Opportunity Information: Apply for PA 12 132
Apply for PA 12 132
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Improving Translational and Basic Research to Control Itch in Humans (ITCH) (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research.
- This funding opportunity was created on Mar 20, 2012 and posted on Mar 20, 2012.
- Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Special district governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses City or township governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The grant opportunity titled "Improving Translational and Basic Research to Control Itch in Humans (ITCH) (R21)" (Funding Opportunity Number PA 12-132) is a National Institutes of Health (NIH) discretionary grant designed to push forward research on itch, a symptom that has historically received less attention than pain despite its major impact on quality of life. The announcement focuses on both basic and translational science, meaning it encourages projects that uncover fundamental biological mechanisms of itch while also moving those insights toward practical ways to reduce, regulate, or prevent itch in real-world disease and rehabilitation settings. The overall intent is to speed up progress in what the FOA describes as a relatively nascent field and to translate emerging discoveries into improvements in human health that align with the mission of the NIH institute supporting this area, particularly conditions involving arthritis, musculoskeletal, and skin diseases.
A central theme of the FOA is understanding how itch is generated, transmitted, and perceived, and then using that knowledge to develop methods to modulate itch. This can include studying the pathways and signals involved in itch sensation, identifying targets that could be influenced by drugs or other interventions, and exploring how itch changes across different diseases or physiological states. The announcement explicitly supports a wide range of experimental approaches, including work in animal models and human models, and it places special value on multidisciplinary collaboration. In practice, that means the program is looking for teams and projects that combine perspectives such as neuroscience, immunology, dermatology, rehabilitation science, molecular biology, pharmacology, bioengineering, or computational methods, with the goal of enabling rapid back-and-forth learning between laboratory findings and clinically relevant questions. The emphasis on "bench to bedside exchange" signals a preference for research that is not isolated within one domain, but instead is structured so that mechanistic discoveries can quickly inform therapeutic concepts, measurement tools, or strategies for itch control.
The funding mechanism is the NIH R21, which is commonly used for exploratory and developmental research. In line with that purpose, this opportunity is well-suited for early-stage ideas, proof-of-concept studies, and projects that test innovative hypotheses or emerging methodologies that could open up new directions in itch research. The award ceiling listed for this FOA is $200,000, and the opportunity states there is no cost sharing or matching requirement, which reduces the need for applicants to bring non-federal funds to the table.
At the same time, the FOA draws a clear boundary around what it will not fund: it is not intended to support clinical trials. Applicants can still propose studies that are human-relevant or human-based, but they need to stay within the scope of basic or translational research that does not cross into clinical trial territory as defined by NIH. In practical terms, that typically means focusing on mechanistic studies, observational or experimental work that does not assign participants to interventions for the purpose of evaluating health outcomes, development of tools or assays, preclinical testing, and other non-trial translational activities.
Eligibility is broad and intentionally inclusive, spanning many types of domestic U.S. organizations and also allowing foreign participation. Eligible applicants include public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3) in certain cases), for-profit organizations (other than small businesses) as well as small businesses, and multiple levels of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also highlights eligibility for a wide range of institutions and organizations often emphasized in federal research programs, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), tribal organizations (including federally recognized tribal governments and other tribal entities), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Non-domestic (non-U.S.) entities are explicitly eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined in the NIH Grants Policy Statement.
From an administrative standpoint, the opportunity is categorized under Health, with CFDA number 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research). The FOA was posted and created on March 20, 2012, and the original and current closing date listed is May 7, 2015, with an archive date of June 7, 2015, indicating the announcement is no longer active but remains available as a record. For full details, NIH provided an additional information link to the official FOA page, and for access or technical issues, the NIH Office of Extramural Research (OER) webmaster contact is provided (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
What is the official title and funding opportunity number for this grant?
The opportunity is titled "Improving Translational and Basic Research to Control Itch in Humans (ITCH) (R21)" and the Funding Opportunity Number is PA 12-132.
Which agency is offering this grant?
This is a National Institutes of Health (NIH) discretionary grant opportunity.
What is the main purpose of this funding opportunity?
The FOA is designed to accelerate progress in itch research by supporting both basic and translational projects. The emphasis is on understanding how itch is generated, transmitted, and perceived, and using that knowledge to develop ways to reduce, regulate, or prevent itch in real-world disease and rehabilitation settings.
What kinds of research does the FOA encourage?
The announcement encourages a range of basic and translational science approaches, including work that uncovers fundamental biological mechanisms of itch as well as research that moves emerging discoveries toward practical strategies for itch control that are relevant to human health.
What topic areas are especially aligned with this FOA?
The FOA aligns with NIH interests in conditions involving arthritis, musculoskeletal diseases, and skin diseases, with itch as a major symptom affecting quality of life.
Is this opportunity focused only on basic science or only on clinical applications?
No. A central feature of this FOA is the combination of basic and translational research, encouraging "bench to bedside" exchange where mechanistic discoveries can inform clinically relevant concepts, tools, or strategies for controlling itch.
Does the FOA support multidisciplinary research teams?
Yes. The FOA places special value on multidisciplinary collaboration and encourages combining perspectives such as neuroscience, immunology, dermatology, rehabilitation science, molecular biology, pharmacology, bioengineering, and computational methods.
Are animal models allowed under this FOA?
Yes. The FOA explicitly supports work in animal models.
Are human-based studies allowed under this FOA?
Yes. The FOA explicitly supports work in human models and other human-relevant approaches, as long as the proposed work stays within the boundaries described by the FOA (not intended to support clinical trials).
Does this funding opportunity allow clinical trials?
No. The FOA states it is not intended to support clinical trials. Projects can still be human-relevant or human-based, but they must remain within the scope of basic or translational research that does not cross into clinical trial territory as defined by NIH.
What kinds of activities fit the non-clinical-trial boundary described in the FOA?
Based on the FOA description, suitable activities include mechanistic studies, observational or experimental work that does not assign participants to interventions for the purpose of evaluating health outcomes, development of tools or assays, and preclinical testing, among other non-trial translational efforts.
What grant mechanism is used for this opportunity?
The funding mechanism is the NIH R21, which is commonly used for exploratory and developmental research.
What types of projects are a good fit for an R21 under this FOA?
The FOA describes this opportunity as well-suited for early-stage ideas, proof-of-concept studies, and exploratory projects that test innovative hypotheses or emerging methodologies that could open new directions in itch research.
What is the award ceiling for this FOA?
The award ceiling listed is $200,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many types of domestic U.S. organizations as well as foreign participation. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations), for-profit organizations (including small businesses), and multiple levels of government entities such as state, county, and city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are small businesses eligible?
Yes. The FOA includes small businesses among eligible applicants.
Are for-profit organizations eligible?
Yes. The FOA includes for-profit organizations (other than small businesses) and also includes small businesses as eligible.
Are nonprofits eligible?
Yes. The FOA includes nonprofits, including 501(c)(3) organizations and certain non-501(c)(3) organizations.
Are government entities eligible to apply?
Yes. The FOA lists multiple government entities as eligible, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are minority-serving institutions and similar organizations specifically included?
Yes. The FOA highlights eligibility for Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and other institutions and organizations often emphasized in federal research programs.
Are tribal organizations eligible?
Yes. The FOA includes tribal organizations, including federally recognized tribal governments and other tribal entities.
Are faith-based or community-based organizations eligible?
Yes. The FOA highlights eligibility for faith-based and community-based organizations.
Are U.S. territories or possessions included in eligibility?
Yes. The FOA mentions U.S. territories or possessions as included.
Can foreign (non-U.S.) organizations apply?
Yes. Non-domestic (non-U.S.) entities are explicitly eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
Yes. The FOA states that non-U.S. components of U.S. organizations are eligible.
Are foreign components allowed?
Yes. The FOA states that foreign components are allowed as defined in the NIH Grants Policy Statement.
What is the CFDA number and program area for this opportunity?
The opportunity is categorized under Health with CFDA number 93.846, listed as Arthritis, Musculoskeletal and Skin Diseases Research.
When was this FOA posted?
The FOA was posted (and created) on March 20, 2012.
What were the closing dates for this opportunity?
The original and current closing date listed is May 7, 2015.
Is this funding opportunity still active?
No. The archive date is June 7, 2015, which indicates the announcement is no longer active and is available as a record.
Where can applicants find the official FOA and full details?
NIH provided an additional information link to the official FOA page for full details.
Who should be contacted for access or technical issues related to the FOA?
For access or technical issues, the FOA provides the NIH Office of Extramural Research (OER) webmaster contact: FBOWebmaster@OD.NIH.GOV.
Browse more opportunities from the same category: Health
Next opportunity: Notice of Intent to Award Moton Museum
Previous opportunity: Improving Translational and Basic Research to Control Itch in Humans (ITCH) (R01)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 12 132
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PA 12 132) also looked into and applied for these:
| Funding Opportunity |
|---|
| Provision of Comprehensive HIV/AIDS Services and Developing National Capacity to Manage HIV/AIDS Programs in the Republic of Uganda under the Presidents Plan for AIDS Relief Apply for CDC RFA GH12 1213 Funding Number: CDC RFA GH12 1213 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $3,588,471 |
| State Public Health Approaches to Improving Arthritis Outcomes Apply for CDC RFA DP12 1210 Funding Number: CDC RFA DP12 1210 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $500,000 |
| Coordinating Center for Research and Training to Promote the Health of People with Developmental and Other Disabilities Apply for RFA DD 12 006 Funding Number: RFA DD 12 006 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,700,000 |
| Primary Care Training and Enhancement Physician Assistant Training in Primary Care Program Apply for HRSA 12 024 Funding Number: HRSA 12 024 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Validating Data found in Linked 2003 Version of Vital Records and Hospital Discharge Data for Quality Improvement in the States Apply for CDC RFA DP12 1201 Funding Number: CDC RFA DP12 1201 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $125,000 |
| HIV Early Intervention Services (EIS) Program Limited Competitive Service Areas (San Francisco, CA and Columbia, SC) Apply for HRSA 12 175 Funding Number: HRSA 12 175 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Cardiovascular Risk Reduction in Underserved Rural Communities (R01) Apply for RFA HL 13 013 Funding Number: RFA HL 13 013 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Children and Adults with Attention Deficit Hyperactivity Disorder (CHADD) Apply for CDC RFA DD07 7140501SUPP12 Funding Number: CDC RFA DD07 7140501SUPP12 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Advanced Education Nursing Traineeship (AENT) Program Apply for HRSA 12 062 Funding Number: HRSA 12 062 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Strengthening National Pediatric HIV/AIDS and Scaling up Comprehensive HIV/AIDS Services in the Republic of Uganda under The Presidents Emergency Plan For AIDS Relief Apply for CDC RFA GH12 1215 Funding Number: CDC RFA GH12 1215 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $5,000,000 |
| NHLBI Systems Biology Collaborations (R01) Apply for PAR 12 138 Funding Number: PAR 12 138 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Engaging Indigenous Organizations to Sustain and Enhance Comprehensive Clinical Services for the Prevention, Care and Treatment of HIV/AIDS in the Federal Republic of Nigeria under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH12 1210 Funding Number: CDC RFA GH12 1210 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $160,000,000 |
| Sample Vital Registration with Verbal Autopsy in the the Republic of Zambia under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH12 1245 Funding Number: CDC RFA GH12 1245 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $3,150,000 |
| NHLBI Career Transition Award (K22) Apply for PAR 12 137 Funding Number: PAR 12 137 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Provider Education and Public Awareness about Primary Immunodeficiency Disease Apply for CDC RFA OE12 1203 Funding Number: CDC RFA OE12 1203 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,000,000 |
| Conducting Operational Research to Measure or Mitigate Morbidity And Mortality of Populations Affected by Humanitarian Emergencies Apply for RFA GH 12 007 Funding Number: RFA GH 12 007 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $500,000 |
| Accelerating Delivery of Comprehensive HIV/AIDS/TB services including Prevention, Care, Support and Treatment Adult and Children Living with HIV/AIDS in the Republic of Uganda under the Presidents Emergency Plan for AIDS Relief Apply for CDC RFA GH12 1214 Funding Number: CDC RFA GH12 1214 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $9,600,000 |
| Improving Health of People with Intellectual Disabilities Apply for CDC RFA DD12 1201 Funding Number: CDC RFA DD12 1201 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $3,500,000 |
| Advanced Nursing Education Program Apply for HRSA 12 061 Funding Number: HRSA 12 061 Agency: Health Resources and Services Administration Category: Health Funding Amount: $375,000 |
| Behavioral and Serological Survey for HIV and Syphilis Among Diamond Mine Workers in Angola Apply for CDC RFA GH12 1254 Funding Number: CDC RFA GH12 1254 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $750,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 12 132", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.