Opportunity Information: Apply for RFA DA 09 013
Apply for RFA DA 09 013
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Interactions between Physical Activity and Drug Abuse (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Oct 16, 2008 and posted on Oct 16, 2008.
- Applicants must submit their applications by Jan 28, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Private institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) State governments County governments City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Interactions between Physical Activity and Drug Abuse (R01) funding opportunity (RFA-DA-09-013) is a National Institutes of Health grant announcement from the National Institute on Drug Abuse (NIDA) focused on how physical activity and exercise influence the brain and behavior in ways that matter for substance abuse. The central aim is to drive research that explains the neurobiological and behavioral mechanisms behind exercise-related changes in brain function across the lifespan, and then use that knowledge to improve prevention and treatment approaches for drug abuse. Projects can use animal models, human subjects, or both, and may look at any brain, behavioral, or cognitive process that is known to be affected by drugs of abuse or by behaviors linked to drug abuse. While studies may involve healthy participants, applicants can also propose work involving people who use substances when that is scientifically justified. A key requirement is that every application clearly connects the proposed work to substance abuse, either by directly improving understanding and/or treatment of drug abuse or by demonstrating how the findings could realistically be implemented in substance-using populations.
The grant uses the NIH R01 mechanism, meaning it is intended for full-scale, hypothesis-driven research projects rather than small pilots. In addition to new R01 applications, the announcement also allows revision applications (formerly called competing supplements or Type 3) to existing R01 grants that involve human subjects, which gives currently funded investigators a pathway to expand an ongoing study into this exercise-substance abuse intersection. This R01 announcement runs alongside a companion FOA with the same scientific scope that uses the R03 mechanism (RFA-DA-09-014), which is generally geared toward smaller, more limited projects.
From a funding and scope standpoint, NIDA planned to commit a total of about $4,000,000 in fiscal year 2009 across this R01 FOA and the companion R03 FOA combined, with an anticipated 8 to 12 total awards. The program falls under CFDA 93.279 (Drug Abuse and Addiction Research Programs) and does not require cost sharing or matching funds. The announcement was posted on October 16, 2008, with an application closing date of January 28, 2009, and it was archived February 28, 2009.
Eligibility is broad and includes many types of institutions and organizations. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, for-profit organizations (including those other than small businesses), state, county, and local governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and tribal governments and organizations (including federally recognized tribes and other tribal entities). The eligibility language also explicitly includes groups such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. (foreign) entities.
In practical terms, this opportunity is designed for research teams that can link exercise science with addiction science, especially teams studying brain systems and behaviors that overlap with substance use risk and recovery. Strong applications under this FOA would not just describe the general health benefits of exercise, but would make a clear, evidence-based case for how the specific physical activity intervention or mechanism being studied relates to drug reward, craving, stress responsivity, cognition, relapse vulnerability, prevention, or treatment engagement and outcomes.
Frequently Asked Questions (FAQs)
What is the funding opportunity called?
The opportunity is titled Interactions between Physical Activity and Drug Abuse (R01) and is identified as RFA-DA-09-013.
Which agency is offering this grant?
This is a National Institutes of Health (NIH) funding opportunity from the National Institute on Drug Abuse (NIDA).
What is the main goal of this FOA?
The central goal is to support research on how physical activity and exercise influence the brain and behavior in ways that are relevant to substance abuse, with the intent of using that knowledge to improve prevention and treatment approaches.
What kinds of research questions does this FOA emphasize?
The FOA emphasizes research that explains the neurobiological and behavioral mechanisms behind exercise-related changes in brain function across the lifespan, specifically in ways that matter for understanding, preventing, or treating drug abuse.
Does the project have to be directly about drug abuse?
Yes. A key requirement is that every application clearly connects the proposed work to substance abuse. The project must either (1) directly improve understanding and/or treatment of drug abuse, or (2) show how findings could realistically be implemented in substance-using populations.
Can studies include healthy participants, or must they include people who use substances?
Studies may involve healthy participants. Applications can also propose work involving people who use substances when scientifically justified. Regardless of the population studied, the application must clearly link the work to substance abuse relevance.
Are animal studies allowed?
Yes. Projects may use animal models, human subjects, or both.
What types of outcomes or processes can be studied?
Projects may examine any brain, behavioral, or cognitive process known to be affected by drugs of abuse or by behaviors linked to drug abuse. The FOA’s intent is that these processes be studied in the context of how exercise changes brain function and behavior in substance abuse-relevant ways.
Is this grant meant for pilot studies or full-scale projects?
This FOA uses the NIH R01 mechanism, which is intended for full-scale, hypothesis-driven research projects, not small pilot work.
Are revision applications allowed?
Yes. In addition to new R01 applications, the announcement allows revision applications (formerly called competing supplements or Type 3) to existing R01 grants that involve human subjects, allowing currently funded investigators to expand ongoing studies into the exercise and substance abuse intersection.
Is there a related or companion funding opportunity?
Yes. This R01 FOA runs alongside a companion FOA with the same scientific scope that uses the R03 mechanism: RFA-DA-09-014, which is generally intended for smaller, more limited projects.
How much funding was NIDA planning to commit?
NIDA planned to commit a total of about $4,000,000 in fiscal year 2009 across this R01 FOA and the companion R03 FOA combined.
How many awards were anticipated?
The FOA anticipated approximately 8 to 12 total awards across the R01 and R03 opportunities combined.
What is the CFDA number for this program?
The program falls under CFDA 93.279 (Drug Abuse and Addiction Research Programs).
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching funds are not required.
Who is eligible to apply?
Eligibility is broad and includes many organizations and institution types, including:
- Public and private institutions of higher education
- Nonprofits (with or without 501(c)(3) status)
- Small businesses
- For-profit organizations (including those other than small businesses)
- State, county, and local governments
- Independent school districts
- Special district governments
- Public housing authorities/Indian housing authorities
- Tribal governments and organizations (including federally recognized tribes and other tribal entities)
Are specific institution categories explicitly included?
Yes. The eligibility language explicitly includes organizations such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, and entities in U.S. territories or possessions.
Are foreign (non-U.S.) entities eligible?
Yes. The eligibility language explicitly includes non-U.S. (foreign) entities.
When was the FOA posted and when did it close?
The announcement was posted on October 16, 2008. The application closing date was January 28, 2009.
Is this FOA still active?
No. The FOA was archived on February 28, 2009.
What kinds of teams are this opportunity designed for?
The opportunity is designed for research teams that can credibly link exercise science with addiction science, particularly teams studying brain systems and behaviors that overlap with substance use risk and recovery.
What makes an application a strong fit for this FOA based on the description provided?
Strong applications would go beyond describing general health benefits of exercise and instead make a clear, evidence-based case for how the specific physical activity intervention or mechanism relates to substance abuse-relevant outcomes such as drug reward, craving, stress responsivity, cognition, relapse vulnerability, prevention, or treatment engagement and outcomes.
What is the required connection between exercise and addiction for proposed studies?
Each application must clearly explain how exercise-related changes in brain function and/or behavior tie to substance abuse. This can be framed as improving understanding of drug abuse mechanisms, improving prevention or treatment approaches, and/or showing how findings could realistically translate into use with substance-using populations.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DA 09 013) also looked into and applied for these:
| Funding Opportunity |
|---|
| Interactions between Physical Activity and Drug Abuse (R03) Apply for RFA DA 09 014 Funding Number: RFA DA 09 014 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Basic and Preclinical Research on Complementary and Alternative Medicine (CAM) (R01) Apply for PA 09 010 Funding Number: PA 09 010 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Mouse Gene Development Initiative (R01) Apply for RFA DA 09 015 Funding Number: RFA DA 09 015 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medical Management of Older Patients with HIV/AIDS (R01) Apply for PA 09 017 Funding Number: PA 09 017 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| International Research Collaboration on Drug Abuse and Addiction Research (R01) Apply for PA 09 020 Funding Number: PA 09 020 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| International Research Collaboration on Drug Abuse and Addiction Research (R21) Apply for PA 09 021 Funding Number: PA 09 021 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| International Research Collaboration on Drug Abuse and Addiction Research (R03) Apply for PA 09 022 Funding Number: PA 09 022 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Central Nervous System Intersections of Drug Addiction, Chronic Pain and Analgesia (R21) Apply for RFA DA 09 018 Funding Number: RFA DA 09 018 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Secondary Data Analyses for Substance Abuse Research (R21/R33) Apply for RFA DA 09 020 Funding Number: RFA DA 09 020 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Brain Imaging Studies of Negative Reinforcement in Humans (R01) Apply for RFA DA 09 008 Funding Number: RFA DA 09 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Brain Imaging Studies of Negative Reinforcement in Humans (R21) Apply for RFA DA 09 009 Funding Number: RFA DA 09 009 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Instrument Development for Biomedical Applications (R21) Apply for RFA RR 09 001 Funding Number: RFA RR 09 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $125,000 |
| Erythropoiesis Stimulating Agents and Tumor Progression (R01) Apply for PA 09 023 Funding Number: PA 09 023 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Erythropoiesis Stimulating Agents and Tumor Progression (R21) Apply for PA 09 024 Funding Number: PA 09 024 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| National Cancer Institute Program Project (P01) Applications Apply for PAR 09 025 Funding Number: PAR 09 025 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Collaborative Research in Integrative Cancer Biology and the Tumor Microenvironment (U01) Apply for PAR 09 026 Funding Number: PAR 09 026 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Education Programs of Excellence in Scientifically Validated Behavioral Treatment (R25) Apply for RFA MH 09 110 Funding Number: RFA MH 09 110 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Shared Instrumentation Grant Program (S10) Apply for PAR 09 028 Funding Number: PAR 09 028 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Mutant Mouse Regional Resource Centers (Limited Competition U42) Apply for RFA RR 09 003 Funding Number: RFA RR 09 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mutant Mouse Regional Resource Centers (U42) Apply for RFA RR 09 002 Funding Number: RFA RR 09 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
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