Opportunity Information: Apply for RFA HD 16 013

  • The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Intellectual and Developmental Disabilities Research Centers 2016 (U54)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
  • This funding opportunity was created on Dec 09, 2015 and posted on Dec 09, 2015.
  • Applicants must submit their applications by Feb 18, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $800,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA HD 16 013

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Opportunity Summary:

The Intellectual and Developmental Disabilities Research Centers 2016 (U54) funding opportunity (RFA-HD-16-013) is a federal discretionary grant offered by HHS through NIH (listed as HHS-NIH11) to support the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). The goal is to build and maintain research centers that accelerate progress in intellectual and developmental disabilities (IDD) by improving diagnosis, strengthening prevention strategies, advancing treatment options, and developing approaches that lessen the impact of these conditions across the lifespan. Rather than funding a single stand-alone study, the FOA is structured to support a coordinated, multi-disciplinary center program that can serve as a hub for IDD science and translation into practice.

A key feature of this opportunity is that it uses the U54 cooperative agreement mechanism, which typically implies substantial scientific or programmatic involvement by the NIH beyond what is common in a standard research grant. In practical terms, applicants are expected to propose a center that is capable of organizing shared infrastructure, aligning investigators across disciplines, and supporting a portfolio of IDD research that can move discoveries toward real-world clinical or community benefit. The center model is meant to increase efficiency and impact by concentrating specialized expertise, facilities, and services that individual labs or projects might not be able to sustain on their own.

Applications are expected to include two major components. First, the center must establish one or more “cores,” meaning shared resources and services that facilitate interdisciplinary and translational IDD research. These cores are intended to enable and strengthen a wider range of projects, including studies that are funded by other sources, by providing access to tools, methods, consultation, clinical or community-facing capabilities, data resources, or other centralized supports. Second, the application must include at least one specific research project that directly addresses one of five focus themes identified in the FOA as priority areas of need in IDD research. While the themes themselves are not listed in the text provided here, the structure makes clear that the center must do more than offer infrastructure; it must also carry at least one defined research effort aligned with NIH-identified gaps or priorities.

Another important point in the announcement is that the majority of research projects that use the center’s cores are expected to be supported by independent funding sources, including federal, state, and private organizations. This signals that the IDDRC award is designed primarily to underwrite shared capacity and coordinated center functions, creating an environment where many independently funded IDD projects can be strengthened through access to cores, collaboration, and translational pathways. In other words, the award is meant to multiply the value of existing and future IDD research funding by making it easier for investigators to do high-quality, integrated work using common resources.

Eligibility is broad and includes many types of organizations: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the FOA’s additional eligibility guidance. This wide eligibility reflects the interdisciplinary, cross-sector nature of IDD research and service systems, and it leaves room for academic health centers, research institutes, community-oriented organizations, and other qualified entities to serve as the applicant institution if they can demonstrate the required multi-disciplinary capacity.

Funding details in the source data indicate an award ceiling of $800,000 and an expectation of about five awards. The opportunity was posted and created on December 9, 2015, with an application closing date of February 18, 2016. The activity category is listed under Health, Income Security and Social Services, and the CFDA number associated with the program is 93.865. Overall, this FOA supports a center-based approach intended to strengthen the national IDD research infrastructure by combining shared cores with at least one targeted research project, enabling broader externally funded IDD studies to operate more effectively and with greater translational reach.

Frequently Asked Questions (FAQ)

What is the Intellectual and Developmental Disabilities Research Centers 2016 (U54) opportunity?

This funding opportunity supports the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). It is designed to build and maintain research centers that accelerate progress in intellectual and developmental disabilities (IDD) by improving diagnosis, strengthening prevention strategies, advancing treatment options, and developing approaches that lessen the impact of these conditions across the lifespan.

Who is offering this grant?

The grant is a federal discretionary funding opportunity offered by the U.S. Department of Health and Human Services (HHS) through the National Institutes of Health (NIH), listed as HHS-NIH11.

What is the FOA number for this opportunity?

The Funding Opportunity Announcement (FOA) number is RFA-HD-16-013.

What grant mechanism is used, and why does it matter?

This opportunity uses the U54 cooperative agreement mechanism. A cooperative agreement typically implies substantial scientific or programmatic involvement by NIH beyond what is common in a standard research grant, and applicants are expected to propose a center that can organize shared infrastructure, align investigators across disciplines, and support a portfolio of IDD research that moves discoveries toward clinical or community benefit.

Is this funding meant for a single research study?

No. The FOA is structured to support a coordinated, multi-disciplinary center program that functions as a hub for IDD science and translation into practice, rather than a single stand-alone study.

What is the main goal of an IDDRC under this FOA?

The goal is to build and maintain a research center that increases efficiency and impact by concentrating specialized expertise, facilities, and services, helping investigators across disciplines collaborate and accelerate translational progress in IDD research.

What are the required components of an application?

Applications are expected to include two major components: (1) one or more shared “cores” that provide centralized resources and services supporting interdisciplinary and translational IDD research, and (2) at least one specific research project that directly addresses one of five focus themes identified as priority areas in the FOA.

What are “cores” in the context of this center grant?

Cores are shared resources and services that facilitate interdisciplinary and translational IDD research. They can include tools, methods, consultation, clinical or community-facing capabilities, data resources, or other centralized supports intended to enable and strengthen a range of projects, including projects funded by other sources.

Does the center have to include an actual research project, or can it be infrastructure-only?

The center must do more than offer infrastructure. The application must include at least one defined research project aligned with one of the FOA’s five NIH-identified priority themes.

Are the five focus themes listed in the information provided here?

No. The provided description notes that the FOA identifies five focus themes as priority areas of need, but the themes themselves are not listed in the text provided.

How does this award relate to other research funding?

The FOA indicates that the majority of research projects using the center’s cores are expected to be supported by independent funding sources (including federal, state, and private organizations). This signals the IDDRC award is intended primarily to underwrite shared capacity and coordinated center functions that strengthen many independently funded IDD projects.

What kind of impact is this center model intended to have?

The center model is meant to multiply the value of existing and future IDD research funding by making it easier for investigators to do high-quality, integrated work using common resources, interdisciplinary collaboration, and translational pathways that move research toward real-world benefit.

Who is eligible to apply?

Eligibility is broad and includes: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the FOA’s additional eligibility guidance.

Does the opportunity allow applications from both academic and non-academic organizations?

Yes. The broad eligibility categories reflect the interdisciplinary, cross-sector nature of IDD research and service systems and leave room for academic health centers, research institutes, community-oriented organizations, and other qualified entities to apply if they can demonstrate the required multi-disciplinary capacity.

What is the award ceiling for this opportunity?

The funding details indicate an award ceiling of $800,000.

How many awards are expected?

The opportunity indicates an expectation of about five awards.

When was the opportunity posted, and what was the application deadline?

The opportunity was posted and created on December 9, 2015. The application closing date was February 18, 2016.

What is the CFDA number associated with this program?

The CFDA number associated with the program is 93.865.

How is the activity category classified?

The activity category is listed under Health, Income Security and Social Services.

What is NIH’s expected role under a U54 cooperative agreement in this context?

Because this is a U54 cooperative agreement, NIH is expected to have substantial scientific or programmatic involvement beyond what is typical for a standard research grant. The provided information emphasizes that applicants should plan for a coordinated center structure capable of organizing shared infrastructure and supporting translational, multi-disciplinary research efforts.

What does “translation into practice” mean in the context of this FOA?

Based on the description provided, it refers to a center approach that helps move IDD discoveries toward real-world clinical or community benefit, including progress in diagnosis, prevention strategies, treatment options, and approaches that lessen the impact of IDD across the lifespan.

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