Opportunity Information: Apply for PAR 11 126
Apply for PAR 11 126
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Silvio O. Conte Centers for Basic and Translational Mental Health Research (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Feb 16, 2011 and posted on Feb 16, 2011.
- Applicants must submit their applications by May 25, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Public housing authorities/Indian housing authorities State governments County governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Silvio O. Conte Centers for Basic and Translational Mental Health Research (P50) funding opportunity is a National Institute of Mental Health (NIMH) center grant designed to support ambitious, highly integrated team science in mental health research. The program is aimed at research groups that can bring together multiple investigators working across different levels of analysis (for example, molecules, cells, circuits, behavior, and clinical phenomena) and combine them in a way that produces a whole that is meaningfully greater than the sum of its parts. NIMH is explicitly looking for integrative, novel, and creative experimental approaches that take on high-risk, high-impact scientific questions that would be difficult to accomplish through more standard, single-project grant mechanisms.
The scientific goals of the Conte Centers program focus on three broad, connected priorities. First, NIMH wants to advance foundational brain and behavior science that improves understanding of mental disorders relevant to mental health, meaning the center should generate fundamental knowledge that can reshape how the field conceptualizes mechanisms of mental illness. Second, the program emphasizes translation and integration between basic neuroscience and clinical research, particularly where that integration can move the field forward on severe mental illnesses by connecting mechanistic discoveries to human symptoms, clinical trajectories, or treatment-relevant targets. Third, the opportunity highlights developmental psychopathology, encouraging research that clarifies neurobehavioral developmental mechanisms and the trajectories that lead to psychopathology beginning in childhood and adolescence, including how early biological and behavioral processes evolve over time into later risk or disorder.
A defining feature of these centers is the expectation of extraordinary synergy and integration. Applicants are expected to propose an interdisciplinary structure where projects and shared resources are coordinated around a central set of questions, and where collaboration is not simply parallel work under one umbrella but rather tightly interdependent research activities that continuously inform one another. In other words, the center should be built so that the combined approach enables discoveries that could not realistically be achieved if the components were funded or executed separately. The emphasis on being beyond what typical mechanisms can support is a key screening concept: Conte Centers are meant for unusually complex or integrative programs with clear justification for why a center-level award is required.
In addition to the research mission, the program is also positioned as a training and workforce-development platform. Conte Centers are expected to create interdisciplinary basic and/or translational research experiences for individuals in training, using the center environment to expose trainees to cross-cutting methods, conceptual frameworks, and collaborative practices that span basic and clinical neuroscience. This reflects NIMH interest in cultivating scientists who can operate fluently across traditional disciplinary boundaries and accelerate progress in mental health research.
Administratively, this opportunity is a discretionary grant funded under the NIH umbrella, with the activity aligned to health research and listed under CFDA 93.242 (Mental Health Research Grants). The funding opportunity number is PAR-11-126, and the posting date was February 16, 2011. The original and current closing date listed is May 25, 2013, with an archive date of June 25, 2013, indicating the announcement is historical rather than currently open under that specific posting. The opportunity does not require cost sharing or matching.
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories as specified), small businesses, and for-profit organizations other than small businesses. Government eligibility spans state, county, and city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility language also explicitly includes a range of mission-driven and community-rooted institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), federally recognized Native American tribal governments and other tribal organizations, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, along with eligible federal agencies.
For applicants seeking the official full announcement details, the opportunity points to the NIH Grants Guide page for PAR-11-126 (http://grants.nih.gov/grants/guide/pa-files/PAR-11-126.html). The listing also provides NIH Office of Extramural Research (OER) webmaster contact information for technical access or linking issues.
Frequently Asked Questions (FAQs)
What is the Silvio O. Conte Centers for Basic and Translational Mental Health Research (P50) opportunity?
This opportunity is an NIMH center grant (P50) designed to support ambitious, highly integrated team science in mental health research. It is meant for interdisciplinary groups that can combine multiple investigators and levels of analysis into a single, tightly connected program.
Which NIH institute offers this program?
The program is offered by the National Institute of Mental Health (NIMH) under the NIH umbrella.
What is the funding opportunity number?
The funding opportunity number is PAR-11-126.
What is the CFDA number associated with this opportunity?
The listing is under CFDA 93.242 (Mental Health Research Grants).
What type of grant mechanism is this?
It is a discretionary grant and uses the P50 center grant activity to support a coordinated, multi-component research center.
What kind of science is NIMH trying to support through these centers?
NIMH is looking for integrative, novel, and creative experimental approaches that address high-risk, high-impact scientific questions in mental health research, especially those that would be difficult to accomplish through standard single-project grant mechanisms.
What does NIMH mean by “highly integrated team science” for a Conte Center?
The expectation is extraordinary synergy and integration across projects and shared resources. Collaboration should be tightly interdependent, with center components continuously informing one another, rather than multiple parallel projects operating under one administrative umbrella.
What are the main scientific priorities of the Conte Centers program?
The goals are organized around three connected priorities: (1) advancing foundational brain and behavior science relevant to mental disorders, (2) strengthening translation and integration between basic neuroscience and clinical research (especially for severe mental illnesses), and (3) emphasizing developmental psychopathology, including mechanisms and trajectories beginning in childhood and adolescence.
What levels of analysis are appropriate for a Conte Center?
The program is aimed at teams that work across different levels of analysis, such as molecules, cells, circuits, behavior, and clinical phenomena, and integrate those levels in a coordinated way.
Is translational research required, and what does translation mean in this context?
The opportunity emphasizes translation and integration between basic neuroscience and clinical research. In this context, translation refers to connecting mechanistic discoveries to human symptoms, clinical trajectories, or treatment-relevant targets, particularly for severe mental illnesses.
How does the program address developmental psychopathology?
The program encourages research that clarifies neurobehavioral developmental mechanisms and trajectories that lead to psychopathology beginning in childhood and adolescence, including how early biological and behavioral processes evolve over time into later risk or disorder.
Why does NIMH emphasize that the center should be “greater than the sum of its parts”?
A key screening concept is that Conte Centers are intended for unusually complex or integrative programs where the combined approach enables discoveries that could not realistically be achieved if the components were funded or executed separately.
Are Conte Centers expected to include shared resources?
Yes. The description indicates that projects and shared resources should be coordinated around a central set of questions, as part of a tightly integrated center structure.
Does this program include a training or workforce-development expectation?
Yes. Conte Centers are expected to provide interdisciplinary basic and/or translational research experiences for individuals in training, using the center environment to expose trainees to cross-cutting methods and collaborative practices that span basic and clinical neuroscience.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and governmental entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status, as specified), small businesses, and for-profit organizations other than small businesses, along with various levels of government and other entities listed in the announcement summary.
Are government entities eligible to apply?
Yes. The eligibility list includes state, county, and city or township governments; special district governments; independent school districts; and public housing authorities/Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility language explicitly includes federally recognized Native American tribal governments and other tribal organizations.
Are minority-serving institutions included in eligibility?
Yes. The eligibility language explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly included in the eligibility language.
Are U.S. territories or possessions included in eligibility?
Yes. U.S. territories or possessions are included in the eligibility language.
Are federal agencies eligible applicants under this opportunity?
Yes. The eligibility language includes eligible federal agencies.
Is cost sharing or matching required?
No. The opportunity states that it does not require cost sharing or matching.
When was this opportunity posted?
The posting date listed is February 16, 2011.
What were the closing and archive dates for this announcement?
The original and current closing date listed is May 25, 2013, and the archive date is June 25, 2013.
Is this funding opportunity currently open?
Based on the provided dates (closing date in 2013 and archive date in 2013), this specific posting is described as historical rather than currently open under that announcement.
Where can applicants find the official full announcement text?
The opportunity points to the NIH Grants Guide page for PAR-11-126 at http://grants.nih.gov/grants/guide/pa-files/PAR-11-126.html.
Who should be contacted for technical issues accessing or linking to the announcement?
The listing provides NIH Office of Extramural Research (OER) webmaster contact information for technical access or linking issues.
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