Opportunity Information: Apply for PA 11 251
Apply for PA 11 251
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Award (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jul 10, 2014 and posted on Jul 18, 2011.
- Applicants must submit their applications by Jul 10, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal governments (Federally recognized) Special district governments County governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Small businesses State governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Award (R21) is a National Institutes of Health (NIH) discretionary grant opportunity (Funding Opportunity Number PA 11 251) designed to support early stage, innovative research on the ethical, legal, and social questions raised by human genome research. It uses the NIH R21 mechanism, which is intended for exploratory or developmental projects that test new ideas, open up new areas of inquiry, or push prior findings in fresh directions, rather than requiring a fully mature, long-term research program at the outset. The core emphasis is on studies that are novel and potentially high-impact, especially projects that examine the implications of new or rapidly evolving genomic technologies or new ways genomic information is being used in healthcare, research, public health, consumer services, and society.
The FOA specifically encourages work that addresses the real-world consequences of genomic advances, including how genomic data are generated, interpreted, shared, and applied, and how these practices affect individuals, families, communities, clinicians, researchers, institutions, and policymakers. A strong fit would be research that anticipates or responds to emerging issues, such as privacy and data governance challenges created by large-scale sequencing and data sharing, informed consent models in biobanking and secondary data use, return of results and incidental findings, equity and access concerns in genomic medicine, discrimination and stigma risks, implications for insurance and employment, legal and regulatory questions around ownership and control of genomic information, and broader social impacts such as public trust, community engagement, and responsible communication of genomic risk. The announcement also signals special interest in implications tied to novel uses of genomic information, which can include clinical decision support, direct-to-consumer testing, integration of genomic data into electronic health records, or research uses that combine genomics with other sensitive data types.
From an administrative standpoint, the opportunity is offered by NIH and aligns with multiple program areas captured by the listed CFDA numbers, including Human Genome Research (93.172) as well as research programs related to communication disorders, neuroscience, child health and human development, and aging (93.173, 93.853, 93.865, 93.866). This reflects how ELSI questions cut across many biomedical fields wherever genomic information is used. The funding instrument type is a grant, and there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of award.
In terms of budget, the award ceiling is listed as 200,000, indicating the maximum amount available under the opportunity as presented in the source data. As with many NIH announcements, the practical budget structure and allowable costs typically follow NIH policy for the R21 mechanism, and applicants would be expected to propose a scope that is appropriately sized for an exploratory project with clearly defined aims and a strong justification for why an R21 is the right fit for the proposed work.
Eligibility is broad and includes a wide range of domestic and non-domestic entities. Eligible applicants span federal recognized Native American tribal governments, tribal organizations, state and local governments (including counties, cities or townships, special district governments), independent school districts, public housing authorities/Indian housing authorities, public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), and for-profit organizations (including small businesses and other for-profits). The FOA also explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, foreign organizations, and foreign components of U.S. organizations. This broad eligibility is consistent with the ELSI mission of encouraging diverse perspectives and research settings, including studies conducted in varied communities and policy environments.
Key timeline details in the source data include an original closing date of September 7, 2014, with current closing date information and an archive date of August 10, 2014, indicating that this specific posting is now historical rather than active. The posted date is July 18, 2011, with a creation date of July 10, 2014, which likely reflects when the record was created or updated in the system hosting the listing. For full details, applicants were directed to the NIH guide page for PA 11 251, and technical assistance was available through the NIH Office of Extramural Research (OER) webmaster contact for access or linking issues.
Overall, the opportunity was meant to seed creative, forward-looking ELSI research that keeps pace with fast-moving genomic science. Competitive projects under this FOA would typically be expected to make a clear case that the question is timely, the approach is innovative, the work is feasible within an exploratory grant structure, and the results would meaningfully inform ethical practice, legal policy, institutional governance, clinical implementation, or social understanding related to genomics.
Frequently Asked Questions (FAQs)
What is this grant opportunity?
This opportunity is the Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Award (R21), an NIH discretionary grant opportunity. It is associated with Funding Opportunity Number PA 11 251 and is intended to support early-stage, innovative research on ethical, legal, and social questions raised by human genome research.
Which agency offers this funding?
The funding is offered by the National Institutes of Health (NIH).
What type of funding mechanism is used?
The opportunity uses the NIH R21 mechanism, which is designed for exploratory or developmental research projects. R21 projects typically test new ideas, open new lines of inquiry, or extend prior findings in new directions rather than requiring a fully mature long-term research program at the outset.
What is the main purpose of the ELSI R21 program described here?
The main purpose is to seed novel, potentially high-impact research that examines the ethical, legal, and social implications of genomic research, especially implications created by new or rapidly evolving genomic technologies and new ways genomic information is used across healthcare, research, public health, consumer services, and society.
What kinds of topics are a strong fit for this FOA?
The FOA encourages research on real-world consequences of genomic advances, including how genomic data are generated, interpreted, shared, and applied, and how those practices affect individuals, families, communities, clinicians, researchers, institutions, and policymakers. Examples of strong-fit topics called out in the description include:
- Privacy and data governance challenges associated with large-scale sequencing and data sharing
- Informed consent models for biobanking and secondary data use
- Return of results and incidental findings
- Equity and access in genomic medicine
- Risks of discrimination and stigma
- Implications for insurance and employment
- Legal and regulatory questions about ownership and control of genomic information
- Public trust, community engagement, and responsible communication of genomic risk
Does the FOA emphasize emerging or rapidly evolving issues?
Yes. The emphasis is on novel and timely studies, including work that anticipates or responds to emerging issues created by fast-moving advances in genomics and new uses of genomic information.
What are examples of "novel uses" of genomic information mentioned in the opportunity description?
The description highlights special interest in implications tied to novel uses of genomic information, including clinical decision support, direct-to-consumer testing, integration of genomic data into electronic health records, and research uses that combine genomics with other sensitive data types.
What is the funding instrument type?
The funding instrument type is a grant.
Is cost sharing or matching required?
No. The listing states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of award.
What is the maximum award amount listed for this opportunity?
The award ceiling is listed as 200,000, indicating the maximum amount available under the opportunity as presented in the source data.
How should applicants think about the project scope and budget for an R21?
Based on the description, applicants would be expected to propose an appropriately sized exploratory/developmental project with clearly defined aims and a strong justification for why an R21 is the right fit. The description also notes that budget structure and allowable costs typically follow NIH policy for the R21 mechanism.
Which program areas or CFDA numbers are associated with this opportunity?
The opportunity aligns with multiple program areas captured by the listed CFDA numbers, including Human Genome Research (93.172) as well as related research programs in communication disorders, neuroscience, child health and human development, and aging (93.173, 93.853, 93.865, 93.866). This reflects that ELSI questions can cut across many biomedical fields wherever genomic information is used.
Who is eligible to apply?
Eligibility is broad and includes a wide range of domestic and non-domestic entities. The description lists eligible applicants including:
- Federally recognized Native American tribal governments and tribal organizations
- State and local governments (including counties, cities/townships, and special district governments)
- Independent school districts
- Public housing authorities/Indian housing authorities
- Public and private institutions of higher education
- Nonprofits (including 501(c)(3) and certain non-501(c)(3) entities)
- For-profit organizations (including small businesses and other for-profits)
- Alaska Native and Native Hawaiian Serving Institutions
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Faith-based and community-based organizations
- Regional organizations
- U.S. territories or possessions
- Foreign organizations and foreign components of U.S. organizations
Are foreign organizations allowed to apply?
Yes. The description explicitly includes foreign organizations as eligible applicants, as well as foreign components of U.S. organizations.
Is this opportunity still active?
No. The timeline details indicate this posting is historical rather than active. The source data include an original closing date of September 7, 2014, an archive date of August 10, 2014, and other historical posting/record dates.
What key dates are provided in the listing?
The listing provides these dates: posted date July 18, 2011; creation date July 10, 2014 (likely reflecting a system record creation/update); archive date August 10, 2014; and an original closing date of September 7, 2014.
Where were applicants directed for full details about PA 11 251?
The description indicates applicants were directed to the NIH guide page for PA 11 251 for full details.
Who could be contacted for technical help related to access or linking issues?
The description notes that technical assistance was available through the NIH Office of Extramural Research (OER) webmaster contact for access or linking issues.
What kind of impact or outcomes does the FOA seem to value?
The opportunity emphasizes novel, forward-looking ELSI research with meaningful real-world relevance. As described, competitive projects would typically be expected to make a clear case that the question is timely, the approach is innovative, the work is feasible within an exploratory grant structure, and the results would inform ethical practice, legal policy, institutional governance, clinical implementation, or social understanding related to genomics.
What kinds of stakeholders are mentioned as being affected by genomic data practices?
The description mentions impacts on individuals, families, communities, clinicians, researchers, institutions, and policymakers.
Is this opportunity limited to a single biomedical field?
No. The description frames ELSI issues as cross-cutting and connected to multiple program areas, reflecting that genomic information is used across many biomedical contexts and raises ELSI questions in varied settings.
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Previous opportunity: Ethical Legal and Social Implications (ELSI) of Genomic Research Regular Research Program (R01)
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