Opportunity Information: Apply for PA 08 002
Apply for PA 08 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "High Throughput Tools for Brain and Behavior (STTR R41/R42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Jan 26, 2009 and posted on Oct 2, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses.
- Foreign institutions are not eligible to apply.
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Opportunity Summary:
The High Throughput Tools for Brain and Behavior opportunity (Funding Opportunity Number PA 08 002) is an NIH Small Business Technology Transfer (STTR) solicitation that supports small businesses working with a research institution partner to create and move toward commercialization new high throughput technologies for studying the brain and behavior. The main goal is to accelerate research by improving how quickly, how consistently, and how broadly scientists can collect and analyze large volumes of data relevant to basic behavioral science, neuroscience, and neuroAIDS. The scientific focus is aligned with the missions of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS), meaning proposed tools should clearly enable or strengthen research that fits within those institutes core priorities.
The FOA is specifically aimed at technology development rather than hypothesis-driven biomedical discovery. Competitive projects would typically center on platforms, instruments, software, pipelines, or integrated systems that increase throughput for data acquisition and/or data analysis. In practical terms, this can include tools that automate or scale behavioral measurement, enhance neural recording or imaging throughput, enable rapid processing and interpretation of large datasets, or otherwise remove bottlenecks that slow down experiments in brain and behavior research. A key expectation is that the technology being developed has a credible path to real-world use, including dissemination and commercialization, not just a proof-of-concept for academic use.
Applications are accepted under the STTR mechanisms R41 (Phase I) and R42 (Phase II), and the announcement also allows Fast Track submissions that combine Phase I and Phase II into a single application to speed transition when appropriate. This STTR announcement runs in parallel with an SBIR counterpart (PA 08 001) that has the same scientific scope but uses the SBIR mechanisms (R43/R44). Applicants choose the program (STTR vs SBIR) that best fits their team structure and collaboration plan; STTR is designed for projects that formally integrate a small business with a nonprofit research institution through a required partnership.
Funding levels are set to support early-stage feasibility work and then follow-on development. For Phase I, applicants may request up to $300,000 in total costs per year for up to 2 years, which is intended to establish technical feasibility and a strong foundation for further development. For Phase II, applicants may request up to $500,000 in total costs per year for up to 3 years, typically supporting full prototype development, validation, scale-up, robustness testing, user readiness, and other steps needed to move the technology toward adoption and commercialization. As with most NIH funding announcements, awards depend on the availability of funds and the submission of sufficiently strong, meritorious applications, so there is no guaranteed number of awards.
Eligibility is limited to small business concerns, with additional eligibility details provided in the full announcement. Foreign institutions are not eligible to apply under this FOA, which effectively means the applicant small business must meet the applicable US eligibility requirements and the work must be structured within NIH rules for STTR. There is no cost sharing or matching requirement listed for this opportunity. The program falls under the NIH health funding activity category and is associated with CFDA 93.242 (Mental Health Research Grants), reflecting the involvement of NIMH and the broader mental health and neuroscience relevance.
Administratively, the opportunity was posted on October 2, 2007, with multiple receipt dates (recurring submission deadlines) referenced in the full announcement. It is a discretionary grant program operated by the National Institutes of Health. The full text of the announcement was available through the NIH grants guide (historically at http://grants.nih.gov/grants/guide/pa-files/PA-08-002.html), and the NIH Office of Extramural Research webmaster contact is provided for access or linking issues.
FAQs: High Throughput Tools for Brain and Behavior (NIH STTR) - PA-08-002
What is the "High Throughput Tools for Brain and Behavior" funding opportunity?
This opportunity (Funding Opportunity Number PA-08-002) is an NIH Small Business Technology Transfer (STTR) solicitation that supports small businesses, working with a required nonprofit research institution partner, to develop new high throughput technologies for studying the brain and behavior and move them toward commercialization.
What is the main purpose of this FOA?
The main goal is to accelerate brain and behavior research by improving how quickly, consistently, and broadly scientists can collect and analyze large volumes of data relevant to basic behavioral science, neuroscience, and neuroAIDS.
Which NIH institutes are aligned with this opportunity?
The scientific focus is aligned with the missions of the National Institute of Mental Health (NIMH) and the National Institute of Neurological Disorders and Stroke (NINDS). Proposed tools are expected to clearly enable or strengthen research that fits within those institutes' core priorities.
Is this FOA meant for hypothesis-driven biomedical discovery?
No. This FOA is specifically aimed at technology development rather than hypothesis-driven biomedical discovery. Competitive applications typically center on creating or advancing tools and systems that increase throughput for data acquisition and/or data analysis.
What types of projects are considered a strong fit?
Projects that develop platforms, instruments, software, pipelines, or integrated systems that remove bottlenecks in brain and behavior research by increasing throughput. Examples described by the FOA include tools that automate or scale behavioral measurement, enhance neural recording or imaging throughput, or enable rapid processing and interpretation of large datasets.
Does the technology need a commercialization plan?
Yes. A key expectation is a credible path to real-world use, including dissemination and commercialization, not only an academic proof-of-concept.
What grant mechanisms are used under this STTR opportunity?
Applications are accepted under the STTR mechanisms R41 (Phase I) and R42 (Phase II).
Is a Fast Track option available?
Yes. The announcement allows Fast Track submissions that combine Phase I and Phase II into a single application to speed the transition when appropriate.
Is there a related SBIR opportunity?
Yes. This STTR announcement (PA-08-002) runs in parallel with an SBIR counterpart (PA-08-001) with the same scientific scope, but using SBIR mechanisms (R43/R44). Applicants choose STTR vs. SBIR based on their team structure and collaboration plan.
What makes STTR different in this FOA context?
STTR is designed for projects that formally integrate a small business with a nonprofit research institution through a required partnership. This FOA specifically supports that small business + research institution collaboration model.
How much funding is available for Phase I?
For Phase I (R41), applicants may request up to $300,000 in total costs per year for up to 2 years to establish technical feasibility and build a foundation for further development.
How much funding is available for Phase II?
For Phase II (R42), applicants may request up to $500,000 in total costs per year for up to 3 years to support activities such as full prototype development, validation, scale-up, robustness testing, and steps needed to move the technology toward adoption and commercialization.
Is there a guaranteed number of awards?
No. Awards depend on the availability of funds and the submission of sufficiently strong, meritorious applications. The FOA does not guarantee a specific number of awards.
Who is eligible to apply?
Eligibility is limited to small business concerns, with additional eligibility details provided in the full announcement. The FOA is structured under NIH STTR rules, including the required partnership with a nonprofit research institution.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this FOA, meaning the applicant small business must meet applicable U.S. eligibility requirements and structure the work within NIH STTR rules.
Is cost sharing or matching required?
No cost sharing or matching requirement is listed for this opportunity.
What research areas does this FOA emphasize?
The emphasis is on high throughput tools relevant to basic behavioral science, neuroscience, and neuroAIDS, particularly where improved data collection and/or analysis throughput would accelerate research.
What is the assistance listing / CFDA number associated with this opportunity?
The opportunity is associated with CFDA 93.242 (Mental Health Research Grants), reflecting NIMH involvement and broader mental health and neuroscience relevance.
What type of grant program is this?
It is a discretionary grant program operated by the National Institutes of Health (NIH) under the NIH health funding activity category.
When was the opportunity posted, and are there multiple deadlines?
The opportunity was posted on October 2, 2007. The announcement references multiple receipt dates (recurring submission deadlines) in the full announcement.
Where can the full FOA text be found?
The full text was available through the NIH Grants Guide (historically at http://grants.nih.gov/grants/guide/pa-files/PA-08-002.html).
Who is listed for help with access or linking issues?
The NIH Office of Extramural Research webmaster contact is provided in the announcement for access or linking issues.
Browse more opportunities from the same category: Health
Next opportunity: Competing Renewal Awards of SBIR Phase II Grants for Brain and Behavior Tools (R44)
Previous opportunity: High Throughput Tools for Brain and Behavior (SBIR R43/R44)
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