization types. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with 501(c)(3) status (and also certain nonprofits without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses. Importantly, foreign institutions are explicitly eligible to apply, which opens the door for international population studies and global cohorts that can contribute to understanding how methylation markers and cancer patterns may differ across populations and environments.

Administratively, this opportunity is categorized under Health and Education activities and is associated with CFDA number 93.393, "Cancer Cause and Prevention Research." There is no cost sharing or matching requirement, meaning applicants are not required to provide institutional matching funds as a condition of applying or being awarded. The posting date is January 16, 2007, and the opportunity used multiple receipt dates rather than a single deadline, with applicants directed to the full announcement for the specific submission schedule. The record indicates an archive date of February 2, 2010, meaning it is no longer active as a current solicitation, but it remains useful as a reference for the NIH priorities and structure around epigenetics-focused cancer epidemiology during that period.

For applicants or readers who need the official details, NIH provided an additional information link to the full program announcement on the NIH grants site. NIH also listed contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical linking issues, which is typical for older archived announcements where formatting or URL structures may have changed over time.

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Education Health

Next opportunity: Epigenetic Approaches in Cancer Epidemiology (R01)

Previous opportunity: Information Technologies and the Internet in Health Services and Intervention Delivery (R01)

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for PA 07 299

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (PA 07 299) also looked into and applied for these:

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "PA 07 299", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.