Opportunity Information: Apply for RFA RM 12 007
Apply for RFA RM 12 007
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Human Heredity and Health in Africa (H3Africa) H3Africa Research Grants (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.279 Drug Abuse and Addiction Research Programs 93.310 Trans NIH Research Support 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Oct 26, 2012 and posted on Aug 22, 2012.
- Applicants must submit their applications by Oct 31, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,400,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Organizations) Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Human Heredity and Health in Africa (H3Africa) H3Africa Research Grants (U01) opportunity (Funding Opportunity Number RFA-RM-12-007) is a National Institutes of Health (NIH) funding announcement that supports research projects led by institutions based in African countries. It is backed by the NIH Common Fund along with participating NIH Institutes and Centers, and it is part of the broader H3Africa initiative, which NIH runs in partnership with the Wellcome Trust. The central aim is to fund cooperative agreement research projects (U01 mechanism) that advance H3Africa goals by using modern genomic approaches to study how genetic, genomic, and environmental factors contribute to health and disease in African populations, while also strengthening long-term research capacity across the continent.
A key theme of the program is that it is not only about producing scientific findings, but also about building sustainable genomics and biomedical research ecosystems within Africa. Applicants are expected to propose projects that use cutting-edge genomic research tools and that help develop the infrastructure needed for high-quality genomics research. This can include building or strengthening data resources, research resources, and broader enabling infrastructure that supports genomic studies. In addition, the FOA emphasizes growing human capital by improving genomic proficiency among African researchers and trainees, indicating that projects should meaningfully contribute to training, skills development, and the ability of local institutions to independently conduct advanced genomics research over time.
The award mechanism is a cooperative agreement (U01), which typically indicates substantial scientific or programmatic involvement by NIH staff during the life of the project, beyond what is common for a standard grant. In practice, that usually means awardees may be expected to coordinate closely with NIH and align with H3Africa consortium practices, policies, or shared resources, consistent with the initiative’s continent-wide capacity-building and collaboration goals.
From an administrative standpoint, this is a discretionary funding opportunity categorized under Education, Health, Income Security and Social Services, with CFDA numbers that reflect NIH program areas relevant to genomics and health research: 93.172 (Human Genome Research), 93.279 (Drug Abuse and Addiction Research Programs), 93.310 (Trans-NIH Research Support), 93.853 (Neurosciences and Neurological Disorders), and 93.865 (Child Health and Human Development Extramural Research). The posted date was August 22, 2012, with creation on October 26, 2012. The original closing date was October 29, 2012, later updated to October 31, 2012, and the archive date was November 30, 2012.
In terms of funding size, the opportunity lists an estimated total funding amount of $1,400,000 and an award ceiling of $350,000. It also specifies that there is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal matching funds as a condition of receiving an award.
Eligibility is structured to prioritize African leadership and institutional participation. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, with additional eligibility clarified in the full text. Importantly, non-U.S. entities (foreign organizations and foreign institutions) are explicitly eligible to apply, non-U.S. components of U.S. organizations may apply, and foreign components (as defined by NIH policy) are allowed. The announcement specifically highlights that applications are invited from institutions in African countries, aligning the eligibility framework with the initiative’s goal of strengthening Africa-based research capacity and leadership.
For applicants seeking the full official requirements, instructions, and any initiative-specific expectations, the opportunity links to the NIH FOA page at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-007.html. For access issues or broken links, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): H3Africa Research Grants (U01) - RFA-RM-12-007
What is this grant opportunity?
This opportunity is the Human Heredity and Health in Africa (H3Africa) H3Africa Research Grants (U01) funding announcement from the National Institutes of Health (NIH), Funding Opportunity Number RFA-RM-12-007. It supports research projects led by institutions based in African countries.
Which organization is offering this funding?
The funding announcement is issued by the National Institutes of Health (NIH). It is backed by the NIH Common Fund along with participating NIH Institutes and Centers.
What larger initiative does this opportunity belong to?
This FOA is part of the broader H3Africa initiative, which NIH runs in partnership with the Wellcome Trust.
What is the main goal of the H3Africa Research Grants (U01) program?
The central aim is to fund cooperative agreement research projects that advance H3Africa goals by using modern genomic approaches to study how genetic, genomic, and environmental factors contribute to health and disease in African populations, while strengthening long-term research capacity across Africa.
What types of research approaches are encouraged?
Projects are expected to use modern, cutting-edge genomic research tools and approaches focused on understanding how genetic, genomic, and environmental factors influence health and disease in African populations.
Is this opportunity only about research results, or also about capacity building?
It is explicitly both. The program emphasizes producing scientific findings while also building sustainable genomics and biomedical research ecosystems within Africa.
What kinds of capacity-building activities are expected in proposed projects?
Applicants are expected to propose projects that help develop or strengthen infrastructure needed for high-quality genomics research. Examples named in the opportunity include building or strengthening data resources, research resources, and broader enabling infrastructure that supports genomic studies.
Does the FOA include expectations related to training and workforce development?
Yes. The announcement emphasizes growing human capital by improving genomic proficiency among African researchers and trainees. Proposed projects are expected to contribute meaningfully to training, skills development, and the ability of local institutions to independently conduct advanced genomics research over time.
What award mechanism is used for this opportunity?
The award mechanism is a cooperative agreement (U01).
What does it mean that this is a cooperative agreement (U01)?
A cooperative agreement (U01) typically indicates substantial scientific or programmatic involvement by NIH staff during the life of the project, beyond what is common for a standard grant.
What kind of NIH involvement should applicants expect during the project?
Based on the description provided, awardees may be expected to coordinate closely with NIH and align with H3Africa consortium practices, policies, or shared resources, consistent with the initiative's collaboration and capacity-building goals.
What is the estimated total funding amount for this opportunity?
The opportunity lists an estimated total funding amount of $1,400,000.
What is the award ceiling?
The award ceiling is $350,000.
Is cost sharing or matching required?
No. The opportunity specifies that there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal matching funds as a condition of receiving an award.
What is the general funding category for this opportunity?
It is described as a discretionary funding opportunity categorized under Education, Health, Income Security and Social Services.
What CFDA program numbers are associated with this FOA?
The CFDA numbers listed are 93.172 (Human Genome Research), 93.279 (Drug Abuse and Addiction Research Programs), 93.310 (Trans-NIH Research Support), 93.853 (Neurosciences and Neurological Disorders), and 93.865 (Child Health and Human Development Extramural Research).
Who is eligible to apply?
Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, with additional eligibility clarified in the full text. The announcement highlights that applications are invited from institutions in African countries.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. entities (foreign organizations and foreign institutions) are explicitly eligible to apply.
Can non-U.S. components of U.S. organizations apply?
Yes. The opportunity states that non-U.S. components of U.S. organizations may apply.
Are foreign components allowed under NIH policy?
Yes. Foreign components (as defined by NIH policy) are allowed under this announcement.
Is African leadership a priority in this program?
Yes. Eligibility and program framing prioritize African leadership and institutional participation, and the FOA specifically highlights that applications are invited from institutions in African countries.
When was this funding opportunity posted and created?
The posted date was August 22, 2012, and the opportunity was created on October 26, 2012.
What was the application closing date?
The original closing date was October 29, 2012, and it was later updated to October 31, 2012.
When was the opportunity archived?
The archive date was November 30, 2012.
Where can applicants find the official FOA instructions and requirements?
The opportunity links to the NIH FOA page at: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-007.html
Who should be contacted if the FOA link is broken or there are access issues?
The contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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