Opportunity Information: Apply for RFA DA 15 010

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Interventions for Youth who Misuse/Abuse Prescription Stimulant Medications in High School and/or College Attending Youth (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Jul 22, 2014 and posted on Jul 22, 2014.
  • Applicants must submit their applications by Nov 13, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • Eligible applicants include: City or township governments For profit organizations other than small businesses Special district governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education County governments Small businesses Independent school districts Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The grant opportunity titled "Interventions for Youth who Misuse/Abuse Prescription Stimulant Medications in High School and/or College Attending Youth (U01)" (Funding Opportunity Number RFA-DA-15-010) is a National Institutes of Health (NIH) funding announcement focused on building a practical evidence base for addressing the misuse of prescription stimulant medications (PSMs) among adolescents and young adults in school settings. The core purpose is to support controlled research studies that either test clear, predefined hypotheses or generate new hypotheses, as long as the work is grounded in rigorous intervention research. The goal is not simply to describe the problem, but to develop and evaluate interventions that can actually prevent misuse, reduce misuse, and limit diversion (the sharing, selling, or otherwise transferring prescribed stimulants to people they were not intended for) among high school students and/or college students.

This FOA uses the U01 cooperative agreement mechanism, which generally means NIH expects to have a more active partnership role than it would under a typical research project grant. While applicants still lead the science and implementation, a cooperative agreement often involves substantial NIH programmatic involvement in areas like study coordination, milestone monitoring, and shaping certain aspects of the research approach to ensure the project aligns with the program goals. The funding instrument is categorized as discretionary and sits within the broad activity areas of education and health, under CFDA 93.279 (Drug Abuse and Addiction Research Programs), which historically aligns with NIH and NIDA-supported work on substance use and related prevention/treatment approaches.

The scientific scope is explicitly intervention-centered. Applicants are expected to propose controlled research that develops and tests the efficacy of prevention or reduction strategies for PSM misuse and diversion in youth populations who are in high school and/or attending college. In practice, this could include school-based, campus-based, healthcare-linked, digital, family-involved, peer-led, or multi-component interventions, as long as the design is controlled and the outcomes directly relate to misuse/diversion prevention or reduction. The announcement draws a clear boundary around what it will not support: animal studies and purely epidemiological research are considered unresponsive, meaning applications focused on basic animal work or studies limited to measuring prevalence, correlates, or trends without an intervention development and efficacy-testing component would not fit the intent of this solicitation.

Financially, the announcement lists an estimated total funding amount of $1,000,000 and an award ceiling of $1,000,000, with no cost sharing or matching requirement. This indicates applicants were not expected to bring mandatory matching funds, which lowers the barrier for organizations that may not have flexible funding to contribute. The FOA was posted on July 22, 2014, with an original and current closing date of November 13, 2014, and an archive date of December 14, 2014, meaning it was a time-limited competition and is now closed, but the details remain useful as a reference point for similar NIH/NIDA prevention-intervention solicitations.

Eligibility is broad and intentionally inclusive across many types of institutions that might realistically be positioned to run school- or college-attending youth intervention trials. Eligible applicants include state and local governments (including county governments, city or township governments, special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, public housing authorities/Indian housing authorities, Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized), nonprofit organizations both with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses. The opportunity also explicitly includes a wide range of designated institutions and community-based entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Notably, the FOA allows non-U.S. entities (foreign organizations and foreign institutions) to apply, permits non-U.S. components of U.S. organizations, and allows foreign components as defined by the NIH Grants Policy Statement, signaling that NIH was open to international perspectives and multi-site structures as long as the work remained responsive to the intervention goals and target populations.

For applicants seeking the complete official announcement and detailed NIH requirements, the FOA provided a link to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-15-010.html). For technical difficulties accessing the announcement or linking issues, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this grant?

The opportunity is titled "Interventions for Youth who Misuse/Abuse Prescription Stimulant Medications in High School and/or College Attending Youth (U01)" and the Funding Opportunity Number is RFA-DA-15-010.

Which agency is offering this funding opportunity?

This is a National Institutes of Health (NIH) funding announcement, aligned with NIH/NIDA work under CFDA 93.279 (Drug Abuse and Addiction Research Programs).

What is the main purpose of this FOA?

The purpose is to build a practical evidence base by supporting rigorous, controlled intervention research focused on preventing prescription stimulant medication (PSM) misuse, reducing misuse, and limiting diversion among adolescents and young adults in school settings (high school and/or college).

What problem area does the FOA focus on?

It focuses on the misuse/abuse of prescription stimulant medications by high school students and/or college-attending youth, including diversion (sharing, selling, or otherwise transferring prescribed stimulants to people they were not intended for).

What types of projects are responsive to this FOA?

Projects are expected to propose controlled research studies that develop and test the efficacy of interventions aimed at preventing or reducing PSM misuse and diversion in the target youth populations. Studies may test clear, predefined hypotheses or generate new hypotheses, as long as the work is grounded in rigorous intervention research.

Does the FOA support research that only describes the problem (for example, prevalence studies)?

No. The announcement emphasizes that the goal is not simply to describe the problem. Applications that are purely epidemiological (limited to measuring prevalence, correlates, or trends without an intervention development and efficacy-testing component) are considered unresponsive.

Are animal studies allowed under this FOA?

No. Animal studies are explicitly described as unresponsive to the announcement.

What is meant by "controlled research" in this announcement?

The FOA calls for controlled research designs to develop and test interventions. The provided information does not define a specific control type, but the expectation is that the intervention evaluation is conducted using a controlled approach rather than an uncontrolled or purely observational design.

What settings can the intervention focus on?

The focus is on school settings involving high school and/or college-attending youth. The FOA notes that interventions could be school-based, campus-based, healthcare-linked, digital, family-involved, peer-led, or multi-component, as long as the design is controlled and outcomes directly relate to misuse/diversion prevention or reduction.

Who is the target population?

The target population is adolescents and young adults in high school and/or youth attending college who misuse/abuse prescription stimulant medications, with emphasis on prevention, reduction, and diversion-limiting strategies.

What funding mechanism is used (and what does it imply)?

The FOA uses the U01 cooperative agreement mechanism. This typically implies a more active NIH partnership role than a standard research project grant, with substantial NIH programmatic involvement (for example, study coordination, milestone monitoring, and shaping aspects of the research approach to ensure alignment with program goals), while applicants still lead the science and implementation.

Is this a discretionary grant?

Yes. The funding instrument is categorized as discretionary.

What are the activity areas for this grant opportunity?

The opportunity sits within the broad activity areas of education and health.

What is the CFDA number associated with this opportunity?

The CFDA is 93.279, labeled as Drug Abuse and Addiction Research Programs.

How much total funding was estimated for this FOA?

The announcement lists an estimated total funding amount of $1,000,000.

What is the award ceiling?

The award ceiling is listed as $1,000,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

When was the FOA posted and when did it close?

The FOA was posted on July 22, 2014. The original and current closing date is November 13, 2014. The archive date is December 14, 2014.

Is this funding opportunity still open?

No. Based on the closing and archive dates provided, this was a time-limited competition and is now closed.

Who is eligible to apply?

Eligibility is broad and includes: state governments, local governments (including county, city or township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, public housing authorities/Indian housing authorities, Native American tribal governments (federally recognized), tribal organizations (including those not federally recognized), nonprofit organizations (with or without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. The FOA also includes faith-based or community-based organizations and eligible federal agencies.

Are minority-serving and special-designation institutions included in eligibility?

Yes. The announcement explicitly includes entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Can foreign (non-U.S.) organizations apply?

Yes. The FOA allows non-U.S. entities (foreign organizations and foreign institutions) to apply.

Are foreign components allowed for U.S. organizations?

Yes. The FOA permits non-U.S. components of U.S. organizations and allows foreign components as defined by the NIH Grants Policy Statement.

Where can applicants find the official FOA text?

The FOA pointed to the NIH Grants Guide page at: http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-15-010.html

Who should be contacted for technical problems accessing the announcement?

For technical difficulties accessing the announcement or linking issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What kinds of outcomes does the FOA prioritize?

The FOA prioritizes outcomes tied directly to preventing misuse, reducing misuse, and limiting diversion of prescription stimulant medications among high school and/or college-attending youth.

Can a project be hypothesis-generating, or does it have to test predefined hypotheses?

Either approach can be responsive. The FOA supports controlled research studies that test clear, predefined hypotheses or generate new hypotheses, as long as the research is grounded in rigorous intervention research.

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