Opportunity Information: Apply for W81XWH 12 MRPRA CSRA
Apply for W81XWH 12 MRPRA CSRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "FY12 Militarily Relevant Peer Reviewed Alzheimers Disease Research Program (MRPRA) Convergence Science Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Nov 3, 2012 and posted on Sep 29, 2012.
- Applicants must submit their applications by Feb 4, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,600,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 7 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The FY12 Militarily Relevant Peer Reviewed Alzheimers Disease Research Program (MRPRA) Convergence Science Research Award (CSRA) is a Department of Defense research funding opportunity run through the U.S. Army Medical Research Acquisitions Activity (USAMRAA), with the application process administered by the Telemedicine and Advanced Technology Research Center (TATRC). It was released as a program announcement to support the Defense Health Program and is aimed at advancing medical research and development that matters to Service members and Veterans, while also producing benefits that can translate to civilian healthcare.
The scientific and public health motivation behind the program is the growing evidence that traumatic brain injury (TBI), including moderate to severe cases and potentially even mild TBI, can raise long-term risk for Alzheimers disease (AD)-like dementia and other persistent neurological and behavioral problems. The announcement highlights outcomes such as memory loss, depression, aggression, and symptoms that overlap with other neurological disorders. Against this backdrop, the MRPRA mission is to build an integrated, coordinated research effort that clarifies the relationship between TBI and AD and reduces the burden of these conditions, particularly in military populations where TBI exposure can be more common.
For FY12 specifically, the program sets out two equally important research objectives. The first objective is to accelerate the development of research tools and clinically relevant outcome measures that enable earlier detection and more accurate diagnosis of neurological changes linked to TBI-associated Alzheimers disease. In practice, this points applicants toward work that can improve how clinicians and researchers identify, track, and characterize neurodegeneration or AD-like changes after brain injury, including tool development and validation that can move the field toward clearer clinical decision-making. The second objective focuses on developing technologies intended to directly benefit people living with neurological impairment symptoms related to TBI or AD. This includes technology development that is meant to preserve or improve quality of life, emphasizing practical impact on day-to-day function rather than purely descriptive research.
The CSRA mechanism is designed around the idea of convergence science, meaning proposals are expected to bring together multidisciplinary teams to tackle these challenges in an integrated way. The intent is not only to fund individual projects, but to generate research resources, tools, and validated approaches that can be used by health science professionals and practitioners aligned with the program mission. While the military community is the priority population for impact, the program also frames its outcomes as serving a broader public purpose by producing knowledge and technologies that can translate to civilian settings.
Administratively, this opportunity was posted on September 29, 2012 (with creation noted as November 3, 2012) and had an application deadline of February 4, 2013, later archived on March 6, 2013. The funding instrument types listed include cooperative agreements and grants, and the activity category is science and technology research and development under CFDA 12.420 (Military Medical Research and Development). The program anticipated making about seven awards, with an estimated total funding amount of $5.6 million and an award ceiling of $500,000 per award; there was no cost sharing or matching requirement. Eligibility was described as unrestricted, meaning the solicitation was open to a wide range of applicant organization types unless otherwise limited in the full text.
The sponsoring agency is the Department of the Army through USAMRAA, which also negotiates resulting awards. A point of contact was provided for electronic access issues (Mary Rico, Grants Officer, MRPRA CSRA Electronic Access Problems), indicating where applicants could seek help obtaining or navigating the full announcement materials.
Frequently Asked Questions (FAQs)
What is the FY12 MRPRA Convergence Science Research Award (CSRA)?
The FY12 Militarily Relevant Peer Reviewed Alzheimers Disease Research Program (MRPRA) Convergence Science Research Award (CSRA) is a Department of Defense research funding opportunity. It is managed through the U.S. Army Medical Research Acquisitions Activity (USAMRAA), with the application process administered by the Telemedicine and Advanced Technology Research Center (TATRC).
Which agency is sponsoring and issuing this funding opportunity?
The sponsoring agency is the Department of the Army through USAMRAA. USAMRAA is also the organization that negotiates resulting awards.
What is the main purpose of this program?
The program aims to advance medical research and development that is relevant to Service members and Veterans, while also producing benefits that can translate to civilian healthcare. A key focus is building an integrated research effort that clarifies the relationship between traumatic brain injury (TBI) and Alzheimers disease (AD) and helps reduce the burden of these conditions in military populations.
Why does the program focus on traumatic brain injury (TBI) and Alzheimers disease (AD)?
The opportunity is motivated by growing evidence that TBI, including moderate to severe cases and potentially even mild TBI, can increase long-term risk for AD-like dementia and other persistent neurological and behavioral problems. The announcement notes outcomes such as memory loss, depression, aggression, and symptoms overlapping with other neurological disorders.
What are the FY12 research objectives?
The FY12 program states two equally important research objectives:
- Objective 1: Accelerate development of research tools and clinically relevant outcome measures that enable earlier detection and more accurate diagnosis of neurological changes linked to TBI-associated Alzheimers disease.
- Objective 2: Develop technologies intended to directly benefit people living with neurological impairment symptoms related to TBI or AD, with an emphasis on preserving or improving quality of life and practical day-to-day impact.
What does the program mean by "convergence science"?
The CSRA mechanism is built around convergence science, meaning proposals are expected to integrate multidisciplinary teams and approaches to address the stated challenges in a coordinated, integrated way, rather than as isolated single-discipline efforts.
What types of deliverables or outcomes is the program trying to generate?
Beyond supporting individual projects, the program intends to generate research resources, tools, and validated approaches that can be used by health science professionals and practitioners aligned with the program mission. The focus includes both improved detection/diagnosis tools and practical technologies that directly help affected individuals.
Who is the priority population for impact?
The priority population is the military community, including Service members and Veterans, especially given the relevance of TBI exposure. The program also emphasizes broader public benefit through knowledge and technologies that can translate to civilian settings.
What funding instrument types are included?
The opportunity lists cooperative agreements and grants as the funding instrument types.
What is the CFDA number and activity category for this opportunity?
The activity category is science and technology research and development under CFDA 12.420, Military Medical Research and Development.
How many awards were anticipated and what was the total funding estimate?
The program anticipated making about seven awards, with an estimated total funding amount of $5.6 million.
What is the maximum award amount (award ceiling)?
The award ceiling was listed as $500,000 per award.
Is cost sharing or matching required?
No. The opportunity states there was no cost sharing or matching requirement.
Who was eligible to apply?
Eligibility was described as unrestricted, meaning the solicitation was open to a wide range of applicant organization types unless otherwise limited in the full text of the announcement.
When was the opportunity posted and what were the key dates?
The opportunity was posted on September 29, 2012 (with creation noted as November 3, 2012). The application deadline was February 4, 2013, and the opportunity was archived on March 6, 2013.
Is this opportunity still open?
No. Based on the provided dates, the application deadline was February 4, 2013 and the opportunity was later archived on March 6, 2013.
Who administered the application process?
While the funding opportunity is run through USAMRAA, the application process was administered by the Telemedicine and Advanced Technology Research Center (TATRC).
Who should applicants contact for electronic access problems?
A point of contact was provided for electronic access issues: Mary Rico, Grants Officer, listed under "MRPRA CSRA Electronic Access Problems."
What kinds of research fit Objective 1 (tools and outcome measures)?
Objective 1 points applicants toward developing and validating research tools and clinically relevant outcome measures that enable earlier detection and more accurate diagnosis of neurological changes linked to TBI-associated AD. This includes work intended to improve how clinicians and researchers identify, track, and characterize neurodegeneration or AD-like changes after brain injury.
What kinds of projects fit Objective 2 (technologies to benefit patients)?
Objective 2 emphasizes technology development intended to directly benefit individuals experiencing neurological impairment symptoms related to TBI or AD. The stated focus is on preserving or improving quality of life, highlighting practical impact on daily functioning rather than purely descriptive research.
How does this opportunity relate to the Defense Health Program?
The funding opportunity was released as a program announcement to support the Defense Health Program, with the stated intent of advancing medical research and development that matters to Service members and Veterans.
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