Opportunity Information: Apply for RFA DA 12 002
Apply for RFA DA 12 002
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "HIV/AIDS Implementation Science Targeting Drug Using Populations A Collaboration with PEPFAR (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Feb 16, 2011 and posted on Feb 16, 2011.
- Applicants must submit their applications by Aug 1, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education City or township governments County governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The funding opportunity titled "HIV/AIDS Implementation Science Targeting Drug Using Populations: A Collaboration with PEPFAR (R01)" (Funding Opportunity Number RFA-DA-12-002) is a discretionary NIH grant program led by the National Institute on Drug Abuse (NIDA) in collaboration with the Office of the Global AIDS Coordinator. Its purpose is to support implementation science research that can directly inform the Presidents Emergency Plan for AIDS Relief (PEPFAR) as it works to improve how HIV prevention, treatment, and care services are delivered to people who use drugs. The central emphasis is not on basic discovery, but on practical, real-world strategies for making HIV service delivery more efficient, more effective, and more cost-effective in settings where drug use contributes to HIV risk and undermines engagement across the HIV care continuum.
This opportunity uses the R01 research project grant mechanism, meaning applicants are expected to propose a clearly defined, hypothesis-driven or question-driven research plan that can produce actionable evidence for programs operating at scale. The focus on implementation science signals that competitive applications would typically examine how to adopt, integrate, optimize, and sustain evidence-based HIV interventions in real service systems, such as clinics, community programs, outreach platforms, and other public health delivery structures that reach drug-using populations. Projects are intended to generate results that decision-makers can use, including lessons about feasibility, acceptability, fidelity, reach, equity, cost, and measurable effects on prevention and treatment outcomes. In other words, the grant is aimed at closing the gap between what is known to work and what is actually delivered in PEPFAR-relevant contexts, particularly for populations facing stigma, criminalization, unstable housing, co-occurring mental health issues, and other barriers that commonly affect people who use drugs.
The program sits within the broader NIH mission area of drug abuse and addiction research (CFDA 93.279) and aligns with health and education activity categories, reflecting its dual interest in service delivery systems and the public health impacts of improved implementation. The estimated total funding level listed for the announcement is $4,000,000, and the announcement explicitly notes that there is no cost sharing or matching requirement, which means applicants are not expected to contribute non-federal funds as a condition of the award. The opportunity was posted on February 16, 2011, with an original and current closing date of August 1, 2011, and an archive date of September 1, 2011, indicating that this particular announcement is historical and no longer accepting applications, though it remains useful as a model for similar current NIH/PEPFAR implementation science priorities.
Eligibility is broad and includes a wide range of domestic and non-domestic organizations, reflecting the global nature of PEPFAR and the diversity of organizations involved in HIV programming. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts, as well as public and private institutions of higher education. The eligibility list also includes nonprofit organizations both with and without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), and public housing authorities, including Indian housing authorities. In addition, the announcement highlights specific categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. Federally recognized tribal governments, other tribal entities, U.S. territories or possessions, regional organizations, and even non-U.S. entities (foreign organizations) are also included, which is particularly relevant for implementation studies embedded in international HIV service delivery settings.
From a practical standpoint, the opportunity is designed for applicants who can partner with health systems, community organizations, and program implementers to study implementation challenges and solutions affecting drug-using populations within HIV programs. The implicit deliverable is evidence that helps PEPFAR and its partner countries refine program models so that more people who use drugs can be reached, started on prevention or treatment, retained in care, and supported to achieve better outcomes, while using resources efficiently. The announcement provides an additional information link to the NIH grants guide page for the full details and includes contact guidance through the NIH Office of Extramural Research (OER) webmaster for technical access issues.
Frequently Asked Questions (FAQs)
What is the name and number of this funding opportunity?
The opportunity is titled "HIV/AIDS Implementation Science Targeting Drug Using Populations: A Collaboration with PEPFAR (R01)" and the Funding Opportunity Number is RFA-DA-12-002.
Which agencies are leading this opportunity?
This is a discretionary NIH grant program led by the National Institute on Drug Abuse (NIDA) in collaboration with the Office of the Global AIDS Coordinator, with the intent to generate evidence that can directly inform PEPFAR programs.
What is the main purpose of the grant?
The purpose is to support implementation science research that improves how HIV prevention, treatment, and care services are delivered to people who use drugs, in ways that are relevant to PEPFAR and real-world HIV service systems.
What does "implementation science" mean in this announcement?
In this context, implementation science focuses on practical, real-world strategies to adopt, integrate, optimize, and sustain evidence-based HIV interventions within actual service delivery systems (for example, clinics, community programs, outreach platforms, and other public health delivery structures reaching drug-using populations). The emphasis is on closing the gap between what is known to work and what is delivered in practice.
Is this grant focused on basic discovery research?
No. The central emphasis is not on basic discovery. It is focused on applied, real-world implementation strategies that can make HIV service delivery more efficient, more effective, and more cost-effective for people who use drugs in PEPFAR-relevant settings.
What grant mechanism is used?
The opportunity uses the NIH R01 research project grant mechanism, meaning applicants are expected to propose a clearly defined research plan that is hypothesis-driven or question-driven and can produce actionable evidence for programs operating at scale.
What kinds of outcomes or evidence are projects expected to generate?
Projects are intended to generate results decision-makers can use, including lessons about feasibility, acceptability, fidelity, reach, equity, cost, and measurable effects on prevention and treatment outcomes, especially across the HIV care continuum for people who use drugs.
What populations and barriers are specifically emphasized?
The announcement highlights people who use drugs and the barriers that often affect engagement in HIV prevention and care, including stigma, criminalization, unstable housing, co-occurring mental health issues, and other challenges that can undermine progress across the HIV care continuum.
How does this opportunity connect to PEPFAR?
The intent is to produce implementation evidence that can directly inform PEPFAR as it works to improve delivery of HIV prevention, treatment, and care services for drug-using populations, including program models that can be used at scale.
What is the estimated total funding level listed for the announcement?
The estimated total funding level listed is $4,000,000.
Is cost sharing or matching required?
No. The announcement explicitly states there is no cost sharing or matching requirement, so applicants are not expected to contribute non-federal funds as a condition of the award.
What is the CFDA number and NIH mission area associated with this program?
The program sits within NIH's drug abuse and addiction research mission area and is identified under CFDA 93.279.
When was this opportunity posted, and what were the closing dates?
It was posted on February 16, 2011. The original and current closing date listed is August 1, 2011. The archive date is September 1, 2011.
Is this funding opportunity still accepting applications?
No. The listed closing date (August 1, 2011) and archive date (September 1, 2011) indicate this is a historical announcement and is no longer accepting applications, though it may serve as a model for similar NIH/PEPFAR priorities.
Who is eligible to apply?
Eligibility is broad and includes domestic and non-domestic organizations. Eligible applicants include many government entities, educational institutions, nonprofits, for-profits, tribal entities, U.S. territories, regional organizations, and foreign organizations.
What types of U.S. government entities are eligible?
Eligible government applicants include state, county, city, or township governments; special district governments; and independent school districts.
Are colleges and universities eligible?
Yes. Public and private institutions of higher education are eligible, including specific categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions.
Are nonprofit organizations eligible, including those without 501(c)(3) status?
Yes. Nonprofit organizations are eligible both with and without 501(c)(3) status.
Are for-profit organizations eligible?
Yes. For-profit organizations are eligible, including small businesses and other for-profit entities.
Are public housing authorities eligible?
Yes. Public housing authorities are eligible, including Indian housing authorities.
Are faith-based and community-based organizations eligible?
Yes. The eligibility list includes faith-based or community-based organizations.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments and other tribal entities are included in the eligibility list.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among eligible applicants.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-U.S. entities (foreign organizations) are included, which aligns with the global nature of PEPFAR and the reality that implementation research may be embedded in international HIV service delivery settings.
What types of settings or delivery systems does the announcement envision for the research?
The announcement points to real service systems such as clinics, community programs, outreach platforms, and other public health delivery structures that reach people who use drugs.
What is the practical expectation for applicants beyond the research plan?
The opportunity is designed for applicants who can partner with health systems, community organizations, and program implementers to study implementation challenges and test solutions that can improve HIV prevention and treatment engagement among people who use drugs.
What is the implied deliverable of funded projects?
The implied deliverable is actionable evidence that helps PEPFAR and partner countries refine program models so that more people who use drugs can be reached, started on prevention or treatment, retained in care, and supported to achieve better outcomes while using resources efficiently.
Where can applicants find the full official details for this announcement?
The announcement references an additional information link to the NIH grants guide page for full details.
Who should be contacted for technical access issues related to the announcement information?
For technical access issues, the announcement provides contact guidance through the NIH Office of Extramural Research (OER) webmaster.
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