Opportunity Information: Apply for PA 08 001
Apply for PA 08 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "High Throughput Tools for Brain and Behavior (SBIR R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Jan 26, 2009 and posted on Oct 2, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are not eligible to apply.
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Opportunity Summary:
The NIH funding opportunity titled "High Throughput Tools for Brain and Behavior (SBIR R43/R44)" (Funding Opportunity Number PA-08-001) is a discretionary grant program aimed at supporting small businesses that want to build and ultimately commercialize new high-throughput technologies for collecting and analyzing research data related to brain function and behavior. The central idea is to accelerate discovery in basic behavioral science, neuroscience, and neuroAIDS by making it easier, faster, and more scalable to acquire large, complex datasets and to process those datasets into usable scientific insights. The FOA is aligned with the missions of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS), so proposed tools should clearly connect to research needs in those areas, such as measuring behavior at scale, capturing neural activity more efficiently, or improving data pipelines that can handle high-volume, high-dimensional signals.
This solicitation uses the Small Business Innovation Research (SBIR) grant mechanisms, specifically the R43/R44 pathways. Applicants can propose Phase I projects, Phase II projects, or a Fast-Track application that combines Phase I and Phase II in a single submission. Phase I generally supports early feasibility and proof-of-concept work, while Phase II supports more advanced development, validation, and steps toward commercialization. The FOA also notes that it runs in parallel with a companion announcement of identical scientific scope under the Small Business Technology Transfer (STTR) mechanism (PA-08-002; R41/R42), which is relevant for teams that want a formal small business-academic research partnership structure under STTR rather than SBIR.
In terms of funding levels and project periods, the announcement allows relatively substantial budgets for tool development. For SBIR Phase I, applicants may request up to $300,000 in total costs per year for project periods up to 2 years. For SBIR Phase II, applicants may request up to $500,000 in total costs per year for project periods up to 3 years. The number of awards is not fixed; awards depend on the availability of funds and the volume of high-quality applications received. There is no cost-sharing or matching requirement, which is typical for SBIR programs and reduces the burden on small businesses that are still building out R and D capacity.
Eligibility is centered on small business concerns, with the announcement indicating that additional eligibility details may apply (referenced as being explained in an "Additional Information on Eligibility" section in the full announcement). A key limitation is that foreign institutions are not eligible to apply, which means the applicant organization must be a qualifying small business based in the United States and meeting SBIR requirements. The activity category is health, and the listing references CFDA 93.242 (Mental Health Research Grants), reflecting the programmatic connection to NIMH and related NIH research missions.
Administratively, the opportunity was posted on October 2, 2007, and it uses multiple receipt dates rather than a single deadline, so applications are submitted according to NIH standard cycles described in the full announcement. The archive date is October 8, 2010, indicating the historical window for this particular FOA as written, and applicants would typically confirm whether a current version or reissued opportunity exists when planning submission. For official details, the FOA points to the full NIH Grants Guide posting (PA-08-001), and provides NIH Office of Extramural Research contact help for technical issues accessing the announcement.
Frequently Asked Questions (FAQs)
What is the name and funding opportunity number for this NIH program?
The opportunity is titled "High Throughput Tools for Brain and Behavior (SBIR R43/R44)" and the Funding Opportunity Number (FON) is PA-08-001.
What is this grant intended to support?
This discretionary NIH grant program supports small businesses that want to develop and ultimately commercialize new high-throughput technologies for collecting and analyzing research data related to brain function and behavior.
What is the core goal of the funding opportunity?
The central goal is to accelerate discovery in basic behavioral science, neuroscience, and neuroAIDS by enabling easier, faster, and more scalable acquisition of large, complex datasets and improved processing of those datasets into usable scientific insights.
What types of projects are a good fit for this FOA?
Projects that build high-throughput tools aligned with NIMH and NINDS research needs are a fit. Examples described at a high level include tools for measuring behavior at scale, capturing neural activity more efficiently, or improving data pipelines that can handle high-volume, high-dimensional signals.
Which NIH institutes are most closely aligned with this opportunity?
The FOA is aligned with the missions of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS), so proposed tools should clearly connect to research needs in those areas.
What grant mechanisms does this solicitation use?
This solicitation uses the Small Business Innovation Research (SBIR) grant mechanisms, specifically the R43/R44 pathways.
Can applicants submit Phase I, Phase II, or both?
Yes. Applicants can propose an SBIR Phase I project, an SBIR Phase II project, or a Fast-Track application that combines Phase I and Phase II into a single submission.
What is the difference between Phase I and Phase II under this FOA?
Phase I generally supports early feasibility and proof-of-concept work. Phase II supports more advanced development, validation, and steps toward commercialization.
What is a Fast-Track application in the context of this announcement?
A Fast-Track application combines Phase I and Phase II into one application, allowing a small business to propose a pathway from feasibility through more advanced development and commercialization-oriented work in a single submission.
Is there a related STTR version of this opportunity?
Yes. The FOA notes it runs in parallel with a companion announcement of identical scientific scope under the Small Business Technology Transfer (STTR) mechanism: PA-08-002 (R41/R42).
Why might a team choose the STTR companion announcement instead of SBIR?
The STTR mechanism is relevant for teams that want a formal small business-academic research partnership structure under STTR rather than applying under SBIR.
How much funding can be requested for SBIR Phase I?
For SBIR Phase I, applicants may request up to $300,000 in total costs per year, for project periods up to 2 years.
How much funding can be requested for SBIR Phase II?
For SBIR Phase II, applicants may request up to $500,000 in total costs per year, for project periods up to 3 years.
What are the maximum project periods allowed in Phase I and Phase II?
Phase I projects may be proposed for up to 2 years. Phase II projects may be proposed for up to 3 years.
Is the number of awards predetermined?
No. The number of awards is not fixed and depends on the availability of funds and the volume of high-quality applications received.
Is cost sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement, which is typical for SBIR programs.
Who is eligible to apply?
Eligibility is centered on small business concerns, with the announcement indicating that additional eligibility details may apply as described in an "Additional Information on Eligibility" section in the full announcement.
Are foreign institutions eligible to apply?
No. A key limitation stated in the information provided is that foreign institutions are not eligible to apply.
What does the foreign eligibility restriction imply for applicants?
It means the applicant organization must be a qualifying small business based in the United States and meeting SBIR requirements.
What is the activity category for this opportunity?
The activity category is health.
What CFDA number is associated with this program?
The listing references CFDA 93.242 (Mental Health Research Grants).
When was this funding opportunity posted?
The opportunity was posted on October 2, 2007.
Does this FOA have a single deadline?
No. It uses multiple receipt dates rather than a single deadline, meaning applications are submitted according to NIH standard cycles described in the full announcement.
What is the archive date and what does it suggest?
The archive date is October 8, 2010. This indicates the historical window for this particular FOA as written, and applicants would typically confirm whether a current version or reissued opportunity exists when planning submission.
Where can applicants find the official FOA details?
Official details are available in the NIH Grants Guide posting for PA-08-001, as referenced by the FOA.
Who is listed as a resource for technical issues accessing the announcement?
The FOA provides NIH Office of Extramural Research contact help for technical issues accessing the announcement.
Browse more opportunities from the same category: Health
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Applicants who have applied for this opportunity (PA 08 001) also looked into and applied for these:
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