Opportunity Information: Apply for PA 08 264
Apply for PA 08 264
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Mar 19, 2012 and posted on Oct 6, 2008.
- Applicants must submit their applications by Mar 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Independent school districts Private institutions of higher education City or township governments Special district governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Small businesses State governments Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R21), Funding Opportunity Number PA-08-264, is a National Institutes of Health (NIH) discretionary grant competition led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The central aim is to support exploratory and developmental health services research that can measurably improve the quality of real-world prevention and treatment services for substance use problems, including both drug abuse and alcohol abuse. In practice, this means the opportunity is focused less on basic science and more on how care is delivered, managed, improved, measured, and coordinated in clinics, programs, and systems that serve people at risk for, or living with, substance use disorders.
The FOA specifically encourages projects that fall into one or more of four broad areas. First, it supports clinical quality improvement work, such as testing practical strategies to make prevention or treatment more effective, consistent, timely, patient-centered, or evidence-based in frontline settings. Second, it invites organizational and managerial quality improvement research, which could examine how program leadership, staffing models, supervision, workflow, financing, information systems, or organizational culture affect service quality and outcomes. Third, it highlights systems-of-care and collaborative research, reflecting an interest in how multiple organizations and sectors (for example, primary care, specialty addiction treatment, mental health, criminal justice, schools, child welfare, housing, or public health) coordinate services, share responsibility, and create smoother pathways for patients. Fourth, it encourages methodological development for drug and alcohol services research, including the creation or refinement of research methods, analytic approaches, and measurement instruments that make it easier to evaluate service quality, implementation, outcomes, access, retention, or equity in prevention and treatment.
This opportunity uses the NIH Exploratory/Developmental Research Grant Award (R21) mechanism. The R21 is designed for early-stage, innovative, or high-impact ideas that may still be in the proof-of-concept phase, often generating pilot data, testing new models, or refining measures and methods that can later support larger-scale studies. The announcement is part of a coordinated set of NIH opportunities with the same scientific scope, running in parallel with an R01 version (PA-08-263) for more mature, full-scale research projects and an R03 version (PA-08-265) for smaller studies. Applicants choosing among these mechanisms would typically align the mechanism with the maturity of their preliminary evidence, the size of the proposed work, and the resources needed to answer their research questions.
Funding levels are flexible because the FOA anticipates that proposed projects will differ widely in scope, design, and cost structure. The award ceiling listed for this opportunity is $200,000, and the total number of awards and total dollars ultimately committed depend on the volume and quality of applications received, as well as their requested budgets and project periods. There is no cost-sharing or matching requirement, which is typical for many NIH research grants and can reduce barriers for organizations with limited non-federal funds.
Eligibility is broad and includes many types of institutions and organizations capable of conducting health services research. Eligible applicants include public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education), for-profit organizations (including small businesses and other than small businesses), state, county, city, township, and special district governments, independent school districts, public housing authorities/Indian housing authorities, federally recognized tribal governments, and other tribal organizations. The eligibility information also notes additional eligible applicants such as faith-based and community-based organizations, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), U.S. territories or possessions, regional organizations, certain federal agencies, and even non-U.S. entities (foreign organizations). This breadth signals that NIH is open to applications from many settings where prevention and treatment services are actually delivered and evaluated, including community-based and culturally specific service systems.
From an administrative standpoint, the FOA was posted on October 6, 2008, with an archive date of April 20, 2012. The original closing date listed is January 7, 2012, with a current closing date of March 20, 2012, reflecting the final submission window for that cycle. The Catalog of Federal Domestic Assistance (CFDA) numbers associated with the program are 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs), which helps applicants and institutions track the federal funding streams and reporting categories tied to the award.
Overall, PA-08-264 targets practical, improvement-oriented research that can strengthen how prevention and treatment for drug and alcohol problems are delivered in everyday service settings. It encourages projects that can identify what works to improve quality at the clinical, organizational, and system levels, while also supporting the development of better tools and methods for measuring and analyzing service performance and outcomes. The full announcement is available through NIH at http://grants.nih.gov/grants/guide/pa-files/PA-08-264.html, and assistance is available through the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.
Frequently Asked Questions (FAQs)
What is the funding opportunity PA-08-264?
PA-08-264 is an NIH discretionary grant competition titled "Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R21)." It supports exploratory and developmental health services research aimed at improving real-world prevention and treatment services for substance use problems, including both drug abuse and alcohol abuse.
Which NIH institutes lead this opportunity?
This opportunity is led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What is the main goal of this FOA?
The central goal is to fund health services research that can measurably improve the quality of prevention and treatment services in real-world settings. The emphasis is on how care is delivered, managed, improved, measured, and coordinated across programs and systems that serve people at risk for, or living with, substance use disorders.
Is this opportunity focused on basic science or service delivery?
It is focused more on service delivery and improvement (health services research) than on basic science. Projects are expected to address practical questions about improving prevention and treatment in clinics, programs, and systems.
What grant mechanism does PA-08-264 use?
PA-08-264 uses the NIH Exploratory/Developmental Research Grant Award (R21) mechanism, which is designed for early-stage, innovative, or proof-of-concept projects.
What kinds of projects are a good fit for an R21 under this FOA?
The R21 mechanism is intended for exploratory and developmental work, such as generating pilot data, testing new models, or refining measures and methods that could later support larger-scale studies.
What are the four broad research areas encouraged by the FOA?
The FOA encourages projects in one or more of these four areas: (1) clinical quality improvement, (2) organizational and managerial quality improvement, (3) systems-of-care and collaborative research, and (4) methodological development for drug and alcohol services research.
What does "clinical quality improvement" mean in the context of this FOA?
Clinical quality improvement includes testing practical strategies to make prevention or treatment more effective, consistent, timely, patient-centered, or evidence-based in frontline service settings.
What does "organizational and managerial quality improvement" cover?
This area includes research on how program leadership, staffing models, supervision, workflow, financing, information systems, or organizational culture affect service quality and outcomes.
What does "systems-of-care and collaborative research" focus on?
This area focuses on how multiple organizations and sectors coordinate care and create smoother pathways for patients. Examples of sectors mentioned include primary care, specialty addiction treatment, mental health, criminal justice, schools, child welfare, housing, and public health.
What does "methodological development" mean for this opportunity?
Methodological development includes creating or refining research methods, analytic approaches, and measurement instruments that improve the ability to evaluate service quality, implementation, outcomes, access, retention, or equity in prevention and treatment.
How does this R21 opportunity relate to the related R01 and R03 opportunities?
This FOA is part of a coordinated set of NIH opportunities with the same scientific scope, including an R01 version (PA-08-263) for more mature, full-scale projects and an R03 version (PA-08-265) for smaller studies. Applicants are expected to choose the mechanism that matches the maturity of their evidence base, the scale of work proposed, and the resources needed.
What is the maximum award amount listed for PA-08-264?
The award ceiling listed for this opportunity is $200,000. The FOA also notes that funding levels are flexible because projects may differ widely in scope, design, and cost structure.
How many awards will NIH make under this FOA?
The total number of awards and total dollars committed depend on the volume and quality of applications received, as well as the requested budgets and project periods.
Is cost sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education); for-profit organizations (including small businesses and other than small businesses); and various levels of government (state, county, city, township, and special district governments), among others.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments and other tribal organizations are listed as eligible applicants, and the eligibility notes also reference tribally controlled colleges and universities (TCCUs).
Are faith-based and community-based organizations eligible?
Yes. The eligibility information explicitly notes faith-based and community-based organizations as additional eligible applicants.
Are minority-serving institutions eligible?
Yes. The eligibility information notes historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs) as eligible applicants.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among the additional eligible applicants listed in the eligibility information.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The eligibility information notes that non-U.S. entities (foreign organizations) are eligible applicants.
When was the FOA posted and when was it archived?
The FOA was posted on October 6, 2008, and has an archive date of April 20, 2012.
What were the closing dates listed for this opportunity?
The information provided lists an original closing date of January 7, 2012, and a current closing date of March 20, 2012, reflecting the final submission window for that cycle.
What CFDA numbers are associated with this program?
The CFDA numbers listed are 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).
Where can applicants find the full announcement?
The full announcement is available through NIH at http://grants.nih.gov/grants/guide/pa-files/PA-08-264.html.
Where can applicants get technical assistance related to the posting?
Assistance is available through the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.
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