Opportunity Information: Apply for PA 08 265
Apply for PA 08 265
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Mar 19, 2012 and posted on Oct 6, 2008.
- Applicants must submit their applications by Mar 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: County governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Special district governments State governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Small businesses City or township governments Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R03) opportunity (Funding Opportunity Number PA 08 265) is a National Institutes of Health (NIH) funding announcement led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It is focused on health services research that can directly improve the quality, effectiveness, and delivery of prevention and treatment services for drug and alcohol misuse. The emphasis is not on basic science or purely clinical efficacy trials in isolation, but on how services are organized, delivered, measured, and improved in real-world settings where patients actually receive care.
The FOA specifically encourages small research projects that address quality and performance in substance use prevention and treatment systems. Priority topic areas include clinical quality improvement (for example, testing strategies that help providers deliver evidence-based screening, counseling, medication-assisted treatment, referral, follow-up, or continuing care more reliably), organizational and managerial quality improvement (such as workflow redesign, supervision models, staffing strategies, training approaches, or leadership practices that improve program performance), systems of care and collaborative research (including coordination across primary care, specialty treatment, mental health, criminal justice, child welfare, schools, or community-based services), and methodological development (meaning the creation or refinement of the analytic methods, measurement tools, and research instruments used to study substance use services). In practice, this can include work like improving fidelity measures, building better implementation metrics, strengthening patient-reported outcome tools, or refining methods for studying service access, retention, disparities, cost, and outcomes using observational or administrative data.
This announcement uses the NIH Small Research Grant (R03) mechanism. The R03 is designed for short-duration, limited-resource studies that are tightly scoped and feasible to complete without the staffing and infrastructure typically needed for larger R01 projects. The FOA highlights the kinds of projects that fit well under an R03: pilot and feasibility studies that generate preliminary data for larger grants, secondary analyses of existing datasets (such as claims, electronic health records, program records, or national surveys), small self-contained projects that answer a focused service delivery question, and development of research methods or technology that improves how health services research is conducted in substance use settings. The announcement also notes it runs in parallel with companion FOAs of the same scientific scope using other mechanisms: an R01 version (PA 08 263) for full-scale research projects and an R21 version (PA 08 264) for exploratory or developmental work.
Funding levels and the number of awards are not fixed in the announcement. Instead, NIH indicates that award size and project duration will vary depending on the proposed work, and that the total dollars and number of awards will depend on the volume of applications received, their scientific merit, their proposed timelines, and their budgets. Importantly, there is no cost sharing or matching requirement, which means applicants are not expected to contribute non-federal funds as a condition of the award.
Eligibility is broad and includes many types of organizations that might be involved in substance use prevention and treatment research or service systems. Eligible applicants include state, county, city, township, and special district governments; federally recognized tribal governments and other tribal organizations; public and state-controlled institutions of higher education as well as private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3), excluding higher education institutions in the nonprofit category as listed); public housing authorities and Indian housing authorities; small businesses; and for-profit organizations other than small businesses. The FOA also explicitly includes additional eligible applicants such as faith-based and community-based organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations), which signals NIH openness to strong health services research proposals wherever relevant expertise and data access exist.
Administratively, this opportunity was posted October 6, 2008, with later system dates showing creation and closing details (original closing date January 15, 2012; current closing date March 20, 2012; archive date April 20, 2012). It is associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). The full announcement was hosted through the NIH grants guide (linked in the listing), and NIH provided contact support through the NIH Office of Extramural Research (OER) web team for technical access issues.
Overall, PA 08 265 is best understood as an NIH mechanism for targeted, practical, and methodologically sound health services research that can quickly produce actionable findings or tools to improve prevention and treatment for substance use disorders. It is especially well suited for teams that have a focused question, access to relevant service settings or existing datasets, and a plan to generate results that can be scaled up or tested in larger studies later.
Frequently Asked Questions (FAQs)
What is the PA-08-265 grant opportunity?
PA-08-265 is an NIH funding announcement titled "Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R03)." It supports health services research intended to directly improve the quality, effectiveness, and delivery of real-world prevention and treatment services for drug and alcohol misuse.
Which NIH institutes lead this funding opportunity?
The announcement is led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What kind of research does this FOA emphasize?
The focus is on health services research in real-world settings, including how services are organized, delivered, measured, and improved where patients actually receive care. The emphasis is not on basic science or purely clinical efficacy trials conducted in isolation from service delivery systems.
What is the grant mechanism used for PA-08-265?
This opportunity uses the NIH Small Research Grant (R03) mechanism, which is designed for short-duration, limited-resource projects that are tightly scoped and feasible without the infrastructure typical of larger awards.
What types of projects are a good fit for an R03 under this FOA?
The FOA highlights several project types that fit well under an R03, including pilot and feasibility studies that produce preliminary data, secondary analyses of existing datasets (for example claims data, electronic health records, program records, or national surveys), small self-contained studies addressing focused service delivery questions, and development or refinement of methods or technology used in substance use health services research.
What priority research topic areas are encouraged?
The FOA encourages small projects addressing quality and performance in substance use prevention and treatment systems. Priority areas include clinical quality improvement, organizational and managerial quality improvement, systems of care and collaborative research, and methodological development.
What counts as clinical quality improvement in the context of this FOA?
Examples described in the FOA include testing strategies that help providers deliver evidence-based screening, counseling, medication-assisted treatment, referral, follow-up, or continuing care more reliably.
What counts as organizational and managerial quality improvement?
Examples include workflow redesign, supervision models, staffing strategies, training approaches, or leadership practices that improve program performance within prevention and treatment settings.
What does "systems of care and collaborative research" mean here?
It includes research on coordination across settings and sectors such as primary care, specialty treatment, mental health, criminal justice, child welfare, schools, and community-based services.
What does the FOA mean by methodological development?
Methodological development includes creating or refining analytic methods, measurement tools, and research instruments used to study substance use services. Examples mentioned include improving fidelity measures, building better implementation metrics, strengthening patient-reported outcome tools, and refining methods to study access, retention, disparities, cost, and outcomes using observational or administrative data.
Is this FOA intended for basic science projects?
No. The FOA emphasizes practical health services research that improves service delivery and performance in real-world prevention and treatment systems, rather than basic science.
Is this FOA intended for purely clinical efficacy trials?
The FOA indicates the emphasis is not on purely clinical efficacy trials in isolation, but on how services are delivered and improved in real-world systems of care.
Are secondary data analyses allowed?
Yes. The FOA explicitly notes secondary analyses of existing datasets as an example of projects that fit the R03 mechanism, including claims, electronic health records, program records, and national survey data.
Does NIH specify a fixed funding amount or number of awards?
No. The announcement states that funding levels, project duration, total dollars, and the number of awards are not fixed and will vary based on factors such as the number of applications received, scientific merit, proposed timelines, and budgets.
Is cost sharing or matching required?
No. The FOA specifies there is no cost sharing or matching requirement, meaning applicants are not expected to provide non-federal funds as a condition of the award.
Who is eligible to apply?
Eligibility is broad. Eligible applicants include various levels of government (state, county, city, township, special district), federally recognized tribal governments and other tribal organizations, public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3), excluding higher education institutions as categorized under nonprofits in the listing), public housing authorities and Indian housing authorities, small businesses, and for-profit organizations other than small businesses.
Are community-based or faith-based organizations eligible?
Yes. The FOA explicitly includes faith-based and community-based organizations among additional eligible applicants.
Are minority-serving institutions specifically included as eligible applicants?
Yes. The FOA explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other listed entities.
Can federal agencies apply?
Yes. The FOA lists eligible federal agencies among additional eligible applicants.
Are U.S. territories or possessions eligible?
Yes. The FOA includes U.S. territories or possessions among eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The FOA explicitly includes non-U.S. entities (foreign organizations) as eligible applicants.
Are there companion funding opportunities with the same scientific scope but different mechanisms?
Yes. The FOA notes companion announcements of the same scientific scope: an R01 version (PA-08-263) for full-scale projects and an R21 version (PA-08-264) for exploratory or developmental work.
When was this opportunity posted and when did it close?
The opportunity was posted on October 6, 2008. The listing references an original closing date of January 15, 2012, a current closing date of March 20, 2012, and an archive date of April 20, 2012.
Which CFDA numbers are associated with this announcement?
The FOA is associated with CFDA 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).
Where was the full announcement hosted?
The full announcement was hosted through the NIH Grants Guide (as referenced by the listing).
Who provides technical support for access issues related to the announcement?
NIH provided contact support through the NIH Office of Extramural Research (OER) web team for technical access issues.
What is the overall purpose of PA-08-265 in practical terms?
PA-08-265 is intended to support targeted, practical, methodologically sound health services research that can produce actionable findings or tools to improve prevention and treatment for substance use disorders, often in a way that can later be scaled up or tested in larger studies.
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