Opportunity Information: Apply for RFA OD 16 012
Apply for RFA OD 16 012
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Resource Cooperative Agreement (U42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351,.
- This funding opportunity was created on May 24, 2016 and posted on May 24, 2016.
- Applicants must submit their applications by Aug 01, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The grant opportunity titled "Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Resource Cooperative Agreement (U42)" (Funding Opportunity Number RFA-OD-16-012) is a National Institutes of Health (NIH) funding announcement that supports targeted, practical upgrades to the physical infrastructure used for animal model research. Rather than funding brand-new standalone centers or entirely new programs, this announcement is specifically designed for organizations that already hold an active NIH Resource Cooperative Agreement award under the U42 mechanism with participating NIH Institutes and Centers. In other words, it is a revision opportunity: it provides a way for currently funded NIH animal-model-related resource centers to request additional support to strengthen or modernize the facilities and equipment that underpin their research services.
The main purpose of the revision is to improve the built environment and core capabilities that enable high-quality animal model research. The requested improvements can be tailored to the specific needs of the investigators and user communities associated with the funded Center. As a result, the scope can vary widely between applicants. Some revisions may focus on acquiring specialized equipment that directly enhances animal research capacity, quality, efficiency, or safety. Others may emphasize more substantial changes such as alteration and renovation (A and R) projects, which can include physical modifications to existing spaces to better support animal housing, procedures, environmental control, workflow, containment, or other operational requirements that are critical to maintaining reliable and reproducible animal model research. The emphasis is on infrastructure improvements that meaningfully enhance research capability, not simply routine replacements or minor upgrades without a strong scientific or operational justification.
A notable expectation in this announcement is the encouragement of sustainable facility planning. Applicants are expected to propose designs that are durable and operationally sustainable over time, and to incorporate green technologies where feasible. This typically implies attention to energy efficiency, responsible resource use, and modern facility approaches that reduce long-term operating costs while maintaining or improving animal welfare and research performance. In animal research environments, where ventilation, temperature control, water systems, and sanitation can be resource-intensive, sustainable design and green technology choices can have a significant impact, so the FOA signals that NIH is looking for projects that modernize infrastructure with long-term stewardship in mind.
Administratively, this is a discretionary funding opportunity administered by the U.S. Department of Health and Human Services through NIH (Agency listed as HHS-NIH11). The funding instrument is a Cooperative Agreement, which generally indicates a substantial level of involvement or partnership from NIH staff compared with a standard grant, especially in areas like milestones, oversight, coordination, or programmatic input. The activity category is Health, and the CFDA numbers associated with the opportunity are 93.351 (as listed). The opportunity was created and posted on May 24, 2016, with an application closing date of August 1, 2016 (original and current closing dates are the same in the source data). While the source fields for award ceiling and expected awards are blank in the provided data, the intent of the announcement is clearly focused on enabling impactful infrastructure improvements through revision requests to existing U42 resource awards.
Eligibility is broad in terms of institution type, but it is constrained by the key requirement that applicants must be eligible to submit a revision to an active NIH Resource Cooperative Agreement (U42) from participating NIH Institutes and Centers. The eligible applicant categories listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (as specified), and other entities as described in the FOA's additional eligibility language. Practically, the organizations best positioned for this opportunity are those already operating NIH-supported animal model resource centers under U42 and seeking to address clearly defined infrastructure limitations or modernization needs that, once resolved, would strengthen the research support they provide to investigators.
Overall, the opportunity is best understood as a focused NIH initiative to keep key animal model research resources current, capable, and sustainable by funding well-justified equipment acquisitions and facility modifications that directly improve the quality and effectiveness of animal model research supported by existing U42 cooperative agreements.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "Improving Physical Infrastructure to Enhance Animal Model Research: Revisions of Resource Cooperative Agreement (U42)" and the Funding Opportunity Number is RFA-OD-16-012.
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) funding announcement administered by the U.S. Department of Health and Human Services (HHS). The agency listing provided is HHS-NIH11.
What type of funding mechanism is used?
The funding instrument is a Cooperative Agreement under the U42 mechanism. A cooperative agreement typically implies substantial NIH involvement compared with a standard grant, such as programmatic input, coordination, oversight, and/or milestone-related engagement.
Is this opportunity for new centers or new programs?
No. This announcement is not intended to fund brand-new standalone centers or entirely new programs. It is designed as a revision opportunity for organizations that already have an active NIH Resource Cooperative Agreement award under the U42 mechanism with participating NIH Institutes and Centers.
What does it mean that this is a "revision" opportunity?
It means eligible organizations can request additional support as a revision to an existing active U42 resource award. The intent is to strengthen or modernize facilities and equipment that support the center's existing animal-model-related research services.
What is the main purpose of the requested revisions?
The main purpose is to improve the physical infrastructure (the built environment and related core capabilities) that enables high-quality animal model research. Improvements should meaningfully enhance research capability, quality, efficiency, and/or safety for the supported animal model research activities.
What kinds of projects can be supported under this opportunity?
Based on the description provided, supported projects can include targeted, practical upgrades such as specialized equipment acquisitions and alteration and renovation (A and R) efforts that modify existing spaces to better support animal model research operations.
What is meant by alteration and renovation (A and R) in this context?
A and R refers to physical modifications to existing spaces. Examples described include changes to support animal housing, procedures, environmental control, workflow, containment, and other operational needs that are critical for reliable and reproducible animal model research.
Are equipment purchases allowed, and what is the focus for equipment?
Yes. The announcement contemplates acquiring specialized equipment when it directly enhances animal research capacity, quality, efficiency, or safety, and when it is well-justified in terms of scientific and/or operational need.
Are routine replacements or minor upgrades likely to fit this announcement?
The emphasis is on infrastructure improvements that meaningfully enhance research capability. The description indicates the opportunity is not aimed at routine replacements or minor upgrades that lack strong scientific or operational justification.
How flexible is the scope of proposed infrastructure improvements?
The scope can vary widely between applicants because improvements can be tailored to the needs of the investigators and user communities associated with the funded center. Proposals may range from equipment-focused improvements to more substantial facility modifications.
What is the role of sustainability and green technologies in proposed projects?
Sustainable facility planning is specifically encouraged. Applicants are expected to propose designs that are durable and operationally sustainable over time, and to incorporate green technologies where feasible, implying attention to energy efficiency, responsible resource use, and approaches that can reduce long-term operating costs while maintaining or improving animal welfare and research performance.
Why does the announcement highlight sustainability for animal research environments?
The description notes that animal research environments can be resource-intensive (for example, ventilation, temperature control, water systems, and sanitation). Sustainable design and green technology choices can have significant impact in these settings, so the FOA signals interest in modernization that supports long-term stewardship.
Who is eligible to apply?
Eligibility is broad by institution type but constrained by a key requirement: the applicant must be eligible to submit a revision to an active NIH Resource Cooperative Agreement (U42) from participating NIH Institutes and Centers. Eligible categories listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (as specified), and other entities as described in the FOA's additional eligibility language.
Does an organization need to already have an active U42 award to apply?
Yes. The opportunity is specifically designed for organizations that already hold an active NIH Resource Cooperative Agreement award under the U42 mechanism (with participating NIH Institutes and Centers) and are submitting a revision request to that active award.
What types of organizations are most practically positioned for this opportunity?
Practically, organizations already operating NIH-supported animal model resource centers under U42 and seeking to address clearly defined infrastructure limitations or modernization needs are best positioned, since the mechanism is a revision to an existing U42 resource award.
What is the activity category for this funding opportunity?
The activity category is Health.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.351.
When was the opportunity created and posted?
The opportunity was created and posted on May 24, 2016.
What is the application closing date?
The application closing date is August 1, 2016. The provided information indicates the original and current closing dates are the same.
Is the award ceiling or the number of expected awards specified in the provided information?
No. In the provided data, the fields for award ceiling and expected awards are blank.
What is the overall intent of this NIH initiative?
The overall intent is to keep key animal model research resources current, capable, and sustainable by funding well-justified equipment acquisitions and facility modifications that directly improve the quality and effectiveness of animal model research supported by existing U42 cooperative agreements.
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