Opportunity Information: Apply for PA 07 034
Apply for PA 07 034
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Focal Cognitive Deficits in CNS Disorders (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research 93.866 Aging Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Nov 8, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Independent school districts Private institutions of higher education Native American tribal governments (Federally recognized) City or township governments Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education State governments Public housing authorities/Indian housing authorities.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Focal Cognitive Deficits in CNS Disorders (R03) opportunity, listed as NIH Funding Opportunity Number PA-07-034, is a small-grant program designed to grow the evidence base around specific, targeted cognitive problems that occur in people with central nervous system (CNS) disorders. Rather than focusing only on broad or global cognitive decline, this announcement emphasizes focal or discrete cognitive deficits and asks applicants to study what these deficits look like, how they develop, and what they mean for day-to-day functioning. The overall goal is to strengthen both basic and translational science, and it explicitly includes intervention research aimed at preventing, reducing, or helping individuals manage these specific cognitive problems.
The announcement is issued by the National Institutes of Health, with direct involvement from the National Institute of Nursing Research (NINR) and the National Institute on Aging (NIA). The Office of Behavioral and Social Sciences Research (OBSSR) also participates to encourage attention to behavioral and social dimensions of health and illness, which signals interest in how cognition connects to real-world behaviors, caregiving contexts, adherence, social functioning, and quality-of-life outcomes. Even though OBSSR is a partner in shaping the scientific direction, the funding itself is provided by the participating NIH Institutes and Centers tied to the FOA.
This FOA uses the NIH Small Research Grant (R03) mechanism, which is meant for smaller, tightly scoped projects that can be completed with limited resources and within a shorter timeframe than larger NIH awards. The R03 mechanism is well-suited for early-stage work that can generate preliminary findings, refine approaches, or establish proof-of-concept results that later support larger applications. The announcement highlights several common R03 project types, including pilot and feasibility studies, secondary analysis of existing datasets, small self-contained research projects, development of research methodology, and development of new research technology. In practical terms, applicants might propose validating a focused cognitive assessment, testing a small intervention targeting a particular cognitive process, or analyzing existing cohort or clinical data to clarify how a specific deficit relates to functional outcomes.
Scientifically, the central theme is understanding the types, nature, and functional consequences of focal cognitive deficits in CNS disorders. That framing encourages proposals that do more than simply document deficits; it invites research that clarifies mechanisms, identifies who is most at risk, distinguishes one deficit profile from another, and connects cognitive findings to meaningful outcomes such as independent living, symptom self-management, safety, communication, employment, social participation, and caregiver burden. Because the FOA spans basic and translational work, relevant projects could range from carefully designed behavioral experiments and measurement development through to early intervention testing, as long as the emphasis remains on specific cognitive deficits and their real-world implications.
Administratively, the opportunity is categorized as a discretionary grant within the Health and Education activity areas, and it is associated with CFDA numbers 93.361 (Nursing Research) and 93.866 (Aging Research). There is no cost sharing or matching requirement, which lowers barriers for many applicants. The posting date is November 8, 2006, with multiple receipt dates listed rather than a single deadline, meaning applications were accepted on recurring due dates during the active period of the announcement. The archive date is February 2, 2010, indicating it is no longer active, but the details remain useful for understanding the NIH priorities and structure of similar, more current FOAs.
Eligibility is broad and includes a wide range of organizations such as public and state-controlled institutions of higher education, private higher education institutions, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), independent school districts, and multiple levels of government (state, county, city/township, special district). The FOA also includes Native American tribal governments (federally recognized) and other tribal organizations. Importantly, foreign institutions are eligible to apply, eligible federal agencies may apply, and faith-based or community-based organizations are also eligible, which opens the door to diverse institutional settings and community-linked research designs.
The NIH also notes that this R03 announcement runs in parallel with other announcements of the same scientific scope that use different grant mechanisms, specifically an R01 version (PA-07-033) and an R21 version (PA-07-035). This parallel structure matters because it signals that the same general topic area could be pursued at different scales: the R03 for small, foundational, or feasibility work; the R21 for exploratory or high-risk/high-reward early studies; and the R01 for larger, fully powered projects with a more developed evidence base. Applicants choosing the R03 pathway are typically positioning their work to establish initial results, refine tools, or demonstrate feasibility before moving to a bigger trial or broader mechanistic program.
For reference and full administrative requirements, NIH directs applicants to the full announcement link hosted on the NIH grants site (http://grants.nih.gov/grants/guide/pa-files/PA-07-034.html). For technical issues accessing the announcement, the contact point provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Focal Cognitive Deficits in CNS Disorders (R03) - NIH PA-07-034
What is the NIH PA-07-034 funding opportunity?
NIH Funding Opportunity Number PA-07-034, titled Focal Cognitive Deficits in CNS Disorders (R03), is a small-grant program that supports research focused on specific, targeted cognitive problems experienced by people with central nervous system (CNS) disorders. The emphasis is on discrete (focal) cognitive deficits rather than broad or global cognitive decline.
What is the purpose of this opportunity?
The purpose is to grow the evidence base around focal cognitive deficits by studying what these deficits look like, how they develop over time, and what they mean for everyday functioning. The announcement aims to strengthen both basic and translational science and explicitly includes intervention research intended to prevent, reduce, or help individuals manage these specific cognitive problems.
What does "focal" or "discrete" cognitive deficits mean in this context?
Within this FOA, "focal" (or "discrete") refers to specific cognitive problems that can be defined and studied as targeted deficits, rather than general cognitive impairment. The announcement encourages applicants to identify and characterize particular cognitive processes or domains and link them to functional consequences in real-world settings.
What kinds of outcomes or impacts does the FOA encourage researchers to study?
The FOA encourages research connecting focal cognitive deficits to meaningful day-to-day outcomes, including independent living, symptom self-management, safety, communication, employment, social participation, caregiver burden, adherence behaviors, social functioning, and quality-of-life outcomes.
Does this FOA support intervention research, or only observational studies?
It supports both. In addition to studies that describe and explain focal cognitive deficits, the FOA explicitly includes intervention research aimed at preventing, reducing, or helping individuals manage specific cognitive problems.
Which NIH organizations are involved in this funding opportunity?
The announcement is issued by the National Institutes of Health (NIH), with direct involvement from the National Institute of Nursing Research (NINR) and the National Institute on Aging (NIA). The Office of Behavioral and Social Sciences Research (OBSSR) also participates to encourage attention to behavioral and social dimensions of health and illness.
What is OBSSR's role in this opportunity?
OBSSR participates to encourage applicants to consider behavioral and social dimensions related to cognition and CNS disorders, such as real-world behaviors, caregiving contexts, adherence, social functioning, and quality-of-life outcomes. While OBSSR helps shape scientific direction, funding is provided by the participating NIH Institutes and Centers tied to the FOA.
What grant mechanism does PA-07-034 use?
This FOA uses the NIH Small Research Grant (R03) mechanism. The R03 mechanism is designed for smaller, tightly scoped projects that can be completed with limited resources and within a shorter timeframe than larger NIH awards.
What types of projects are considered a good fit for the R03 mechanism under this FOA?
The announcement highlights R03-suitable project types such as pilot and feasibility studies, secondary analysis of existing datasets, small self-contained research projects, development of research methodology, and development of new research technology. Examples described in practical terms include validating a focused cognitive assessment, testing a small intervention targeting a particular cognitive process, or analyzing existing cohort or clinical data to clarify how a specific deficit relates to functional outcomes.
Is the focus more on basic science, translational science, or both?
Both. The FOA spans basic and translational work, as long as the project maintains a clear emphasis on specific cognitive deficits and their real-world implications.
What is the central scientific theme of the FOA?
The central theme is understanding the types, nature, development, and functional consequences of focal cognitive deficits in CNS disorders. The framing encourages proposals that clarify mechanisms, identify who is most at risk, distinguish one deficit profile from another, and connect cognitive findings to meaningful functional outcomes.
How is this opportunity categorized administratively?
Administratively, it is categorized as a discretionary grant within the Health and Education activity areas.
Which CFDA numbers are associated with this opportunity?
The opportunity is associated with CFDA 93.361 (Nursing Research) and CFDA 93.866 (Aging Research).
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
When was this funding opportunity posted?
The posting date is November 8, 2006.
Did this FOA have a single application deadline?
No. The FOA lists multiple receipt dates rather than a single deadline, meaning applications were accepted on recurring due dates during the active period of the announcement.
Is PA-07-034 still active?
No. The archive date is February 2, 2010, indicating the FOA is no longer active. However, the details can still be useful for understanding NIH priorities and the structure of similar, current FOAs.
Who is eligible to apply?
Eligibility is broad and includes public and state-controlled institutions of higher education, private higher education institutions, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), independent school districts, and multiple levels of government (state, county, city/township, special district). It also includes Native American tribal governments (federally recognized) and other tribal organizations.
Are foreign institutions eligible to apply?
Yes. The FOA states that foreign institutions are eligible to apply.
Can federal agencies apply under this FOA?
Yes. The FOA indicates that eligible federal agencies may apply.
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly notes that faith-based or community-based organizations are eligible, supporting a range of institutional settings and community-linked research designs.
Are there related NIH opportunities on the same topic using different grant mechanisms?
Yes. NIH notes that this R03 announcement runs in parallel with an R01 version (PA-07-033) and an R21 version (PA-07-035), all sharing the same scientific scope but supporting different project scales and stages of evidence development.
How does the R03 relate to the parallel R21 and R01 announcements?
The FOA describes a parallel structure: the R03 supports small, foundational or feasibility work; the R21 supports exploratory or high-risk/high-reward early studies; and the R01 supports larger, fully powered projects with a more developed evidence base. Applicants selecting the R03 pathway are typically aiming to generate initial results, refine tools, or demonstrate feasibility before moving to larger studies.
Where can applicants find the full FOA text?
The full announcement is hosted on the NIH grants site at: http://grants.nih.gov/grants/guide/pa-files/PA-07-034.html
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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| Focal Cognitive Deficits in CNS Disorders (R21) Apply for PA 07 035 Funding Number: PA 07 035 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Discovery for Nervous System Disorders (R21) Apply for PAR 07 049 Funding Number: PAR 07 049 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Molecular genetics of drug addiction and related co morbidities (R01) Apply for PA 07 073 Funding Number: PA 07 073 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis (R01) Apply for PA 07 021 Funding Number: PA 07 021 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Basic Research in the Bladder and Lower Urinary Tract (R01) Apply for PA 07 023 Funding Number: PA 07 023 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mechanisms of Alcohol Associated Cancers (R01) Apply for PA 07 069 Funding Number: PA 07 069 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research on Chronic Insomnia Disorder (R01) Apply for PA 07 047 Funding Number: PA 07 047 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Discovery for Nervous System Disorders (R01) Apply for PAR 07 048 Funding Number: PAR 07 048 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research On The Reduction And Prevention Of Suicidality (R01) Apply for PA 07 079 Funding Number: PA 07 079 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Risk Factors For Psychopathology Using Existing Data Sets (R01) Apply for PA 07 082 Funding Number: PA 07 082 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R01) Apply for PAR 07 086 Funding Number: PAR 07 086 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Infection Of The Central Nervous System (R01) Apply for PA 07 089 Funding Number: PA 07 089 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV/AIDS, Severe Mental Illness And Homelessness (R01) Apply for PA 07 090 Funding Number: PA 07 090 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Prioritizing Molecular Targets for Cancer Prevention with Nutritional Combinations (R01) Apply for PA 07 100 Funding Number: PA 07 100 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research on Rural Mental Health and Drug Abuse Disorders (R01) Apply for PA 07 103 Funding Number: PA 07 103 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Behavioral and Integrative Treatment Development Program (R01) Apply for PA 07 111 Funding Number: PA 07 111 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R01) Apply for PA 07 113 Funding Number: PA 07 113 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R01) Apply for PA 07 132 Funding Number: PA 07 132 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Development Of Frontal Cortex And Limbic System And Their Roles In Drug Abuse Or Mental Health (R01) Apply for PA 07 121 Funding Number: PA 07 121 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Sarcoidosis Research into the Cause of Multi organ Disease and Clinical Strategies for Therapy (R01) Apply for PA 07 136 Funding Number: PA 07 136 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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