Opportunity Information: Apply for PAR 08 117
Apply for PAR 08 117
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Interdisciplinary Research on Oral Manifestations of HIV/AIDS in Vulnerable Populations (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
- This funding opportunity was created on Dec 2, 2008 and posted on Dec 2, 2008.
- Applicants must submit their applications by Aug 13, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,600,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The NIH funding opportunity PAR 08-117, titled "Interdisciplinary Research on Oral Manifestations of HIV/AIDS in Vulnerable Populations (P01)," is designed to support large, highly coordinated research programs focused on understanding and reducing oral health complications linked to HIV/AIDS-related immunosuppression. The central aim is to move the field forward through interdisciplinary, team-based science that tackles major gaps in what is known about how oral complications of HIV develop, how common they are in different groups, how they might be prevented, and how they can be better managed. A strong emphasis is placed on research that benefits vulnerable populations, including children and adolescents, and that addresses the disproportionate impact of HIV-related oral disease burdens in racial and ethnic minority communities.
The opportunity specifically expects applicants to propose an integrated Program Project Grant (P01), meaning the application should be built around multiple interrelated projects that are scientifically linked and mutually reinforcing rather than a collection of separate studies. These projects are expected to be synergistic, sharing ideas, methods, and resources in a way that produces a combined impact greater than what each project could accomplish alone. The intent is to generate a comprehensive understanding of oral manifestations and complications of HIV disease across the full spectrum of key issues: epidemiology (who is affected and under what conditions), prevention (what strategies can reduce incidence or severity), and pathogenesis (the biological mechanisms that drive disease development and progression).
A defining feature of this FOA is its push for cutting-edge tools and emerging technologies. Applicants are encouraged to incorporate modern, high-impact approaches such as genomics and proteomics to identify host and viral factors linked to oral disease susceptibility or progression, as well as molecular imaging and other advanced technologies that can clarify disease processes in vivo or at high resolution. The expectation is that these methods will be used strategically to answer important biological and clinical questions, not simply added as technical add-ons. Overall, the program is meant to accelerate discovery by combining clinical insight, basic science, translational research, and modern technology within a single coordinated structure.
In addition to the research objectives, the FOA places value on building the workforce in oral AIDS research. Applicants are expected to create meaningful interdisciplinary career development opportunities for investigators who are new to the oral AIDS field. In practice, this signals that strong proposals will likely demonstrate mentoring, cross-training, and collaborative environments that help newer researchers gain expertise across disciplines such as oral medicine, infectious diseases, immunology, microbiology, epidemiology, and biostatistics, along with exposure to advanced "omics" and imaging platforms.
Administratively, this is a discretionary grant opportunity offered by the National Institutes of Health under the activity category of health research, and it uses the NIH P01 mechanism (Program Project). It is associated with CFDA number 93.121, Oral Diseases and Disorders Research. There is no cost-sharing or matching requirement listed. The opportunity was posted on December 2, 2008, with an original and current closing date of August 13, 2010, and an archive date of September 13, 2010. The estimated total funding amount shown is $1,600,000, which reflects the scale typical of a coordinated multi-project program rather than a single investigator-initiated study.
Eligibility is broad and includes many organization types that commonly apply for NIH funding. Eligible applicants include public and private institutions of higher education, public/state-controlled institutions of higher education, state governments, federally recognized Native American tribal governments, Native American tribal organizations (including those not federally recognized), nonprofit organizations (both with and without 501(c)(3) status), for-profit organizations (other than small businesses), and small businesses. The FOA also notes inclusion of institutions serving historically underrepresented populations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and related eligible entities.
The full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-08-117.html, and support contacts were provided through the NIH Office of Extramural Research (OER) for access or linking issues.
FAQs: NIH PAR-08-117 - Interdisciplinary Research on Oral Manifestations of HIV/AIDS in Vulnerable Populations (P01)
1) What is the funding opportunity PAR-08-117?
PAR-08-117 is an NIH funding opportunity titled "Interdisciplinary Research on Oral Manifestations of HIV/AIDS in Vulnerable Populations (P01)." It supports large, highly coordinated research programs designed to improve understanding and reduction of oral health complications linked to HIV/AIDS-related immunosuppression.
2) What is the main purpose of this program?
The main purpose is to move the field forward through interdisciplinary, team-based science that addresses major gaps in knowledge about how oral complications of HIV develop, how common they are across groups, how they might be prevented, and how they can be better managed, with a strong focus on vulnerable populations.
3) What kinds of oral health issues is the FOA concerned with?
The FOA focuses on oral manifestations and complications associated with HIV disease and HIV/AIDS-related immunosuppression, particularly issues that contribute to disproportionate oral disease burdens in vulnerable and underserved groups.
4) Which populations are emphasized as priorities in this opportunity?
The opportunity emphasizes research that benefits vulnerable populations, including children and adolescents, and that addresses disproportionate impacts in racial and ethnic minority communities.
5) What grant mechanism does this opportunity use?
This opportunity uses the NIH P01 mechanism, also known as a Program Project Grant. The FOA specifically expects an integrated, coordinated program composed of multiple interrelated projects.
6) What does it mean that the application must be an "integrated Program Project (P01)"?
It means the application should include multiple projects that are scientifically linked and mutually reinforcing, rather than a set of separate, unrelated studies. The projects are expected to share ideas, methods, and resources in ways that create synergy and produce a combined impact greater than any single project could achieve alone.
7) What research areas should the program cover?
The FOA describes a comprehensive scope across key issues affecting oral complications in HIV, including epidemiology (who is affected and under what conditions), prevention (strategies that reduce incidence or severity), and pathogenesis (biological mechanisms driving development and progression).
8) Is the FOA focused on basic science, clinical research, or translational research?
It is designed to accelerate discovery by combining clinical insight, basic science, translational research, and modern technology within a single coordinated structure.
9) What is meant by "interdisciplinary, team-based science" in this FOA?
Interdisciplinary, team-based science refers to coordinated collaboration across multiple disciplines to address complex research gaps related to oral manifestations of HIV/AIDS. The FOA points to cross-disciplinary involvement that can include oral medicine, infectious diseases, immunology, microbiology, epidemiology, biostatistics, and advanced technology platforms.
10) Are applicants encouraged to use advanced technologies?
Yes. A defining feature of the FOA is its emphasis on cutting-edge tools and emerging technologies, and it encourages applicants to incorporate modern approaches to answer important biological and clinical questions.
11) What examples of cutting-edge tools or emerging technologies are mentioned?
The FOA specifically mentions genomics and proteomics to identify host and viral factors related to susceptibility or progression, and molecular imaging and other advanced technologies that can clarify disease processes in vivo or at high resolution.
12) Does the FOA expect advanced methods to be central to the science?
Yes. The FOA indicates these methods should be used strategically to address key questions, not included merely as technical add-ons.
13) Does this opportunity include career development expectations?
Yes. The FOA places value on building the workforce in oral AIDS research by expecting meaningful interdisciplinary career development opportunities for investigators new to the oral AIDS field.
14) What kinds of career development activities are implied?
The FOA signals that strong proposals will likely include mentoring, cross-training, and a collaborative environment that helps newer researchers gain expertise across relevant disciplines and gain exposure to advanced "omics" and imaging platforms.
15) What agency is offering this grant opportunity?
This is a discretionary grant opportunity offered by the National Institutes of Health (NIH).
16) What is the CFDA number associated with this opportunity?
The FOA is associated with CFDA number 93.121, Oral Diseases and Disorders Research.
17) Is there a cost-sharing or matching requirement?
No cost-sharing or matching requirement is listed for this opportunity.
18) What is the estimated total funding amount shown for the opportunity?
The estimated total funding amount shown is $1,600,000, reflecting the scale typical of a coordinated multi-project program rather than a single investigator-initiated study.
19) When was the opportunity posted?
The opportunity was posted on December 2, 2008.
20) What are the closing date and archive date for this opportunity?
The original and current closing date is August 13, 2010. The archive date is September 13, 2010.
21) What types of organizations are eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education; public/state-controlled institutions of higher education; state governments; federally recognized Native American tribal governments; Native American tribal organizations (including those not federally recognized); nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses); and small businesses.
22) Are institutions serving historically underrepresented populations included in the eligibility discussion?
Yes. The FOA notes inclusion of institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and related eligible entities.
23) Where can the full announcement be found?
The full announcement is available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-08-117.html.
24) Who is listed as a support contact for access or linking issues?
Support contacts were provided through the NIH Office of Extramural Research (OER) for access or linking issues.
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| NINDS Cooperative Program in Translational Research Single Component Research Projects (U01) Apply for PAR 08 233 Funding Number: PAR 08 233 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Cooperative Program in Translational Research Multi Component Research Projects (U54) Apply for PAR 08 234 Funding Number: PAR 08 234 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Cooperative Program in Translational Research Resource Centers (U24) Apply for PAR 08 236 Funding Number: PAR 08 236 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Program for Extramural/Intramural Alcohol Research Collaborations (U01) Apply for PAR 08 005 Funding Number: PAR 08 005 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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