Opportunity Information: Apply for RFA DA 14 010

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "HIV/AIDS and Substance Use among Black/African American Women and Young MSM (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Jun 10, 2013 and posted on Jun 10, 2013.
  • Applicants must submit their applications by Nov 15, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: Native American tribal governments (Federally recognized) Private institutions of higher education Public and State controlled institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) County governments For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Special district governments City or township governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The funding opportunity RFA-DA-14-010, titled "HIV/AIDS and Substance Use among Black/African American Women and Young MSM (R01)," is a National Institutes of Health (NIH) research grant announcement aimed at strengthening the evidence base on how substance use and HIV intersect in populations and contexts that have been comparatively understudied. The core purpose is to generate clearer, more actionable knowledge about the overlapping drivers of HIV risk, HIV transmission, prevention engagement, treatment outcomes, and related health disparities when drug and alcohol use are part of the picture. By focusing on Black/African American women and young men who have sex with men (MSM), the FOA targets groups that carry disproportionate HIV burdens and often face compounded structural and social barriers to prevention and care, including stigma, limited access to culturally responsive services, and higher exposure to socioeconomic instability and criminal legal system involvement.

This announcement sits within a broader, coordinated 2014 expansion of NIH efforts to study HIV/AIDS in the context of drug and alcohol misuse. NIH framed this expansion as "multi-pronged," meaning this R01 is one piece of a larger set of complementary initiatives intended to accelerate progress across several high-need populations and service settings. Related FOAs in that set included research on HIV and substance use among people experiencing homelessness or unstable housing (RFA-DA-14-009), work on integrating substance use services with HIV prevention and treatment inside HIV service delivery environments (RFA-DA-14-011), exploratory studies on the overlap of HIV, chronic pain, and substance use among older adults (RFA-DA-14-012), and a data harmonization coordinating center supporting Seek, Test, Treat, and Retain efforts (RFA-DA-14-007). In practical terms, this signals that NIH was not only interested in individual-level behavior or clinical outcomes in isolation, but also in how environments, systems of care, and service integration shape HIV and substance use outcomes across different groups.

The mechanism for this opportunity is the R01, NIH's standard research project grant, which generally supports well-developed, hypothesis-driven research programs. While the provided synopsis does not list specific scientific aims or required study designs, the emphasis is clearly on building prevention and treatment knowledge that can translate into effective interventions. That can include work that clarifies causal pathways between substance use and HIV vulnerability, identifies leverage points for prevention, tests interventions, or improves linkage and retention in HIV care when substance use complicates service engagement. The phrase "understudied settings that show promise" also points to interest in contexts where innovative prevention and treatment strategies could be implemented or scaled, such as community-based organizations, specialized clinics, or other nontraditional venues that reach populations not well-served by conventional healthcare systems.

Administratively, this is a discretionary grant opportunity in the health and education activity category, tied to CFDA 93.279 (Drug Abuse and Addiction Research Programs). The announcement was posted and created on June 10, 2013, with an original and current closing date of November 15, 2013, and an archive date of December 16, 2013. The estimated total funding listed is $4,500,000, and the FOA explicitly states there is no cost sharing or matching requirement, which reduces barriers for applicants that may not have substantial non-federal resources to contribute.

Eligibility is broad and includes a wide range of domestic U.S. entities across government, education, nonprofit, and private sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), for-profit organizations other than small businesses, small businesses, independent school districts, city/township, county, state, special district governments, public housing authorities/Indian housing authorities, and Native American tribal governments and tribal organizations (including those other than federally recognized). The eligibility section also highlights specific institution types and community-connected entities that NIH often seeks to encourage in disparity-focused research, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based and community-based organizations and eligible federal agencies. At the same time, the FOA restricts foreign involvement: non-U.S. (foreign) institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not permitted, underscoring that the funded work is expected to be conducted within U.S. institutional and geographic contexts.

The announcement is administered by NIH, with the full text historically available via the NIH Grants Guide. For access issues, NIH provided technical contact points through the NIH Office of Extramural Research (OER) webmaster emails for assistance with the electronic announcement or linking problems. Overall, this FOA represents an NIH investment in research that directly addresses HIV disparities by examining, in a targeted way, how substance use and HIV epidemics overlap for Black/African American women and young MSM, and by supporting studies that can inform more effective, culturally and structurally responsive prevention and treatment approaches in real-world settings.

Frequently Asked Questions (FAQs)

What is the funding opportunity number and title?

The funding opportunity is RFA-DA-14-010, titled "HIV/AIDS and Substance Use among Black/African American Women and Young MSM (R01)."

Which federal agency is offering this grant?

This opportunity is administered by the National Institutes of Health (NIH).

What type of grant mechanism is used for this opportunity?

The mechanism is an R01, NIH's standard research project grant mechanism that generally supports well-developed, hypothesis-driven research programs.

What is the main goal of this funding opportunity?

The core purpose is to strengthen the evidence base on how substance use (drug and alcohol use) and HIV intersect in populations and contexts that have been comparatively understudied, with an emphasis on producing clearer, more actionable knowledge that can inform prevention and treatment approaches.

Which populations are the focus of this FOA?

The FOA specifically targets research focused on Black/African American women and young men who have sex with men (MSM), groups described as carrying disproportionate HIV burdens and often facing compounded structural and social barriers to prevention and care.

What topics or outcomes is NIH looking to understand through this research?

Based on the description provided, NIH is interested in research that clarifies how substance use relates to HIV risk, HIV transmission, prevention engagement, treatment outcomes, and related health disparities in the target populations.

Does the opportunity emphasize prevention, treatment, or both?

Both. The description highlights generating knowledge that can translate into effective interventions across prevention and treatment, including linkage and retention in HIV care when substance use complicates engagement.

Are specific study designs or scientific aims required?

The provided synopsis does not list specific required scientific aims or study designs. It emphasizes building actionable knowledge and supporting work that can translate into effective interventions.

What kinds of research activities does the FOA appear to encourage?

The description suggests interest in work that clarifies causal pathways between substance use and HIV vulnerability, identifies leverage points for prevention, tests interventions, and/or improves linkage and retention in HIV care in the presence of substance use.

Does the FOA mention particular settings for research?

Yes. It references "understudied settings that show promise," which points to interest in contexts where innovative prevention and treatment strategies could be implemented or scaled, such as community-based organizations, specialized clinics, or other nontraditional venues that reach populations not well-served by conventional healthcare systems.

How does this FOA fit into NIH's broader efforts?

This R01 is described as part of a coordinated 2014, "multi-pronged" NIH expansion to study HIV/AIDS in the context of drug and alcohol misuse, alongside related initiatives targeting other high-need populations and service settings.

What related funding opportunities were mentioned as part of the broader initiative?

Related FOAs mentioned include: research on HIV and substance use among people experiencing homelessness or unstable housing (RFA-DA-14-009); integration of substance use services with HIV prevention and treatment inside HIV service delivery environments (RFA-DA-14-011); exploratory studies on HIV, chronic pain, and substance use among older adults (RFA-DA-14-012); and a data harmonization coordinating center supporting Seek, Test, Treat, and Retain efforts (RFA-DA-14-007).

What is the CFDA number associated with this opportunity?

The opportunity is tied to CFDA 93.279 (Drug Abuse and Addiction Research Programs).

What is the estimated total funding amount?

The estimated total funding listed is $4,500,000.

Is cost sharing or matching required?

No. The FOA explicitly states there is no cost sharing or matching requirement.

When was the announcement posted/created?

The announcement was posted and created on June 10, 2013.

What were the closing date and archive date?

The original and current closing date is November 15, 2013, and the archive date is December 16, 2013.

Who is eligible to apply?

Eligibility is broad and includes many domestic U.S. entities across government, education, nonprofit, and private sectors, including public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status, other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and multiple units of local and state government.

Which government entities are listed as eligible applicants?

Eligible government-related applicants include independent school districts; city/township governments; county governments; state governments; special district governments; public housing authorities/Indian housing authorities; Native American tribal governments; and Native American tribal organizations (including those other than federally recognized).

Are community-based and faith-based organizations eligible?

Yes. The eligibility section explicitly mentions faith-based and community-based organizations as eligible.

Are minority-serving institutions specifically encouraged or listed?

Yes. The eligibility information highlights institution types often encouraged in disparity-focused research, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Are for-profit organizations eligible?

Yes. The FOA lists for-profit organizations other than small businesses as eligible, and it also separately lists small businesses as eligible.

Are foreign (non-U.S.) institutions eligible to apply?

No. Non-U.S. (foreign) institutions are not eligible to apply.

Can a U.S. organization apply if the project includes a non-U.S. component?

No. Non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not permitted.

Where was the full text of the announcement historically made available?

The full text was historically available via the NIH Grants Guide.

Who should be contacted for technical issues accessing the announcement?

NIH provided technical contact points through the NIH Office of Extramural Research (OER) webmaster emails for assistance with electronic announcement access or linking problems.

What broader barriers or disparities does the FOA context highlight for the target populations?

The description notes compounded structural and social barriers including stigma, limited access to culturally responsive services, higher exposure to socioeconomic instability, and involvement with the criminal legal system.

Is the opportunity described as discretionary and, if so, in what activity category?

Yes. It is described as a discretionary grant opportunity in the health and education activity category.

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