Opportunity Information: Apply for BAA AFOSR 2011 02

  • The Air Force Office of Scientific Research in the science and technology and other research and development sector is offering a public funding opportunity titled "Fiscal Year 2011 Small Molecule Activation" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.800 Air Force Defense Research Sciences Program.
  • This funding opportunity was created on Nov 18, 2010 and posted on Dec 1, 2010.
  • Applicants must submit their applications by Jan 17, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education.
Apply for BAA AFOSR 2011 02

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Opportunity Summary:

The Fiscal Year 2011 Small Molecule Activation opportunity (Funding Opportunity Number BAA AFOSR 2011 02) was a discretionary, grant-based funding competition run by the Air Force Office of Scientific Research (AFOSR) under the Air Force Research Laboratory (AFRL). Its purpose was to strengthen and sustain university research and education in the chemistry of small molecule activation and closely related technologies, with the longer-term goal of transitioning foundational discoveries into capabilities that matter to U.S. Air Force needs. AFOSR made clear that it was seeking unclassified, fundamental research proposals and that submissions should not include proprietary information. Multiple awards were anticipated, but AFOSR reserved the right to fund all, some, or none of the proposals, and it did not reimburse proposal preparation costs. Proposals and supporting materials would not be returned, and the agency planned to manage the announcement electronically rather than distributing paper copies.

Scientifically, the call was motivated by a gap between what nature accomplishes with simple feedstocks and what synthetic chemistry can reliably do with the same basic building blocks. Natural systems routinely convert very stable small molecules into complex materials through highly selective processes, while many industrial approaches still rely on energy-intensive conditions. A central example highlighted in the announcement was dinitrogen (N2) conversion to ammonia via the Haber-Bosch process, which requires high temperatures, high pressures, and heterogeneous catalysis. Despite the historical importance of Haber-Bosch, AFOSR emphasized that selective, mild-condition activation of N2 remains underdeveloped, even though biomimetic and metal-centered mechanistic insights have started to suggest plausible pathways toward room-temperature, low-pressure catalytic approaches. The announcement also pointed to the growing importance of activating other small molecules such as H2, CO, and CO2, including the idea of using CO2 as a chemical feedstock for greener processes and potentially as a carbon source for liquid fuels.

The technical focus of the program was on building mechanistic understanding of catalytic processes that can activate small inorganic compounds and enable synthetically useful reactions among those small molecules and with carbon sources. The scope explicitly covered elements and simple compounds relevant to Air Force interests, including nitrogen, oxygen, hydrogen, sulfur, silicon, boron, aluminum, phosphorus, and carbon, along with their oxides and hydrides. While the solicitation did not limit investigators to a single catalytic paradigm, it strongly preferred catalytic homogeneous processes that generate products under mild reaction conditions, meaning comparatively low temperatures and pressures. The intent was not incremental optimization of known reactions, but frontier-level exploratory work that pushes fundamental boundaries and could transform how small molecules are used as starting materials for synthesis.

From an application standpoint, AFOSR framed the expected relevance in terms of Air Force priorities: chemistry that enables functional compounds, liquid and solid fuels, propellants, and high-energy-density compounds received special emphasis. At the same time, the opportunity stayed rooted in basic research rather than near-term development, aiming to create new synthetic methodologies and catalytic concepts that could eventually support materials and energy-related technologies derived from cheap, abundant, and potentially renewable feedstocks. The announcement also noted that research in areas like nitrogen and sulfur oxides has historically been driven by pollution, exhaust chemistry, and performance questions, whereas targeted exploration of how these kinds of small molecule building blocks can be selectively activated for constructive synthesis has been fragmented; this program was meant to help fill that gap.

In practical grant terms, the funding instrument type was a grant under the Air Force Defense Research Sciences Program (CFDA 12.800). Eligible applicants were U.S. public/state-controlled institutions of higher education and private institutions of higher education, with no cost sharing or matching requirement. The opportunity was posted on December 1, 2010, with an original and current closing date of January 17, 2011, and an archive date of February 16, 2011. Award sizes were substantial for basic research, with a stated floor of $300,000 and a ceiling of $900,000, and AFOSR expected to make more than one award. The announcement encouraged prospective applicants to contact a program manager before submitting, which is often important in AFOSR programs to ensure fit to the research objectives and to align expectations about scope, novelty, and relevance.

Frequently Asked Questions (FAQs)

What is the name of this funding opportunity?

The opportunity is the Fiscal Year 2011 Small Molecule Activation program, Funding Opportunity Number BAA AFOSR 2011 02.

Which agency ran this competition?

The competition was run by the Air Force Office of Scientific Research (AFOSR) under the Air Force Research Laboratory (AFRL).

What type of funding mechanism was used?

The funding instrument type was a discretionary grant.

What is the CFDA number for this program?

The program was under the Air Force Defense Research Sciences Program (CFDA 12.800).

What was the overall purpose of the opportunity?

The stated purpose was to strengthen and sustain university research and education in the chemistry of small molecule activation and closely related technologies, with a longer-term goal of transitioning foundational discoveries into capabilities relevant to U.S. Air Force needs.

Is this opportunity focused on basic research or applied development?

It was focused on unclassified, fundamental research rather than near-term development, while still emphasizing long-term relevance to Air Force needs.

Were proposals required to be unclassified?

Yes. AFOSR stated it was seeking unclassified, fundamental research proposals.

Could proposals include proprietary information?

No. AFOSR specified that submissions should not include proprietary information.

What scientific problem motivated the program?

The announcement highlighted a gap between what natural systems can do with simple, stable feedstocks under selective conditions and what synthetic chemistry can reliably do with those same building blocks, noting that many industrial approaches remain energy-intensive.

Which small-molecule example was emphasized as a central challenge?

The announcement highlighted activation of dinitrogen (N2), including the contrast between natural nitrogen fixation and the industrial Haber-Bosch process for ammonia, which uses high temperatures, high pressures, and heterogeneous catalysis.

Did the opportunity encourage work toward mild-condition N2 activation?

Yes. AFOSR emphasized that selective, mild-condition activation of N2 remained underdeveloped and pointed to mechanistic insights suggesting plausible pathways toward room-temperature, low-pressure catalytic approaches.

What other small molecules were mentioned as important targets?

The announcement pointed to the growing importance of activating other small molecules such as H2, CO, and CO2.

Did the opportunity mention CO2 as a potential feedstock?

Yes. The call discussed using CO2 as a chemical feedstock for greener processes and potentially as a carbon source for liquid fuels.

What was the technical focus of the research scope?

The technical focus was on building mechanistic understanding of catalytic processes that can activate small inorganic compounds and enable synthetically useful reactions among those small molecules and with carbon sources.

Which elements and simple compounds were explicitly within scope?

The scope explicitly covered elements and simple compounds relevant to Air Force interests, including nitrogen, oxygen, hydrogen, sulfur, silicon, boron, aluminum, phosphorus, and carbon, along with their oxides and hydrides.

Was a specific catalytic paradigm required?

No. The solicitation did not limit investigators to a single catalytic paradigm.

What catalytic approaches were preferred?

The program strongly preferred catalytic homogeneous processes that generate products under mild reaction conditions, meaning comparatively low temperatures and pressures.

What did AFOSR mean by "mild reaction conditions" in this announcement?

Based on the announcement language, "mild" referred to comparatively low temperatures and low pressures.

Was the program looking for incremental improvements to known reactions?

No. The intent was not incremental optimization of known reactions, but frontier-level exploratory work that pushes fundamental boundaries and could transform how small molecules are used as starting materials for synthesis.

How did AFOSR describe the Air Force relevance of the research?

AFOSR framed relevance in terms of Air Force priorities such as chemistry enabling functional compounds, liquid and solid fuels, propellants, and high-energy-density compounds, while keeping the work rooted in basic research.

Did the announcement mention any broader context for why this research area matters?

Yes. It noted that areas like nitrogen and sulfur oxides have historically been driven by pollution, exhaust chemistry, and performance questions, and that constructive, selective activation for synthesis has been fragmented; the program aimed to help fill that gap.

Who was eligible to apply?

Eligible applicants were U.S. public/state-controlled institutions of higher education and U.S. private institutions of higher education.

Was cost sharing or matching required?

No. The opportunity stated there was no cost sharing or matching requirement.

What were the key dates for this opportunity?

The opportunity was posted on December 1, 2010. The original and current closing date was January 17, 2011. The archive date was February 16, 2011.

How many awards did AFOSR expect to make?

AFOSR anticipated making multiple awards, while reserving the right to fund all, some, or none of the proposals.

What was the funding range per award?

The stated award floor was $300,000 and the ceiling was $900,000.

Were proposal preparation costs reimbursed?

No. AFOSR stated it did not reimburse proposal preparation costs.

Would proposals and supporting materials be returned?

No. The announcement stated that proposals and supporting materials would not be returned.

How did AFOSR plan to manage the announcement and materials distribution?

The agency planned to manage the announcement electronically rather than distributing paper copies.

Was contacting AFOSR before submitting encouraged?

Yes. The announcement encouraged prospective applicants to contact a program manager before submitting to help ensure fit to the objectives and alignment on scope, novelty, and relevance.

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