Opportunity Information: Apply for RFA RM 09 004
Apply for RFA RM 09 004
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Institutional Clinical and Translational Science Award (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support 93.389 National Center for Research Resources.
- This funding opportunity was created on Jan 7, 2009 and posted on Jan 7, 2009.
- Applicants must submit their applications by Oct 14, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $20,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education State governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Institutional Clinical and Translational Science Award (CTSA) (U54) is a National Institutes of Health (NIH) cooperative agreement designed to help institutions build and sustain an integrated, campus-wide "home" for clinical and translational science. The central idea is to strengthen the infrastructure, training environment, and collaborative culture needed to move discoveries more efficiently from basic research into real-world patient care and community health practice. Rather than supporting a single research project, this opportunity is aimed at creating an institutional hub that brings people, tools, and systems together so that translational work can be done faster, more rigorously, and across disciplinary boundaries.
A major focus of the CTSA initiative is workforce development and team science. The award emphasizes training and advancing multi- and interdisciplinary investigators and research teams, with particular attention to providing access to innovative research tools and modern information technologies. The program is meant to attract and connect a wide range of partners, including basic scientists, translational researchers, clinical investigators, community clinicians, clinical practices and care networks, professional societies, and industry. By drawing these groups into shared programs and collaborative research efforts, CTSAs are intended to spark new professional relationships and create the conditions for new projects that directly improve clinical care and health outcomes.
The opportunity also highlights education and degree-based training as a key mechanism for building the field itself. Through innovative advanced degree programs, CTSAs are expected to foster clinical and translational science as a distinct discipline that is broader and deeper than any single component (basic, translational, or clinical research alone). In practice, that means supporting structured curricula, mentored experiences, and career development pathways that prepare investigators to navigate the full translational spectrum, work effectively in cross-functional teams, and apply new methods and technologies to patient-oriented research.
From an administrative standpoint, this is a discretionary NIH funding opportunity using a cooperative agreement mechanism (U54), which typically means NIH expects substantial involvement and partnership in program oversight compared to a standard grant. The Funding Opportunity Number is RFA-RM-09-004, and it was posted on January 7, 2009, with an application closing date of October 14, 2009 (archived November 14, 2009). The estimated total funding amount listed is $20,000,000, and there is no cost sharing or matching requirement.
Eligibility is broad and includes public and private institutions of higher education, state governments, U.S. territories or possessions, tribal governments (federally recognized and other-than-federally recognized as specified), tribally controlled colleges and universities, regional organizations, certain nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), and for-profit organizations other than small businesses. The announcement explicitly notes inclusion of institutions serving specific populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and other eligible tribal and tribally controlled entities. Two CFDA numbers are associated with the opportunity: 93.310 (Trans-NIH Research Support) and 93.389 (National Center for Research Resources).
For applicants or interested institutions, the full announcement was provided through an NIH Grants Guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-09-004.html). For technical access issues, NIH directed inquiries to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): Institutional Clinical and Translational Science Award (CTSA) (U54)
What is the Institutional Clinical and Translational Science Award (CTSA) (U54)?
The Institutional Clinical and Translational Science Award (CTSA) (U54) is a National Institutes of Health (NIH) cooperative agreement intended to help institutions build and sustain an integrated, campus-wide "home" for clinical and translational science.
What is the main purpose of this CTSA opportunity?
The central purpose is to strengthen the institutional infrastructure, training environment, and collaborative culture needed to move discoveries more efficiently from basic research into real-world patient care and community health practice.
Is this funding meant to support a single research project?
No. This opportunity is not focused on one discrete research project. It is aimed at creating an institutional hub that brings people, tools, and systems together to enable translational work to be done faster, more rigorously, and across disciplinary boundaries.
What does it mean that CTSA is an institutional "hub" or "home" for translational science?
It means the award is intended to support a coordinated, campus-wide structure that integrates programs, personnel, technologies, and collaborative processes so clinical and translational science can operate as a connected enterprise rather than separate, siloed activities.
What are the major programmatic focus areas highlighted in the description?
Key focus areas include workforce development, team science, training and advancement of multi- and interdisciplinary investigators and research teams, and providing access to innovative research tools and modern information technologies.
How does the CTSA initiative address workforce development and team science?
The award emphasizes training and advancing investigators and research teams that work across disciplines, encouraging multi- and interdisciplinary approaches and supporting access to tools and information technologies that enable modern translational research.
What kinds of partners is the CTSA program designed to attract and connect?
The program is intended to attract and connect a wide range of partners, including basic scientists, translational researchers, clinical investigators, community clinicians, clinical practices and care networks, professional societies, and industry.
Why does the CTSA program emphasize collaboration among diverse partners?
By drawing multiple stakeholder groups into shared programs and collaborative research efforts, CTSAs are intended to spark new professional relationships and create conditions for new projects that directly improve clinical care and health outcomes.
What role do education and degree-based training play in this opportunity?
Education and degree-based training are described as key mechanisms for building the field of clinical and translational science. The CTSA is expected to support innovative advanced degree programs and structured training pathways.
How does this opportunity describe clinical and translational science as a discipline?
The opportunity frames clinical and translational science as a distinct discipline that is broader and deeper than any single component (basic research, translational research, or clinical research alone).
What types of training elements are mentioned?
Examples of training elements include structured curricula, mentored experiences, and career development pathways that prepare investigators to work across the full translational spectrum and function effectively in cross-functional teams.
What funding mechanism is used for this opportunity?
This is a discretionary NIH funding opportunity using a cooperative agreement mechanism (U54).
What does "cooperative agreement (U54)" imply about NIH involvement?
A cooperative agreement (U54) typically indicates substantial involvement and partnership by NIH in program oversight compared to a standard grant.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is RFA-RM-09-004.
When was this funding opportunity posted and when did it close?
It was posted on January 7, 2009. The application closing date was October 14, 2009, and the opportunity was archived on November 14, 2009.
What is the estimated total funding amount listed for this opportunity?
The estimated total funding amount listed is $20,000,000.
Is there a cost sharing or matching requirement?
No. The opportunity states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, state governments, U.S. territories or possessions, tribal governments (federally recognized and other-than-federally recognized as specified), tribally controlled colleges and universities, regional organizations, certain nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), and for-profit organizations other than small businesses.
Are institutions serving specific populations explicitly included?
Yes. The announcement explicitly notes inclusion of institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and other eligible tribal and tribally controlled entities.
What CFDA numbers are associated with this CTSA opportunity?
Two CFDA numbers are associated with the opportunity: 93.310 (Trans-NIH Research Support) and 93.389 (National Center for Research Resources).
Where can applicants find the full official announcement?
The full announcement was provided through the NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-09-004.html
Who should be contacted for technical access issues related to the announcement?
For technical access issues, NIH directed inquiries to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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