Opportunity Information: Apply for PAR 11 042
Apply for PAR 11 042
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "National Institute on Aging Revision Requests for Active Cooperative Agreements (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Feb 25, 2011 and posted on Nov 18, 2010.
- Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Independent school districts Public and State controlled institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), offered this funding opportunity to support revision requests to already-active NIA cooperative agreements (U01) focused on the genetics of Alzheimer's disease. In practical terms, this was not a call for brand-new, stand-alone projects. It was a mechanism for current NIA U01 awardees working in Alzheimer's genetics to request additional funds and/or propose modifications that expand, refine, or accelerate the scope of work under an existing cooperative agreement. Because the funding instrument is a cooperative agreement (U01), NIA would be expected to have substantial involvement in the scientific direction, coordination, and oversight of the supported activities, which typically includes close collaboration with program staff and adherence to agreed-upon milestones, data-sharing practices, and consortium coordination where applicable.
The opportunity fell under the discretionary category and was aligned with the health activity area, specifically aging research (CFDA 93.866). The stated scientific emphasis was the genetics of Alzheimer's disease, implying that eligible revisions would need to be clearly tied to that domain and justified as a logical extension of the parent U01 award. Revision applications in NIH terminology generally cover requests such as adding new aims that complement the original scope, increasing sample size or adding new cohorts, incorporating new analytic approaches or technologies that were not feasible at the time of the original award, strengthening data integration or validation efforts, or addressing emerging scientific opportunities that can significantly improve the value and impact of the ongoing project. Since this is a revision to an active award, applicants would typically need to show that the parent project is progressing well and that the proposed changes are feasible within the project period and consistent with the overall goals of the existing cooperative agreement.
Eligibility was broad in the sense that many organization types could apply, but it was still restricted by the core requirement that the applicant must already hold an active NIA-supported U01 cooperative agreement in the relevant Alzheimer's genetics area. The eligible applicant categories listed included public and private institutions of higher education, nonprofits (including and excluding 501(c)(3) status), small businesses and other for-profit organizations (excluding small businesses in one category but including them in another listing), and multiple levels of government (state, county, city/township, special district). It also explicitly included a range of mission-focused and community-serving entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), and faith-based or community-based organizations, as well as U.S. territories or possessions and eligible federal agencies. There was no cost-sharing or matching requirement, which means applicants were not required to provide non-federal funds as a condition of receiving the award.
Key timing information indicates the announcement was posted on November 18, 2010, with a creation date of February 25, 2011. The current closing date shown was May 7, 2011, with an original closing date of January 7, 2014, and an archive date of June 7, 2011. That combination suggests this announcement had a limited active window for submissions under the particular cycle referenced, after which it was archived; in NIH systems, archiving typically indicates the announcement is no longer active for new applications under that specific listing. Applicants at the time would have been expected to follow NIH submission policies and the specific instructions in the full funding announcement (PAR-11-042), which was linked through the NIH Grants Guide.
For support, NIH provided contact points aimed mainly at resolving access or linking problems with the electronic announcement, directing inquiries to the NIH Office of Extramural Research (OER) Webmaster via the provided email address. For complete requirements, allowable revision types, application instructions, and any program-specific expectations for Alzheimer's genetics cooperative agreements, applicants would have needed to consult the full text of PAR-11-042 on the NIH website.
Frequently Asked Questions (FAQs)
What agency offered this funding opportunity?
This opportunity was offered by the National Institute on Aging (NIA), which is part of the National Institutes of Health (NIH).
What type of funding mechanism was this?
It supported revision requests to already-active NIA cooperative agreements using the U01 mechanism. A U01 is a cooperative agreement, meaning NIA is expected to have substantial involvement in scientific direction, coordination, and oversight.
Is this opportunity for brand-new projects?
No. This was not a call for brand-new, stand-alone projects. It was specifically a mechanism for current, active NIA U01 awardees to request additional funds and/or propose modifications to expand, refine, or accelerate work under an existing cooperative agreement.
What scientific area did this opportunity focus on?
The stated scientific emphasis was the genetics of Alzheimer's disease. Proposed revisions needed to be clearly tied to Alzheimer's genetics and justified as a logical extension of the parent U01 award.
Who was eligible to apply?
Eligibility included many organization types, but with a key restriction: the applicant must already hold an active NIA-supported U01 cooperative agreement in the relevant Alzheimer's genetics area.
What kinds of organizations were listed as eligible (assuming they meet the active U01 requirement)?
The eligible applicant categories listed included public and private institutions of higher education, nonprofits (with and without 501(c)(3) status), small businesses, other for-profit organizations, and multiple levels of government (state, county, city/township, and special district). The listing also included U.S. territories or possessions and eligible federal agencies.
Did the eligibility list include mission-focused or community-serving institutions?
Yes. The listing explicitly included entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), and faith-based or community-based organizations, provided they also met the requirement of holding an active, relevant NIA U01 cooperative agreement.
What is the key eligibility limitation, despite the broad organization list?
The core limitation is that only current awardees with an already-active NIA-supported U01 cooperative agreement in Alzheimer's genetics could submit a revision request under this opportunity.
What does "revision" mean in this context?
In NIH terminology, a revision application generally refers to a request to change or expand an active award. Examples described in the opportunity summary include adding new aims that complement the original scope, increasing sample size or adding new cohorts, incorporating new analytic approaches or technologies not feasible at the time of the original award, strengthening data integration or validation efforts, or addressing emerging scientific opportunities that increase the impact of the ongoing project.
Do revision requests have to stay connected to the original U01 award?
Yes. The revisions needed to be consistent with the overall goals of the existing cooperative agreement and justified as a logical extension of the parent U01.
Does the parent project need to be performing well to justify a revision?
Yes. Because this was a revision to an active award, applicants would typically be expected to show that the parent project was progressing well and that the proposed changes were feasible within the project period.
What does it mean that this is a cooperative agreement (U01)?
It means NIA would be expected to have substantial involvement in scientific direction, coordination, and oversight. This typically includes close collaboration with program staff and adherence to agreed-upon milestones, data-sharing practices, and consortium coordination where applicable.
Was cost-sharing or matching required?
No. The opportunity stated there was no cost-sharing or matching requirement, meaning applicants were not required to provide non-federal funds as a condition of receiving an award.
What was the CFDA number and activity area associated with this opportunity?
The opportunity was aligned with aging research under CFDA 93.866 and was described under the health activity area.
When was the announcement posted?
The announcement was posted on November 18, 2010.
What creation date was listed?
A creation date of February 25, 2011 was shown.
What were the closing and archive dates shown?
The current closing date shown was May 7, 2011. An original closing date of January 7, 2014 was also shown. The archive date shown was June 7, 2011, which suggests the listing was no longer active for new applications under that specific announcement cycle after it was archived.
What is the funding announcement identifier referenced?
The full funding announcement referenced was PAR-11-042, linked through the NIH Grants Guide.
Where were applicants expected to find the full requirements and application instructions?
Applicants were expected to consult the full text of PAR-11-042 on the NIH website for complete requirements, allowable revision types, application instructions, and any program-specific expectations for Alzheimer's genetics cooperative agreements.
What submission policies applied?
Applicants were expected to follow NIH submission policies and the specific instructions contained in the full funding announcement (PAR-11-042).
Who could be contacted for help with access or linking issues?
NIH provided contact points aimed mainly at resolving access or linking problems with the electronic announcement, directing inquiries to the NIH Office of Extramural Research (OER) Webmaster via the provided email address in the listing.
Is this opportunity described as discretionary?
Yes. It was described as falling under the discretionary category.
What kinds of changes might a revision request cover, based on the summary?
Based on the summary, examples include: requesting additional funds; proposing modifications that expand, refine, or accelerate the existing work; adding complementary new aims; increasing sample size; adding new cohorts; incorporating new analytic approaches or technologies; strengthening data integration or validation; and addressing emerging scientific opportunities that improve the value and impact of the ongoing project.
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