Opportunity Information: Apply for PA 12 127

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Mar 19, 2012 and posted on Mar 19, 2012.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal governments (Federally recognized) Special district governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The grant opportunity titled "Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R01)" (Funding Opportunity Number PA 12-127) is a National Institutes of Health (NIH) funding announcement led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports Research Project Grant (R01) applications that focus on practical, real-world research aimed at improving how prevention, treatment, and recovery support services are delivered for substance-related problems involving drugs, alcohol, and tobacco. The central goal is to strengthen the quality, effectiveness, and efficiency of services and systems that people actually interact with, rather than focusing only on basic science or tightly controlled clinical efficacy trials.

The announcement emphasizes health services research and economic research, meaning it is interested in questions tied to how care is organized, financed, implemented, accessed, and maintained over time, and what outcomes those decisions produce. Projects are encouraged to address one or more of five broad topic areas. First, clinical quality improvement, such as developing, testing, or scaling methods that help programs deliver higher-quality, evidence-based care, improve adherence to clinical guidelines, reduce gaps in services, or strengthen continuing care and recovery supports. Second, organization and delivery of services, which can include studying how staffing models, workflows, integration with primary care or mental health services, telehealth delivery, referral networks, or service coordination affects access, engagement, retention, and outcomes. Third, implementation research, focused on the strategies and conditions that help evidence-based practices get adopted and sustained in routine settings, including examining barriers and facilitators, fidelity versus adaptation, and the role of leadership, policy, reimbursement, and workforce training. Fourth, economic and cost studies, including analyses of costs, cost-effectiveness, cost-benefit, budget impact, and broader economic consequences for health systems and society, such as how different service models influence healthcare utilization, criminal justice involvement, employment, or other high-cost outcomes. Fifth, methodological development, which covers improving the research toolkit itself, such as creating or refining measurement instruments, analytic approaches, data linkage strategies, or evaluation designs commonly used in studying prevention, treatment, and recovery services.

This is a discretionary grant using the NIH R01 mechanism, which generally supports investigator-driven projects with a clearly defined research plan and measurable aims. The activity categories listed for the opportunity fall under education and health, and the related CFDA numbers are 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). There is no cost-sharing or matching requirement, so applicants are not expected to contribute non-federal funds as a condition of the award.

Eligibility is broad and includes many types of organizations capable of conducting rigorous research. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education. The announcement also allows applications from nonprofit organizations, including those with 501(c)(3) status and certain nonprofits without 501(c)(3) status (other than institutions of higher education), along with public housing authorities and Indian housing authorities. For-profit organizations are eligible, including small businesses, and the eligibility language also extends to federally recognized tribal governments and other tribal organizations, as well as regional organizations. In addition, the FOA explicitly notes eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based and community-based organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, non-U.S. entities (foreign institutions) may apply, and non-U.S. components of U.S. organizations are also eligible, with foreign components allowed under NIH policy.

From a timeline standpoint, the opportunity was posted and created on March 19, 2012. The original and current closing date listed is May 7, 2015, and the archive date is June 7, 2015, indicating this specific FOA is no longer accepting applications in its original form. Even so, it is still useful as a blueprint for the kinds of health services, implementation, and economic questions NIDA and NIAAA have historically prioritized, and similar NIH program announcements often reappear in updated versions.

The full announcement was hosted through the NIH grants guide at the provided link (http://grants.nih.gov/grants/guide/pa-files/PA-12-127.html). For technical difficulties accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R01)".

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA 12-127.

Which agencies and NIH institutes lead this funding opportunity?

This is a National Institutes of Health (NIH) funding announcement led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What type of grant mechanism does this opportunity use?

It uses the NIH Research Project Grant (R01) mechanism, which generally supports investigator-driven projects with a clearly defined research plan and measurable aims.

What is the main goal of the program announcement?

The central goal is to strengthen the quality, effectiveness, and efficiency of real-world prevention, treatment, and recovery support services for substance-related problems involving drugs, alcohol, and tobacco.

What kinds of research does this FOA prioritize?

The announcement emphasizes health services research and economic research, focusing on how care is organized, financed, implemented, accessed, and sustained over time, and what outcomes result from those decisions in routine practice settings.

Does the FOA focus on basic science or tightly controlled efficacy trials?

No. The emphasis is on practical, real-world research that improves how services and systems function for people who actually use prevention, treatment, and recovery supports, rather than focusing only on basic science or tightly controlled clinical efficacy trials.

What topic areas are encouraged under this announcement?

Projects are encouraged to address one or more of five broad areas:

  • Clinical quality improvement
  • Organization and delivery of services
  • Implementation research
  • Economic and cost studies
  • Methodological development

What does "clinical quality improvement" mean in this context?

It includes developing, testing, or scaling approaches that help programs deliver higher-quality, evidence-based care, improve adherence to clinical guidelines, reduce gaps in services, and strengthen continuing care and recovery supports.

What does "organization and delivery of services" include?

This area can include studying how staffing models, workflows, service integration (for example, with primary care or mental health), telehealth delivery, referral networks, and service coordination affect access, engagement, retention, and outcomes.

What is meant by "implementation research" for this FOA?

Implementation research focuses on strategies and conditions that help evidence-based practices be adopted and sustained in routine settings. It may examine barriers and facilitators, fidelity versus adaptation, and the role of leadership, policy, reimbursement, and workforce training.

What kinds of economic studies are encouraged?

The FOA encourages analyses such as cost, cost-effectiveness, cost-benefit, budget impact, and broader economic consequences for health systems and society, including impacts on healthcare utilization, criminal justice involvement, employment, and other high-cost outcomes.

What does "methodological development" refer to?

Methodological development includes improving the research toolkit used in prevention, treatment, and recovery services research, such as creating or refining measurement instruments, analytic approaches, data linkage strategies, or evaluation designs.

Is cost sharing or matching required?

No. The announcement states there is no cost-sharing or matching requirement, so applicants are not expected to contribute non-federal funds as a condition of the award.

What activity categories are associated with this opportunity?

The activity categories listed are education and health.

What CFDA numbers are related to this opportunity?

The related CFDA numbers are:

  • 93.273 (Alcohol Research Programs)
  • 93.279 (Drug Abuse and Addiction Research Programs)

Who is eligible to apply?

Eligibility is broad and includes many organization types capable of conducting rigorous research, including:

  • State, county, city or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofit organizations (including 501(c)(3) and certain nonprofits without 501(c)(3), other than institutions of higher education)
  • Public housing authorities and Indian housing authorities
  • For-profit organizations (including small businesses)
  • Federally recognized tribal governments and other tribal organizations
  • Regional organizations
  • U.S. territories or possessions
  • Eligible federal agencies

Are faith-based and community-based organizations eligible?

Yes. The FOA explicitly notes eligibility for faith-based and community-based organizations.

Are minority-serving institutions included in the eligibility language?

Yes. The FOA explicitly notes eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Can for-profit organizations apply?

Yes. For-profit organizations are eligible, including small businesses.

Can non-U.S. (foreign) institutions apply?

Yes. The FOA states that non-U.S. entities (foreign institutions) may apply.

Are non-U.S. components of U.S. organizations eligible?

Yes. Non-U.S. components of U.S. organizations are eligible, and foreign components are allowed under NIH policy.

When was this opportunity posted and created?

The opportunity was posted and created on March 19, 2012.

What was the closing date for applications?

The original and current closing date listed is May 7, 2015.

Is this FOA still accepting applications?

No. The archive date is June 7, 2015, which indicates this specific FOA is no longer accepting applications in its original form.

If it is archived, why might it still be useful?

It can still serve as a blueprint for the types of health services, implementation, and economic questions that NIDA and NIAAA have historically prioritized, and similar NIH program announcements may reappear in updated versions.

Where can the full announcement be found?

The full announcement was hosted on the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-12-127.html

Who should be contacted for technical issues accessing or linking to the announcement?

For technical difficulties accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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