Opportunity Information: Apply for PA 11 250
Apply for PA 11 250
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Ethical Legal and Social Implications (ELSI) of Genomic Research Regular Research Program (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.395 Cancer Treatment Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jul 10, 2014 and posted on Jul 18, 2011.
- Applicants must submit their applications by Jul 10, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Public housing authorities/Indian housing authorities City or township governments For profit organizations other than small businesses Independent school districts Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) County governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Ethical, Legal and Social Implications (ELSI) of Genomic Research Regular Research Program (R01) grant opportunity (Funding Opportunity Number PA 11-250) is a National Institutes of Health (NIH) discretionary funding announcement that supports full-scale research projects focused on the ethical, legal, and social issues that arise from human genome research. In practical terms, the program is meant to fund rigorous, hypothesis-driven or conceptually grounded studies that examine how genomic science intersects with people, communities, institutions, health systems, and public policy. The emphasis is not on generating new genomic data for its own sake, but on producing evidence, frameworks, and solutions that help the research enterprise and society use genomic knowledge responsibly, fairly, and effectively.
This opportunity uses the R01 mechanism, which is NIH's standard “regular research project†grant designed for substantial, multi-year investigations led by an independent research team. R01 projects under this announcement typically involve well-developed research aims, a strong methodological plan (for example, empirical bioethics, legal and policy analysis, qualitative or mixed-methods social science, survey research, experimental studies of decision-making, or implementation and evaluation research), and a clear connection to real-world problems created or intensified by genomic research and its applications. Projects commonly address topics such as informed consent and participant understanding in genomics studies, privacy and data sharing, identifiability and re-identification risks, return of results and secondary findings, the responsibilities of researchers and institutions, equity in access to genomic technologies, discrimination and stigmatization, governance of biobanks and large datasets, community engagement in research, and the ethical and social consequences of integrating genomics into clinical care and public health.
The announcement sits within NIH’s broad mission areas and is linked to several CFDA program areas, reflecting the cross-cutting nature of genomics and ELSI questions across health and biomedical research. The CFDA numbers listed include 93.172 (Human Genome Research) and multiple others spanning environmental health, cancer treatment research, neurosciences, child health, and aging research, signaling that ELSI studies can be relevant wherever genomics is used. The funding activity category is listed broadly across domains such as education, environment, health, and income security and social services, which fits the reality that ELSI research often reaches beyond medicine into education, law, insurance, employment, and broader social systems.
Eligibility for this FOA is intentionally expansive. It is open to a wide range of U.S.-based and non-U.S.-based applicant organizations, including public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), state, county, city/township, special district governments, public housing authorities/Indian housing authorities, and federally recognized tribal governments as well as other tribal organizations. The eligibility language also explicitly includes many institution types that NIH often highlights to encourage broad participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Foreign organizations are permitted, and foreign components of U.S. organizations are allowed, which is important because many ELSI questions in genomics are global in nature, especially around data sharing, governance, and cross-border research collaborations. The announcement states there is no cost sharing or matching requirement, meaning applicants are not expected to contribute non-federal funds as a condition of the award.
In terms of timing and status, the FOA was posted on July 18, 2011, and later archived in 2014, with an archive date of August 10, 2014. The original closing date is listed as September 7, 2014, with a current closing date shown as July 10, 2014, alongside a creation date of July 10, 2014, which reflects the recordkeeping history in the source data for this opportunity. Because it is archived, it is not an active open solicitation now, but it remains a useful reference point for understanding NIH’s expectations for ELSI-focused R01 projects and for locating successor ELSI funding announcements that continue to support similar research aims under updated FOAs.
For applicants seeking the full official requirements, application instructions, and NIH-specific policy details, the announcement provides a direct link to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/pa-files/PA-11-250.html). The contact information provided points to the NIH Office of Extramural Research (OER) webmaster addresses for technical access issues or linking problems, indicating that programmatic questions would typically be handled through the NIH scientific/research contacts listed in the full FOA text on the NIH page.
Frequently Asked Questions (FAQs)
What is the ELSI of Genomic Research Regular Research Program (R01) opportunity?
It is an NIH discretionary funding announcement (Funding Opportunity Number PA 11-250) for full-scale research projects focused on the Ethical, Legal and Social Implications (ELSI) that arise from human genome research.
What does "ELSI" mean in the context of this program?
ELSI refers to research on the ethical, legal, and social issues created or intensified by genomic science and its applications, including how genomics affects people, communities, institutions, health systems, and public policy.
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH R01 mechanism, NIH's standard regular research project grant for substantial, multi-year investigations led by an independent research team.
What kinds of projects are a good fit for this FOA?
Projects are expected to be rigorous and either hypothesis-driven or conceptually grounded, with well-developed aims and strong methods. The focus is on producing evidence, frameworks, and solutions that help genomic knowledge be used responsibly, fairly, and effectively.
Is this program meant to generate new genomic datasets?
The emphasis is not on generating new genomic data for its own sake. Instead, it supports research that examines and addresses ethical, legal, and social challenges associated with genomic research and its uses.
What methods are commonly used in projects funded under this announcement?
Examples of methods mentioned include empirical bioethics, legal and policy analysis, qualitative or mixed-methods social science, survey research, experimental studies of decision-making, and implementation and evaluation research.
What topic areas does the FOA highlight as examples?
The FOA describes topics such as informed consent and participant understanding in genomics studies, privacy and data sharing, identifiability and re-identification risks, return of results and secondary findings, responsibilities of researchers and institutions, equity in access to genomic technologies, discrimination and stigmatization, governance of biobanks and large datasets, community engagement, and ethical and social consequences of integrating genomics into clinical care and public health.
How does this opportunity relate to NIH mission areas and CFDA programs?
It is linked to multiple CFDA program areas, reflecting that ELSI questions can arise wherever genomics is used. CFDA numbers listed include 93.172 (Human Genome Research) and others spanning areas like environmental health, cancer treatment research, neurosciences, child health, and aging research.
Why are the listed funding activity categories so broad?
The funding activity category is listed across domains such as education, environment, health, and income security and social services, aligning with the cross-cutting reality that ELSI research often extends into education, law, insurance, employment, and broader social systems.
Who is eligible to apply?
Eligibility is intentionally expansive and includes many U.S.-based and non-U.S.-based applicant organizations. Examples include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), state/local/special district governments, public housing authorities/Indian housing authorities, federally recognized tribal governments, and other tribal organizations.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language explicitly includes institution types often highlighted to encourage broad participation, including HBCUs, Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Are foreign organizations allowed to apply?
Yes. Foreign organizations are permitted, and foreign components of U.S. organizations are allowed. This reflects that many ELSI questions in genomics involve international data sharing, governance, and cross-border collaborations.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Is this funding opportunity currently open?
No. The FOA was archived in 2014, so it is not an active open solicitation now. It may still be useful as a reference for NIH expectations and for identifying successor ELSI funding announcements.
When was the FOA posted and when was it archived?
The FOA was posted on July 18, 2011. It was later archived, with an archive date of August 10, 2014.
What dates are listed for closing, and why might they look inconsistent?
The record shows an original closing date of September 7, 2014, and a current closing date shown as July 10, 2014, alongside a creation date of July 10, 2014. The information provided indicates these reflect recordkeeping history in the source data for the opportunity.
Where can applicants find the official FOA text and requirements?
The announcement points to the NIH Grants Guide page at: http://grants.nih.gov/grants/guide/pa-files/PA-11-250.html
Who should be contacted for technical or access issues with the FOA link?
The contact information provided points to NIH Office of Extramural Research (OER) webmaster addresses for technical access issues or linking problems.
Where do programmatic or scientific questions typically get answered?
Based on the information provided, programmatic questions would typically be handled through the NIH scientific/research contacts listed in the full FOA text on the NIH page.
Browse more opportunities from the same category: Education Environment Health Income Security and Social Services
Next opportunity: Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Award (R21)
Previous opportunity: Minerva Research Initiative (MRI)
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