Opportunity Information: Apply for RFA MH 13 040

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Grand Challenges in Global Mental Health Integrating Mental Health into Chronic Disease Care Provision in Low and Middle Income Countries (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Feb 3, 2012 and posted on Feb 3, 2012.
  • Applicants must submit their applications by Jun 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • Eligible applicants include: County governments Independent school districts Public and State controlled institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Private institutions of higher education For profit organizations other than small businesses State governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply for RFA MH 13 040

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Opportunity Summary:

The National Institutes of Health (NIH) offered this discretionary grant opportunity, titled "Grand Challenges in Global Mental Health: Integrating Mental Health into Chronic Disease Care Provision in Low and Middle Income Countries (R01)" (Funding Opportunity Number RFA-MH-13-040). It was designed to support R01 research projects that build a stronger evidence base for integrated care models in low- and middle-income countries (LMICs), specifically for patients who are living with both mental health conditions and chronic physical illnesses. The central idea is to move beyond treating mental disorders and chronic medical conditions in separate silos, and instead develop practical, context-sensitive approaches that can be delivered through real-world health systems in resource-limited settings.

The focus of the announcement is on generating rigorous evidence for integrated interventions that are both cost-effective and feasible in LMIC contexts. NIH sought projects that would use existing chronic disease care and treatment platforms as the foundation, then incorporate mental health identification and management into those platforms rather than creating entirely new vertical programs. In other words, applicants were expected to leverage services already used for chronic conditions (for example, routine clinics or long-term care programs) and embed mental health care into the workflows, staffing models, and patient pathways that already exist. A key emphasis was on multi-disease care management approaches, meaning research that addresses more than one condition in a coordinated way and tests whether that coordination improves outcomes compared with usual care.

The FOA highlighted the kinds of impact it hoped integrated care models would achieve, including improvements in patient morbidity and functioning, better recognition and diagnosis of mental illness among people already receiving care for chronic medical illnesses, reduced costs or financial burden on the health care system, and stronger care coordination across services and providers. Beyond clinical outcomes, the announcement also stressed implementation practicality. The goal was not only to show that an intervention can work under ideal conditions, but to establish workable methods for multi-disease management that are realistic for LMIC health systems, where workforce shortages, limited specialty services, and constrained budgets often shape what is possible.

In terms of funding structure, this opportunity used the NIH R01 research project grant mechanism, under the health activity category and CFDA number 93.242 (Mental Health Research Grants). The announcement listed an estimated total funding amount of $2,000,000, with an award ceiling of $350,000, and it stated that there was no cost sharing or matching requirement. The opportunity was posted and created on February 3, 2012, with an original and current closing date of June 20, 2012, and an archive date of July 21, 2012, indicating it is no longer open but remains relevant as a model of what NIH has previously supported in this area.

Eligibility was broad and included many types of applicants, such as public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations (other than small businesses), and multiple levels of government entities (state, county, city/township, special districts), as well as public housing authorities/Indian housing authorities and tribal governments and organizations. The eligibility information also explicitly included a wide range of mission-based and identity-serving institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly for a global mental health initiative, non-U.S. entities (foreign institutions) were eligible to apply, non-U.S. components of U.S. organizations were eligible, and foreign components were allowed as defined under the NIH Grants Policy Statement.

Overall, the opportunity was aimed at strengthening the science and practice of integrated mental and physical health care in LMICs by funding research that tests scalable, affordable, and contextually appropriate models. The expectation was that supported projects would help clarify what integrated care should look like in different LMIC settings, how to deliver it through existing chronic disease platforms, and how to measure its benefits for patients and health systems in ways that matter for long-term sustainability and policy uptake.

Frequently Asked Questions (FAQs)

What is the name of this NIH grant opportunity?

The opportunity is titled "Grand Challenges in Global Mental Health: Integrating Mental Health into Chronic Disease Care Provision in Low and Middle Income Countries (R01)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-MH-13-040.

Which agency offered this funding opportunity?

This discretionary grant opportunity was offered by the National Institutes of Health (NIH).

What type of grant mechanism does this opportunity use?

It uses the NIH R01 Research Project Grant mechanism.

What is the core purpose of the opportunity?

The purpose is to support R01 research projects that build a stronger evidence base for integrated care models in low- and middle-income countries (LMICs) for patients living with both mental health conditions and chronic physical illnesses.

What problem is this opportunity trying to address?

It targets the common problem of treating mental disorders and chronic medical conditions in separate silos, and instead promotes practical approaches that integrate mental health identification and management into chronic disease care in resource-limited settings.

What settings or countries are the focus of the research?

The focus is on low- and middle-income countries (LMICs) and real-world health systems operating in resource-limited contexts.

What kinds of patients are central to the research focus?

The central focus is on patients who are living with both mental health conditions and chronic physical illnesses.

What does "integrated care" mean in the context of this FOA?

Integrated care, as described here, means embedding mental health identification and management into existing chronic disease care and treatment platforms rather than creating separate, stand-alone (vertical) mental health programs.

Does the FOA encourage creating new programs or using existing platforms?

It emphasizes using existing chronic disease care and treatment platforms as the foundation and incorporating mental health care into those platforms.

What are examples of "existing chronic disease care platforms" mentioned in the opportunity description?

Examples described include routine clinics or long-term care programs used for chronic conditions, where mental health care can be integrated into existing workflows, staffing models, and patient pathways.

What does the FOA mean by "multi-disease care management approaches"?

It refers to research that addresses more than one condition in a coordinated way and tests whether that coordination improves outcomes compared with usual care.

What outcomes or impacts is NIH hoping integrated models will achieve?

The FOA highlights outcomes such as improved patient morbidity and functioning, better recognition and diagnosis of mental illness among people receiving care for chronic medical illnesses, reduced costs or financial burden on the health care system, and stronger care coordination across services and providers.

Is the FOA focused only on clinical effectiveness?

No. In addition to clinical outcomes, it emphasizes implementation practicality and generating evidence for interventions that are feasible and cost-effective in LMIC contexts.

What does the FOA say about implementation in real-world LMIC health systems?

The stated goal includes establishing workable methods for multi-disease management that are realistic for LMIC health systems, where workforce shortages, limited specialty services, and constrained budgets often shape what is possible.

How much total funding was estimated for this opportunity?

The announcement listed an estimated total funding amount of $2,000,000.

What was the award ceiling?

The award ceiling listed was $350,000.

Is cost sharing or matching required?

No. The opportunity stated there was no cost sharing or matching requirement.

What is the CFDA number and program area?

The CFDA number is 93.242, under the program area "Mental Health Research Grants."

What were the key dates for posting and closing?

The opportunity was posted and created on February 3, 2012. The original and current closing date was June 20, 2012. The archive date was July 21, 2012.

Is this funding opportunity currently open?

No. The archive date (July 21, 2012) indicates the opportunity is no longer open.

Why might this archived FOA still be useful?

Although it is no longer open, it remains relevant as a model of what NIH has previously supported in global mental health and integrated chronic disease care research in LMICs.

Who was eligible to apply?

Eligibility was broad and included public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations (other than small businesses), and multiple levels of government entities (state, county, city/township, special districts), as well as public housing authorities/Indian housing authorities and tribal governments and organizations.

Are mission-based and identity-serving institutions explicitly included?

Yes. The eligibility information explicitly included institutions and organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.

Are regional organizations and U.S. territories mentioned as eligible?

Yes. Regional organizations and U.S. territories or possessions were explicitly included in the eligibility information.

Are federal agencies eligible?

Yes. Eligible federal agencies were included in the eligibility description.

Could non-U.S. (foreign) institutions apply?

Yes. Non-U.S. entities (foreign institutions) were eligible to apply.

Are non-U.S. components of U.S. organizations eligible?

Yes. Non-U.S. components of U.S. organizations were eligible.

Are foreign components allowed under this FOA?

Yes. Foreign components were allowed as defined under the NIH Grants Policy Statement.

What kind of evidence was NIH seeking from funded projects?

The FOA emphasizes generating rigorous evidence for integrated interventions that are cost-effective and feasible, using existing care platforms and producing findings that inform what integrated care should look like across LMIC settings.

What does the FOA suggest about sustainability and policy relevance?

It indicates an expectation that projects would measure benefits for patients and health systems in ways that matter for long-term sustainability and policy uptake.

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