Opportunity Information: Apply for PA 08 071
Apply for PA 08 071
- The National Institutes of Health in the education food and nutrition health sector is offering a public funding opportunity titled "Lab to Marketplace Tools for Brain and Behavioral Research (SBIR R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.361 Nursing Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jan 26, 2009 and posted on Jan 11, 2008.
- Applicants must submit their applications by Jan 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are not eligible to apply. Only United States small business concerns (SBCs) are eligible to submit SBIR applications. A small business concern is one that, at the time of award of Phase I and Phase II, meets all of the following criteria Organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor In the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there can be no more than 49 percent participation by business entities in the joint venture At least 51 percent owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States, or it must be a for profit business concern that is at least 51 owned and controlled by another for profit business concern that is at least 51 owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States (except in the case of a joint venture) Has, including its affiliates, not more than 500 employees and meets the other regulatory requirements found in 13 C.F.R. Part 121. Business concerns, other than investment companies licensed, or state development companies qualifying under the Small Business Investment Act of 1958, 15 U.S.C. 661, et seq., are affiliates of one another when either directly or indirectly, (a) one concern controls or has the power to control the other or (b) a third party/parties controls or has the power to control both. Control can be exercised through common ownership, common management, and contractual relationships. The term affiliates is defined in greater detail in 13 C.F.R. 121.3 2(a). The term number of employees is defined in 13 C.F.R. 121.3 2(t). Business concerns include, but are not limited to, any individual (sole proprietorship), partnership, corporation, joint venture, association, or cooperative. Further information may be obtained by contacting the Small Business Administration Size District Office at http://sba.gov/size.
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Opportunity Summary:
Lab to Marketplace Tools for Brain and Behavioral Research (SBIR R43/R44), funding opportunity number PA 08-071, is an NIH grant program built around the NIH Blueprint for Neuroscience Research, a cross-NIH effort designed to coordinate and strengthen research that advances understanding of the nervous system. Through this announcement, participating NIH Institutes and Centers invite Small Business Innovation Research (SBIR) applications that focus on moving practical technologies for brain and behavioral research out of academic labs or other non-small-business settings and into the commercial marketplace. The core idea is not to fund brand-new basic discoveries, but to help promising research tools make the jump from “works in one lab” to “robust, user-friendly, broadly adoptable product” that can be disseminated and supported commercially.
The opportunity specifically targets technologies used in brain and behavioral research that have already been developed to some degree and now need engineering, usability improvements, reliability testing, documentation, packaging, or other productization steps to become widely usable. NIH emphasizes that successful projects will often require close partnership between the original technology developers (frequently academic inventors) and the small business that will turn the tool into something that can be adopted by many end users. The FOA explicitly allows multiple PDs/PIs, which can make it easier to structure a true collaboration between the small business and the original inventor team while still meeting SBIR leadership rules.
Funding is offered under the SBIR grant mechanisms R43/R44, supporting Phase I, Phase II, and Fast Track applications. Phase I is intended to establish feasibility and de-risk the development path, and applicants may request up to $350,000 in total costs per year for up to 2 years. Phase II supports full research and development toward a commercializable product, with budgets up to $600,000 in total costs per year for up to 3 years. As with many NIH opportunities, awards depend on the availability of funds and the number and quality of applications received, rather than a guaranteed number of awards.
Eligibility is limited to United States small business concerns (SBCs). Foreign institutions are not eligible to apply. The SBC must be for-profit, have a place of business in the United States, and operate primarily in the United States or make a significant contribution to the US economy through taxes or the use of American products, materials, or labor. The organization must meet standard SBIR size and ownership requirements, including being no more than 500 employees including affiliates, and generally being at least 51 percent owned and controlled by US citizens or permanent resident aliens (or, in some cases, by another qualifying for-profit business that meets those ownership and control requirements). The FOA references Small Business Administration regulations (including 13 C.F.R. Part 121) for definitions of size, affiliates, and control.
For project leadership, NIH invites qualified individuals to serve as PD/PI(s), and it notes that individuals from underrepresented racial and ethnic groups and individuals with disabilities are encouraged to apply. A key SBIR requirement is highlighted: at least one PD/PI must have primary employment with the small business (more than 50 percent) at the time of award and for the duration of the project. This matters for teams that include academic inventors, because it typically requires careful planning around roles, effort, and employment arrangements to remain compliant while still keeping the original developers meaningfully involved.
On submissions, a single small business may submit more than one application as long as each is scientifically distinct. Resubmissions are allowed, but they must include an introduction that addresses the prior peer review critique (the Summary Statement). Renewals are more limited: only NIH Phase II SBIR awardees may apply for a competing renewal, and the renewal must represent continued R and D building on the previously funded Phase II work. Phase II competing renewals are accepted according to participating Institute and Center requirements described in the SBIR Omnibus Solicitation program descriptions and research topics.
Administrative details in the listing reflect the historical posting: the FOA was posted January 11, 2008, with an original closing date of January 7, 2011, and it was archived February 7, 2011. The announcement sits within NIH’s broader portfolio of research areas across multiple CFDA numbers, reflecting that multiple Institutes and Centers can participate depending on the specific brain, behavior, or neuroscience-relevant tool and its alignment with their missions. The full archived announcement is available through NIH’s grants guide at the link provided in the source.
Frequently Asked Questions (FAQs)
What is the "Lab to Marketplace Tools for Brain and Behavioral Research (SBIR R43/R44)" opportunity?
This is an NIH Small Business Innovation Research (SBIR) funding opportunity focused on moving practical technologies for brain and behavioral research from academic labs (or other non-small-business settings) into the commercial marketplace. It is associated with the NIH Blueprint for Neuroscience Research, a cross-NIH effort to coordinate and strengthen neuroscience research.
What is the funding opportunity number for this announcement?
The funding opportunity number is PA 08-071.
What is the main purpose of this FOA?
The main purpose is to support productization and commercialization steps that help an already-developed brain or behavioral research tool become robust, user-friendly, broadly adoptable, and suitable for dissemination and commercial support. The emphasis is on translating a tool that "works in one lab" into a product that many end users can use reliably.
Is this program meant to fund brand-new basic research discoveries?
No. The program is described as not being aimed at funding brand-new basic discoveries. Instead, it targets promising technologies that already exist to some degree and need additional development to become widely usable products.
What kinds of projects or activities does NIH expect to be supported?
The announcement highlights later-stage development and productization work such as engineering, usability improvements, reliability testing, documentation, packaging, and other steps needed to make a technology broadly usable in brain and behavioral research settings.
What types of technologies does this opportunity target?
It specifically targets technologies used in brain and behavioral research that have already been developed to some extent and now require further work to be ready for widespread adoption and commercial dissemination.
Does NIH expect collaboration with the original technology developers?
Yes. The FOA emphasizes that successful projects will often require close partnership between the original technology developers (frequently academic inventors) and the small business that will convert the tool into a commercially supportable product.
Does the FOA allow multiple PDs/PIs?
Yes. The FOA explicitly allows multiple PDs/PIs, which can help structure collaborations between a small business and original inventor teams while still following SBIR leadership requirements.
What SBIR mechanisms are used for funding under this opportunity?
Funding is offered under the NIH SBIR mechanisms R43 and R44, supporting Phase I, Phase II, and Fast Track applications.
What is the goal of Phase I under this FOA?
Phase I is intended to establish feasibility and de-risk the development path for the technology.
What is the Phase I budget limit and project period described in the announcement?
Applicants may request up to $350,000 in total costs per year for up to 2 years for Phase I.
What is the goal of Phase II under this FOA?
Phase II supports full research and development toward a commercializable product.
What is the Phase II budget limit and project period described in the announcement?
Budgets may be up to $600,000 in total costs per year for up to 3 years for Phase II.
Are awards guaranteed, or do they depend on funds and application quality?
Awards are not guaranteed. The announcement indicates awards depend on the availability of funds and the number and quality of applications received.
Who is eligible to apply?
Eligibility is limited to United States small business concerns (SBCs) that meet standard SBIR eligibility requirements.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this opportunity.
What basic characteristics must the small business have to qualify?
The small business must be for-profit, have a place of business in the United States, and operate primarily in the United States or make a significant contribution to the US economy through taxes or the use of American products, materials, or labor.
Is there an employee size limit for eligibility?
Yes. The business must generally have no more than 500 employees, including affiliates, as described in the SBIR requirements referenced in the FOA.
What ownership and control requirements are described?
The FOA describes that the SBC must generally be at least 51 percent owned and controlled by US citizens or permanent resident aliens, or in some cases owned by another qualifying for-profit business that meets those ownership and control requirements.
What regulations define size, affiliates, and control for eligibility?
The FOA references Small Business Administration regulations, including 13 C.F.R. Part 121, for definitions related to size, affiliates, and control.
Who can serve as PD/PI on an application?
NIH invites qualified individuals to serve as PD/PI(s). The FOA also notes that individuals from underrepresented racial and ethnic groups and individuals with disabilities are encouraged to apply.
What is the SBIR primary employment requirement for the PD/PI?
At least one PD/PI must have primary employment with the small business (more than 50 percent) at the time of award and for the duration of the project.
Why does the PD/PI primary employment requirement matter for academic inventor collaborations?
The FOA notes this can require careful planning of roles, effort, and employment arrangements, particularly when academic inventors are involved, to remain compliant while still keeping original developers meaningfully engaged.
Can a single small business submit more than one application?
Yes. A single small business may submit more than one application as long as each application is scientifically distinct.
Are resubmissions allowed?
Yes. Resubmissions are allowed, but they must include an introduction that addresses the prior peer review critique (the Summary Statement).
Who can apply for renewals (competing renewals) under this FOA?
Only NIH Phase II SBIR awardees may apply for a competing renewal, and the renewal must represent continued research and development building on the previously funded Phase II work.
How are Phase II competing renewals handled?
The FOA states that Phase II competing renewals are accepted according to participating Institute and Center requirements described in the SBIR Omnibus Solicitation program descriptions and research topics.
When was this FOA posted, and what is its status?
The listing reflects that the FOA was posted on January 11, 2008, had an original closing date of January 7, 2011, and was archived on February 7, 2011.
Is this opportunity associated with multiple NIH Institutes and Centers?
Yes. The announcement indicates that participating NIH Institutes and Centers may be involved, and that alignment can depend on how a particular brain, behavior, or neuroscience-relevant tool fits with the missions of those Institutes and Centers.
Where can applicants find the full archived announcement?
The full archived announcement is available through NIH's grants guide at the link provided in the source listing.
Browse more opportunities from the same category: Education Food and Nutrition Health
Next opportunity: New Technologies for Transient Molecular Complex Characterization (SBIR R43/R44)
Previous opportunity: Competing Renewal Awards of SBIR Phase II Grants for Brain and Behavior Tools (R44)
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