Intellectual and Developmental Disabilities Research Centers 2013 (U54) | Apply Online

Opportunity Summary:

The Intellectual and Developmental Disabilities Research Centers 2013 (U54) opportunity (Funding Opportunity Number RFA-HD-13-002) is a National Institutes of Health cooperative agreement run through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Its overall goal is to strengthen and expand the national research infrastructure focused on intellectual and developmental disabilities (IDD) by supporting specialized research centers, called IDDRCs, that can push the field forward in practical ways. The program is aimed at accelerating progress across the full pipeline of IDD science, from basic discovery through translational and clinical work, with the end goals of improving diagnosis, preventing or reducing disability where possible, developing better treatments, and improving daily functioning and quality of life for people with IDD.

A central feature of this FOA is that applicants are expected to propose a true multidisciplinary center program rather than a collection of unrelated projects. The center is built around shared scientific resources and expertise, organized as cores, that enable interdisciplinary and translational research. These cores are meant to serve as the backbone of the center by providing services, technologies, participant resources, consultation, and other capabilities that individual investigators can use to conduct IDD-related research more efficiently and at a higher level of rigor. Importantly, these core facilities are designed not only to support projects directly associated with the center, but also to support a broader portfolio of IDD research projects that are funded by other sources. In other words, the U54 mechanism is being used to help create and maintain high-value shared infrastructure so that many studies, potentially supported by federal, state, foundation, or other private funding, can benefit from the same high-quality resources.

In addition to the core infrastructure, the FOA requires the center to include at least one specific research project that aligns with one of five focus themes identified by NICHD as areas of particular research need in IDD. While the summary provided here does not list the five themes by name, the requirement signals that NICHD wanted each funded center to contribute directly to priority gaps in the field, not only by offering services but also by generating new research findings tied to a defined need. The expectation is that the center will use its cores to catalyze cross-disciplinary collaboration and translate advances more rapidly toward outcomes that matter clinically and functionally for individuals with IDD and their families.

From an administrative and funding standpoint, this opportunity falls under the discretionary category and uses the cooperative agreement funding instrument, meaning NIH anticipates substantial programmatic involvement compared with a standard grant. The associated activity category is listed as Health, Income Security and Social Services, and the CFDA number is 93.865 (Child Health and Human Development Extramural Research). The announcement was posted on January 16, 2013, with an original and current closing date of April 9, 2013, and an archive date of May 10, 2013. The estimated total funding level noted in the announcement is $3,900,000, and there is no cost-sharing or matching requirement.

Eligibility is broad across many U.S.-based organization types, reflecting the center-based and infrastructure-building nature of the program. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (including small businesses and for-profits other than small businesses), and a range of government entities such as state governments, county governments, and city or township governments. The FOA also indicates eligibility for public housing authorities/Indian housing authorities, independent school districts, special district governments, and various tribal entities, including federally recognized tribal governments and tribal organizations. The eligibility section further clarifies that Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, faith-based or community-based organizations, and U.S. territories or possessions may be eligible. At the same time, the FOA is explicit that non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as NIH defines them) are not permitted, keeping the program centered on U.S.-based institutional capacity.

In practical terms, an institution applying to this FOA would be proposing to operate a coordinated IDDRC that can serve as a hub for IDD research, offering shared cores that multiple investigators can rely on, while also conducting at least one targeted research project that addresses a NICHD-identified priority theme in IDD. The design reflects a deliberate emphasis on building durable, reusable scientific capability that multiplies the impact of many independently funded studies, while also ensuring that each center makes a direct, visible contribution to high-need research areas. For full details, applicants were directed to the NIH guide notice linked in the announcement at http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-13-002.html, with technical access support available through the NIH Office of Extramural Research webmaster contact listed in the posting.

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