Opportunity Information: Apply for PA 07 027

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Health Disparities in NIDDK Diseases (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jun 23, 2009 and posted on Nov 20, 2006.
  • Applicants must submit their applications by Sep 7, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Small businesses Private institutions of higher education Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Independent school districts Public housing authorities/Indian housing authorities.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:

The Health Disparities in NIDDK Diseases (R01) funding opportunity (PA 07-027) is a National Institutes of Health (NIH) program announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) focused on research that explains, addresses, and ultimately reduces health disparities across conditions that fall within NIDDKs mission. The core goal is to support projects that improve understanding of why certain populations experience worse outcomes, higher disease burden, reduced access to effective care, or different responses to prevention and treatment strategies, and to generate evidence that can be used to mitigate those inequities. The announcement emphasizes high-priority diseases and complications including diabetes, obesity, and nutrition-related disorders; hepatitis C; gallbladder disease; Helicobacter pylori infection; sickle cell disease; kidney diseases; and metabolic, gastrointestinal, hepatic, and renal complications related to HIV infection. In practical terms, the FOA is meant to encourage research that moves beyond documenting disparities and instead digs into causes, mechanisms, and interventions that can reduce unequal outcomes.

The mechanism used is the NIH Research Project Grant (R01), which generally supports well-developed, hypothesis-driven projects with a solid scientific premise and a plan that can be executed over multiple years. This R01 announcement runs alongside a parallel FOA with the same scientific scope that uses the R21 Exploratory/Developmental mechanism (PA 06-183), which is typically aimed at earlier-stage, higher-risk ideas or preliminary studies. Applicants choosing the R01 route are signaling that they have a more mature project, stronger preliminary data, or a more established research plan appropriate for a full research project grant rather than a pilot-style award.

Funding levels and the number of awards are not preset because NIDDK expects the scope, design, timeline, and cost structure to vary widely depending on the disease area and the type of disparity being addressed. As a result, the total dollars awarded and the number of funded projects depend on the volume of applications, their scientific merit, the requested budgets, and the duration of proposed work. The FOA does not require cost sharing or matching, which is typical for NIH research grants and lowers barriers for many applicants, especially community-based or resource-limited organizations.

Eligibility is broad and includes many organization types across the public, private, nonprofit, and educational sectors. Eligible applicants listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses, and also for-profits other than small businesses), and multiple government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. The opportunity also allows applications from Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments), as well as public housing authorities and Indian housing authorities. Notably, foreign institutions are eligible to apply, eligible agencies of the federal government may apply, and faith-based or community-based organizations are explicitly included, which aligns with the health disparities focus where partnerships and community engagement can be central to meaningful impact.

From an administrative standpoint, the opportunity is categorized as discretionary grant funding under a food and nutrition health activity category and is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The opportunity was posted on November 20, 2006, and uses multiple receipt dates rather than a single deadline, meaning applicants could submit for different cycles as described in the full announcement. The record lists a current closing date of September 7, 2009, with an archive date of October 8, 2009, indicating it is an archived opportunity rather than an active one. The full announcement was hosted through the NIH grants guide at the provided link, and the NIH Office of Extramural Research (OER) webmaster contact is listed for access or technical issues with the posting.

Overall, this FOA is designed for investigators and organizations ready to propose rigorous, R01-level research that targets the roots of unequal health outcomes in NIDDK-relevant diseases and tests strategies to reduce those gaps. It supports a wide range of applicants, including community and faith-based groups, and accommodates varied project sizes and durations, with award decisions driven by the quality and feasibility of the science and its potential to meaningfully reduce health disparities.

Frequently Asked Questions (FAQs): Health Disparities in NIDDK Diseases (R01) - PA 07-027

What is the Health Disparities in NIDDK Diseases (R01) funding opportunity?

This is an NIH program announcement (PA 07-027) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that supports research intended to explain, address, and ultimately reduce health disparities in diseases and conditions within NIDDK's mission.

What is the main purpose of this program announcement?

The core goal is to fund research that moves beyond simply documenting disparities and instead investigates their causes, mechanisms, and potential solutions. Projects are expected to improve understanding of why certain populations experience worse outcomes, higher disease burden, reduced access to effective care, or different responses to prevention and treatment strategies, and to generate evidence that can be used to mitigate those inequities.

Which agency and institute are sponsoring this opportunity?

The opportunity is a National Institutes of Health (NIH) program announcement sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What types of health conditions does the announcement prioritize?

The announcement emphasizes high-priority diseases and complications including diabetes, obesity, and nutrition-related disorders; hepatitis C; gallbladder disease; Helicobacter pylori infection; sickle cell disease; kidney diseases; and metabolic, gastrointestinal, hepatic, and renal complications related to HIV infection.

What is meant by "health disparities" in the context of this FOA?

Within the description provided, health disparities refer to unequal health outcomes or experiences across populations, including worse outcomes, higher disease burden, reduced access to effective care, or different responses to prevention and treatment strategies for NIDDK-relevant conditions.

What funding mechanism is used for this opportunity?

This opportunity uses the NIH Research Project Grant (R01) mechanism, which generally supports well-developed, hypothesis-driven projects with a solid scientific premise and a plan that can be executed over multiple years.

Is there a related or parallel funding opportunity with the same scientific focus?

Yes. The description notes a parallel FOA with the same scientific scope that uses the R21 Exploratory/Developmental mechanism (PA 06-183), which is typically aimed at earlier-stage, higher-risk ideas or preliminary studies.

How is an R01 application expected to differ from an R21 in this program area?

Choosing the R01 route indicates the project is more mature, with stronger preliminary data or a more established research plan appropriate for a full research project grant, rather than a pilot-style award.

Does the FOA set a fixed amount of funding per award or a fixed number of awards?

No. Funding levels and the number of awards are not preset. NIDDK expects project scope, design, timelines, and cost structures to vary widely depending on the disease area and the type of disparity being addressed.

What factors influence how many awards are made and how much funding is awarded?

The total dollars awarded and the number of funded projects depend on the volume of applications, their scientific merit, the requested budgets, and the duration of proposed work.

Is cost sharing or matching required?

No. The FOA does not require cost sharing or matching.

What types of organizations are eligible to apply?

Eligibility is broad and includes public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with or without 501(c)(3) status; for-profit organizations (including small businesses and other for-profits); and multiple government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts.

Are tribal governments and tribal organizations eligible?

Yes. The opportunity allows applications from Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments).

Are public housing authorities eligible to apply?

Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.

Are foreign institutions eligible to apply?

Yes. The description explicitly notes that foreign institutions are eligible to apply.

Can federal government agencies apply?

Yes. Eligible agencies of the federal government may apply.

Are faith-based or community-based organizations eligible?

Yes. Faith-based and community-based organizations are explicitly included as eligible applicants.

How is this opportunity categorized administratively?

The opportunity is categorized as discretionary grant funding under a food and nutrition health activity category and is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

What is the CFDA number associated with this opportunity?

The CFDA number provided is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

When was the opportunity posted?

The record indicates it was posted on November 20, 2006.

Does this FOA use a single deadline or multiple receipt dates?

It uses multiple receipt dates rather than a single deadline, meaning applications could be submitted for different cycles as described in the full announcement.

What are the closing and archive dates listed for this announcement?

The record lists a current closing date of September 7, 2009, and an archive date of October 8, 2009.

Is this an active opportunity?

Based on the closing and archive dates provided, it is described as an archived opportunity rather than an active one.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guide at the provided link (as referenced in the description of the opportunity).

Who is listed as a contact for access or technical issues with the posting?

The NIH Office of Extramural Research (OER) webmaster contact is listed for access or technical issues with the posting.

What kind of research does this FOA encourage, in practical terms?

It encourages research that investigates the roots of unequal health outcomes in NIDDK-relevant diseases, including causes and mechanisms of disparities and strategies or interventions that can reduce those gaps, rather than studies that only describe or document disparities.

What kinds of applicants is this FOA designed to support?

It is designed for investigators and organizations ready to propose rigorous, R01-level research targeting the causes of disparities and testing strategies to reduce unequal outcomes. The broad eligibility and explicit inclusion of community-based and faith-based organizations align with the emphasis on meaningful, real-world impact and potential community engagement.

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