Opportunity Information: Apply for RFA GM 10 009
Apply for RFA GM 10 009
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.859 Biomedical Research and Research Training 93.879 Medical Library Assistance.
- This funding opportunity was created on Sep 17, 2009 and posted on Sep 17, 2009.
- Applicants must submit their applications by Nov 24, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) funding opportunity (Funding Opportunity Number RFA-GM-10-009) is a National Institutes of Health (NIH) discretionary grant competition designed to back research that is unusually bold, high risk, and potentially transformative. The central aim is to support exceptionally innovative projects that tackle novel hypotheses or notoriously difficult scientific problems where a successful outcome would meaningfully accelerate biomedical or biobehavioral knowledge and strongly advance the mission area of at least one participating NIH Institute. A key point in the program design is that it is meant for genuinely new projects rather than ongoing work; it is not intended to fund continuations of projects that are already underway.
This FOA uses the standard NIH Research Project Grant (R01) mechanism, meaning applicants are proposing a full research project rather than a small exploratory study. At the same time, the solicitation is explicit about what it does not want to support: it is not a pilot-project program. In other words, the FOA is not meant for limited-scope studies whose primary purpose is to generate preliminary data to help the principal investigator seek different or larger funding later. The emphasis is on unconventional ideas with a credible path to major impact, rather than incremental progress or early feasibility testing.
Multiple NIH Institutes and Centers participate, and each sets aside funds with an anticipated range of awards, all contingent on available appropriations and on the receipt of enough highly meritorious applications. The participating components and their stated commitments are: NIGMS with about $6 million total supporting an estimated 18 to 22 awards; NCI with about $3 million for 9 to 11 awards; NIA with about $1 million for 2 to 3 awards; NIAAA with about $600,000 for 2 awards; NIDCR with about $800,000 for 2 to 3 awards; NIDA with about $1 million for 3 to 4 awards; NIMH with about $3 million for 8 to 12 awards; NINDS with about $2 million for 6 awards; and NLM with about $985,000 for 3 awards. The award ceiling listed in the record is $250,000.
Eligibility is broad and includes many common NIH applicant categories across academia, nonprofit, government-affiliated higher education, and industry. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education; nonprofit organizations with 501(c)(3) status (other than higher education) as well as nonprofits without 501(c)(3) status (other than higher education); for-profit organizations other than small businesses; small businesses; and additional categories referenced in the FOA. The opportunity also explicitly includes several institution types often called out in federal eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and non-U.S. entities (foreign organizations), indicating that applicants outside the United States may be eligible where NIH policy allows.
Administratively, this opportunity was posted and created on September 17, 2009, with an original and current closing date of November 24, 2009, and an archive date of December 25, 2009. It is categorized under education and health-related funding activity and is associated with multiple CFDA program areas spanning oral health, mental health, alcohol research, multiple cancer research categories (detection and diagnosis, treatment, biology, and control), neuroscience and neurological disorders, biomedical research and training, and medical library assistance. Cost sharing or matching is not required. The full announcement was made available through the NIH grants guide at the link provided in the source record.
Frequently Asked Questions (FAQs)
What is the EUREKA (R01) funding opportunity?
The Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) is an NIH discretionary grant competition intended to support research that is unusually bold, high risk, and potentially transformative. It focuses on exceptionally innovative projects aimed at novel hypotheses or notoriously difficult scientific problems, where success would significantly accelerate biomedical or biobehavioral knowledge and advance the mission area of at least one participating NIH Institute or Center.
What is the Funding Opportunity Number (FOA number) for this program?
The Funding Opportunity Number is RFA-GM-10-009.
What grant mechanism does this opportunity use?
This opportunity uses the standard NIH Research Project Grant (R01) mechanism, meaning applicants propose a full research project rather than a small exploratory study.
What types of projects is EUREKA intended to support?
EUREKA is designed to support genuinely new, exceptionally innovative projects that are unconventional, high risk, and have a credible path to major impact. The focus is on ideas that could be transformative if they succeed, not on incremental advances.
Are ongoing projects or continuations eligible under this FOA?
The program is intended for genuinely new projects and is not meant to fund continuations of projects that are already underway.
Is this a pilot project or preliminary data program?
No. The FOA is explicit that it is not a pilot-project program. It is not intended for limited-scope studies whose primary purpose is to generate preliminary data to pursue different or larger funding later.
What NIH Institutes and Centers participate in this opportunity?
Multiple NIH Institutes and Centers participate, including: NIGMS, NCI, NIA, NIAAA, NIDCR, NIDA, NIMH, NINDS, and NLM.
How much funding is anticipated, and how many awards are expected?
Each participating NIH component set aside funds with an anticipated range of awards (contingent on appropriations and the number of highly meritorious applications received):
- NIGMS: about $6 million total; estimated 18 to 22 awards
- NCI: about $3 million; estimated 9 to 11 awards
- NIA: about $1 million; estimated 2 to 3 awards
- NIAAA: about $600,000; estimated 2 awards
- NIDCR: about $800,000; estimated 2 to 3 awards
- NIDA: about $1 million; estimated 3 to 4 awards
- NIMH: about $3 million; estimated 8 to 12 awards
- NINDS: about $2 million; estimated 6 awards
- NLM: about $985,000; estimated 3 awards
Is funding guaranteed at the amounts listed?
No. The stated funding levels and award counts are contingent on available appropriations and on receiving a sufficient number of highly meritorious applications.
What is the award ceiling for this opportunity?
The award ceiling listed in the record is $250,000.
Who is eligible to apply?
Eligibility is broad and includes many common NIH applicant categories across academia, nonprofit, government-affiliated higher education, and industry. Eligible applicants include:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations with 501(c)(3) status (other than higher education)
- Nonprofit organizations without 501(c)(3) status (other than higher education)
- For-profit organizations other than small businesses
- Small businesses
- Additional categories referenced in the FOA
Are minority-serving institutions explicitly included as eligible applicants?
Yes. The opportunity explicitly includes several institution types commonly referenced in federal eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The opportunity indicates that non-U.S. entities (foreign organizations) may be eligible where NIH policy allows.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
When was this funding opportunity posted?
The opportunity was posted and created on September 17, 2009.
What was the application closing date?
The original and current closing date listed is November 24, 2009.
When was this opportunity archived?
The archive date listed is December 25, 2009.
What is the general funding activity area for this opportunity?
It is categorized under education and health-related funding activity.
What CFDA program areas are associated with this opportunity?
The opportunity is associated with multiple CFDA program areas spanning oral health, mental health, alcohol research, multiple cancer research categories (detection and diagnosis, treatment, biology, and control), neuroscience and neurological disorders, biomedical research and training, and medical library assistance.
Where can applicants find the full announcement?
The full announcement was made available through the NIH grants guide at the link provided in the source record.
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