FY11 Vision Research Program Hypothesis Development Award | Apply Online

Opportunity Summary:

The FY11 Vision Research Program (VRP) Hypothesis Development Award is a Department of the Army funding opportunity run through the US Army Medical Research and Materiel Command (USAMRMC), created to push forward new research ideas that could prevent, treat, or reverse vision problems affecting service members, especially those tied to combat-related injuries. The broader VRP, launched in FY09 and expanded with additional congressional funding in FY11, focuses on eye damage and visual dysfunction that can come directly from traumatic eye injuries as well as from traumatic brain injury (TBI). It also welcomes work on eye diseases with different biological causes that ultimately converge on the same outcome: degeneration of essential eye structures and partial or complete loss of vision. The practical goal is clear and mission-driven: generate knowledge and technologies that can restore and maintain visual function in ways that support long-term health and sustained combat readiness, while also producing benefits that extend to veteran and civilian patients.

This specific Hypothesis Development Award is aimed at early-stage, high-risk/high-reward research. It is meant for bold, innovative, and largely untested concepts, including new theories, paradigms, methods, or unconventional approaches that address important problems in traumatic vision injury. The award is positioned as a starting point for ideas that are not yet fully proven, where the main deliverable may be a credible scientific rationale for a new hypothesis or an initial proof-of-principle showing that a novel approach is feasible. It is also explicitly designed to give investigators room to pursue unexpected or serendipitous observations that could open up entirely new lines of investigation. While preliminary data can be included if it exists, the program does not require extensive prior results; instead, it emphasizes strong logic, clear reasoning, and a sound scientific basis for why the proposed work should succeed and why it matters.

From an application and review standpoint, the process is staged. Applicants must first submit a preliminary proposal (a pre-proposal), and only those invited based on that initial submission may submit a full proposal. Full proposals are evaluated through a two-level review system: an independent scientific peer review panel assesses scientific merit, and then a programmatic panel makes funding decisions among scientifically qualified submissions, considering program priorities and overall portfolio balance. The opportunity supports basic, translational, and clinical research, but with an emphasis that the outputs should be positioned to eventually translate into real-world benefit for military and related populations.

Administratively, this opportunity was posted August 5, 2011, with a closing date of December 15, 2011 (and an archive date of January 14, 2012). The funding instrument type listed includes grants and cooperative agreements. The program anticipated making about 8 awards, with an estimated total funding pool of $1.7 million and a maximum award amount (ceiling) of $250,000 per project. There was no cost sharing or matching requirement. Eligibility was described as unrestricted, meaning it was broadly open to different types of applicant organizations, subject to any additional limits described in the full announcement. The funding opportunity number is W81XWH-11-VRP-HDA, associated with CFDA 12.420 (Military Medical Research and Development), and the listed grants officer contact was Mary Rico.

Browse more opportunities from the same agency: Dept. of the Army USAMRAA

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Next opportunity: FY11 Vision Research Program Investigator Initiated Research Award

Previous opportunity: Demonstration Projects for Systems Biology of Aging in Saccharomyces cerevisiae (R01)

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