Opportunity Information: Apply for PAR 06 411
Apply for PAR 06 411
- The National Institutes of Health in the education environment health sector is offering a public funding opportunity titled "Exploratory Innovations in Biomedical Computational Science and Technology (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.394 Cancer Detection and Diagnosis Research 93.396 Cancer Biology Research 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on May 27, 2009 and posted on May 15, 2006.
- Applicants must submit their applications by Sep 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Independent school districts Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The NIH funding opportunity PAR 06 411, titled Exploratory Innovations in Biomedical Computational Science and Technology (R21), supports early-stage, high-risk, high-impact research in biomedical computing, biomedical informatics, and computational biology. The main goal is to accelerate progress in biomedical research by backing new computational approaches and technologies that can open up fresh scientific opportunities, especially in areas where conventional methods are not enough or where preliminary data are limited. This program is framed around the idea that better computational tools and models can dramatically improve how biomedical data are captured, organized, analyzed, shared, and ultimately translated into health insights.
The scope of projects is broad, as long as the work clearly advances computational science and technology for biomedicine. Examples of relevant areas include database design and data infrastructure, user-facing graphical interfaces, innovative querying and retrieval methods, data visualization and interactive manipulation, and approaches for integrating diverse data types through unified analytical pipelines or integrated toolsets. The announcement also explicitly includes computational and mathematical research such as building and validating structural, functional, integrative, or analytical models, along with simulations that help explain biological systems or predict outcomes. In addition, it encourages tools that support electronic collaboration, reflecting NIH interest in platforms that make it easier for distributed teams to share data, methods, and results efficiently.
This FOA uses the NIH R21 exploratory/developmental grant mechanism, which is designed for innovative projects that are still at an exploratory stage. The expectation is that proposed work will be distinctly different from a standard R01-style project. In practical terms, that means the NIH is not looking for long-term, incremental efforts in a well-established research area under this mechanism. Instead, it is looking for bold ideas, early prototypes, new computational paradigms, or untested methods that could have outsized impact if they work, even if there is little or no preliminary data. Applicants whose projects are better suited to more mature, longer-term development pathways are directed to the parallel R01-related announcement (PAR 06 410) focused on innovations in biomedical computing science and technology.
Funding and project limits reflect the exploratory nature of the R21. The maximum project period is two years. Direct costs are capped at 275,000 total over the two-year period, with an additional constraint that no more than 200,000 in direct costs may be requested in any single year. The NIH notes that actual award sizes and the total number of awards will vary depending on the scientific merit, duration, budget needs, and overall quality of the applications received.
Eligibility is intentionally wide to attract strong ideas from many settings. Eligible applicant organizations include for-profit and non-profit entities, public and private institutions such as universities, colleges, hospitals, and laboratories, and government entities at the state and local levels. Federal institutions may also apply, and foreign institutions are explicitly eligible. The FOA also includes faith-based or community-based organizations, as well as Indian/Native American Tribal Governments (both federally recognized and other than federally recognized) and tribally designated organizations. This broad eligibility suggests NIH is prioritizing innovation wherever it arises, including outside traditional academic environments.
For project leadership, any individual with the expertise, resources, and capability to direct the proposed work may serve as the Project Director/Principal Investigator, as long as they work with an eligible institution to submit the application. The NIH explicitly encourages applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities, consistent with its broader goals around strengthening diversity in the biomedical research workforce. Applicants are also allowed to submit more than one application under this FOA, provided that each submission is scientifically distinct rather than overlapping versions of the same project.
Administrative details indicate the FOA was posted May 15, 2006, with multiple receipt dates (with closing dates listed through September 7, 2009 in the provided record) and an archive date of October 8, 2009. The opportunity is associated with NIH and spans several CFDA program areas, including drug abuse and addiction research, technological innovations to improve human health, and multiple cancer research categories. There is no cost sharing or matching requirement. The full announcement and official instructions were provided via the NIH Grants Guide link (PAR 06 411), and NIH Office of Extramural Research contact information is listed for access or technical issues.
FAQs: NIH PAR 06 411 - Exploratory Innovations in Biomedical Computational Science and Technology (R21)
What is PAR 06 411?
PAR 06 411 is an NIH funding opportunity announcement titled "Exploratory Innovations in Biomedical Computational Science and Technology (R21)." It supports exploratory, early-stage research focused on biomedical computing, biomedical informatics, and computational biology.
What is the main goal of this funding opportunity?
The main goal is to accelerate progress in biomedical research by supporting new computational approaches and technologies that can open up new scientific opportunities, particularly where conventional methods are insufficient or where preliminary data are limited.
What kinds of research does this FOA support?
This FOA supports early-stage, high-risk, high-impact work in biomedical computational science and technology. The scope is broad as long as the project clearly advances computational science and technology for biomedicine.
What areas or project topics are considered within scope?
Examples of relevant areas include database design and data infrastructure, graphical user interfaces, innovative querying and retrieval methods, data visualization and interactive manipulation, and methods for integrating diverse data types through unified analytical pipelines or integrated toolsets.
Does the FOA include computational modeling and simulation work?
Yes. The announcement explicitly includes computational and mathematical research such as building and validating structural, functional, integrative, or analytical models, as well as simulations that explain biological systems or help predict outcomes.
Are collaboration tools or platforms within scope?
Yes. The FOA encourages tools that support electronic collaboration, reflecting NIH interest in platforms that help distributed teams share data, methods, and results more efficiently.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R21 exploratory/developmental grant mechanism, which is intended for innovative projects at an exploratory stage.
How is an R21 under this FOA expected to differ from a standard R01-style project?
The NIH expects the proposed work to be distinctly different from a standard R01-style project. This FOA is not intended for long-term, incremental efforts in well-established research areas; it is aimed at bold ideas, early prototypes, new computational paradigms, or untested methods that could have a high impact if successful.
Is preliminary data required to apply?
This FOA emphasizes exploratory work and notes that it is designed for areas where preliminary data may be limited, including projects with little or no preliminary data.
What if a project is more mature and needs longer-term development?
Applicants with projects better suited to more mature, longer-term development pathways are directed to the parallel R01-related announcement, PAR 06 410, which focuses on innovations in biomedical computing science and technology.
What is the maximum project period?
The maximum project period under this R21 FOA is two years.
What are the budget limits for direct costs?
Direct costs are capped at $275,000 total over the two-year period, and no more than $200,000 in direct costs may be requested in any single year.
How does NIH determine the size and number of awards?
NIH indicates that actual award sizes and the total number of awards will vary depending on the scientific merit, duration, budget needs, and overall quality of the applications received.
Is cost sharing or matching required?
No. The opportunity states that there is no cost sharing or matching requirement.
Which organizations are eligible to apply?
Eligibility is broad and includes for-profit and non-profit entities; public and private institutions such as universities, colleges, hospitals, and laboratories; and state and local government entities. Federal institutions may also apply, and foreign institutions are explicitly eligible.
Are faith-based or community-based organizations eligible?
Yes. The FOA includes faith-based or community-based organizations among eligible applicants.
Are Tribal governments and Tribal organizations eligible?
Yes. Eligible applicants include Indian/Native American Tribal Governments (both federally recognized and other than federally recognized) and tribally designated organizations.
Who can serve as the Project Director/Principal Investigator (PD/PI)?
Any individual with the expertise, resources, and capability to direct the proposed work may serve as PD/PI, as long as the application is submitted through an eligible institution.
Does NIH encourage applications from underrepresented groups?
Yes. NIH explicitly encourages applications from individuals from underrepresented racial and ethnic groups and from individuals with disabilities.
Can an applicant submit more than one application under this FOA?
Yes. Applicants may submit more than one application, provided each submission is scientifically distinct and not an overlapping version of the same project.
When was this FOA posted and when did it close?
The FOA was posted on May 15, 2006. The record notes multiple receipt dates with closing dates listed through September 7, 2009, and an archive date of October 8, 2009.
Which agency is associated with this opportunity?
This opportunity is associated with the National Institutes of Health (NIH).
What CFDA program areas are associated with this opportunity?
The opportunity spans several CFDA program areas, including drug abuse and addiction research, technological innovations to improve human health, and multiple cancer research categories.
Where were the official announcement and instructions provided?
The full announcement and official instructions were provided via the NIH Grants Guide link for PAR 06 411.
Where can applicants get help with access or technical issues?
NIH Office of Extramural Research contact information is listed in the opportunity materials for access or technical issues.
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| Innovations in Biomedical Computational Science and Technology Initiative (STTR R41/R42) Apply for PAR 07 161 Funding Number: PAR 07 161 Agency: National Institutes of Health Category: Education Environment Health Funding Amount: Case Dependent |
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