Opportunity Information: Apply for RFA OD 12 001

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Lasker Clinical Research Scholars Program (Si2)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.140 Intramural Research Training Award.
  • This funding opportunity was created on Nov 18, 2011 and posted on Nov 18, 2011.
  • Applicants must submit their applications by Jan 24, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Applications will be submitted directly by the individual PI, not from an organization.
Apply for RFA OD 12 001

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Opportunity Summary:

The Lasker Clinical Research Scholars Program (Si2) is a National Institutes of Health (NIH) grant opportunity designed to create a clear, career-spanning bridge between NIH's intramural research environment and the broader extramural research community. The core idea is to recruit and develop outstanding clinical researchers by giving them a structured pathway that starts inside NIH with strong institutional support and then, for those who are successful, enables a transition to an external (extramural) research setting with continued NIH funding. In practice, it is meant to combine the advantages of intramural NIH resources and mentorship with the long-term flexibility of building a research program at an academic medical center or other external research institution.

The program is explicitly organized into two phases. In the first phase, selected Lasker Scholars receive an appointment as tenure-track investigators within the NIH Intramural Research Program (IRP). This initial appointment can last up to 5 to 7 years and is paired with an independent research budget, positioning the scholar to run an autonomous research program rather than functioning solely under a more senior investigator. This phase is intended to give scholars time, stability, and access to NIH infrastructure so they can establish their scientific direction, build a track record, and develop as independent investigators within the intramural setting.

The second phase is a continuation option for scholars who meet the program's expectations during the intramural period. Successful scholars become eligible to apply for up to 5 additional years of NIH support to conduct their research at an extramural research facility. This feature is what makes the program distinctive: it is not just an intramural appointment and not just an extramural award, but a deliberate pathway that can support a transition between the two worlds while maintaining research momentum. Alternatively, instead of moving to an external institution, a scholar may be considered to remain as an investigator within the intramural program, meaning the program can support either a transition outward or a continued intramural trajectory depending on the scholar's progress and fit.

Administratively, this opportunity is issued by the NIH under Funding Opportunity Number RFA-OD-12-001 and is categorized as a discretionary grant. The funding activity category is listed under education and health, and the associated CFDA number is 93.140 (Intramural Research Training Award). There is no cost sharing or matching requirement stated. A notable eligibility feature is that applications are submitted directly by the individual principal investigator (PI), rather than being submitted by an organization, and the listing notes "Others" as eligible applicants with further clarification referenced in the full announcement.

Key dates in the archived posting show the opportunity was posted and created on November 18, 2011, with an original and current closing date of January 24, 2012, and an archive date of February 24, 2012. The full announcement was made available through an NIH Grants Guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-12-001.html). For access or technical issues related to the announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs) - Lasker Clinical Research Scholars Program (Si2)

What is the Lasker Clinical Research Scholars Program (Si2)?

The Lasker Clinical Research Scholars Program (Si2) is a National Institutes of Health (NIH) grant opportunity intended to create a career-spanning bridge between NIH's intramural research environment and the broader extramural research community. It is designed to recruit and develop outstanding clinical researchers through a structured pathway that begins within NIH and can later transition to an external research setting with continued NIH support.

What is the main goal of this program?

The core goal is to develop outstanding clinical researchers by combining the advantages of NIH intramural resources and mentorship with the long-term flexibility of building a research program at an academic medical center or other external research institution. The structure is meant to maintain research momentum across a potential move from intramural to extramural settings.

How is the program structured?

The program is explicitly organized into two phases: an initial intramural phase as an NIH Intramural Research Program (IRP) tenure-track investigator, followed by an optional second phase that may provide up to five additional years of NIH support for research conducted at an extramural research facility (or, alternatively, consideration to remain as an investigator within the intramural program).

What happens in Phase 1 (the intramural phase)?

In Phase 1, selected Lasker Scholars receive an appointment as tenure-track investigators within the NIH Intramural Research Program (IRP). This appointment can last up to 5 to 7 years. Scholars receive an independent research budget and are positioned to run an autonomous research program, with time and access to NIH infrastructure to establish scientific direction, build a track record, and develop as independent investigators.

How long can the intramural Phase 1 appointment last?

The initial tenure-track appointment within the NIH Intramural Research Program may last up to 5 to 7 years.

Does Phase 1 provide independent research support?

Yes. Phase 1 includes an independent research budget and is intended to support an autonomous research program rather than placing the scholar solely under a more senior investigator.

What happens in Phase 2 (the continuation/extramural option)?

Phase 2 is a continuation option for scholars who meet the program's expectations during the intramural period. Successful scholars become eligible to apply for up to 5 additional years of NIH support to conduct their research at an extramural research facility. This is intended to enable a transition to the extramural research community while maintaining continuity in funding and research progress.

How long can Phase 2 funding last?

Phase 2 may provide up to 5 additional years of NIH support for research conducted at an extramural research facility (for scholars who are successful during the intramural phase and who apply for the continuation option).

Is moving to an extramural institution required?

No. The description indicates that, alternatively, instead of moving to an external institution, a scholar may be considered to remain as an investigator within the intramural program. The program can support either a transition outward or a continued intramural trajectory depending on the scholar's progress and fit.

Who issues this funding opportunity?

This opportunity is issued by the National Institutes of Health (NIH).

What is the Funding Opportunity Number (FON) for this program?

The Funding Opportunity Number is RFA-OD-12-001.

What type of funding is this categorized as?

It is categorized as a discretionary grant.

What funding activity categories are associated with this opportunity?

The funding activity category is listed under education and health.

What CFDA number is associated with this program?

The associated CFDA number is 93.140, labeled as the Intramural Research Training Award.

Is there a cost sharing or matching requirement?

No cost sharing or matching requirement is stated in the information provided.

Who submits the application: the institution or the individual?

Applications are submitted directly by the individual principal investigator (PI), rather than being submitted by an organization.

Who is eligible to apply?

The listing notes "Others" as eligible applicants, with further clarification referenced in the full announcement. The information provided does not include additional eligibility details beyond that note.

Where can the full announcement be found?

The full announcement is available through the NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-12-001.html

When was this opportunity posted and created?

The archived posting shows it was posted and created on November 18, 2011.

What were the closing dates for applications?

The original and current closing date shown in the archived posting is January 24, 2012.

Is this opportunity archived?

Yes. The archive date listed is February 24, 2012.

Who should be contacted for access or technical issues related to the announcement?

For access or technical issues related to the announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What makes this program distinctive compared with typical intramural or extramural support?

The distinctive feature described is the deliberate two-phase pathway: it starts with an NIH intramural tenure-track investigator appointment with independent support, and for successful scholars it can extend into an extramural setting with continued NIH funding for up to five additional years, helping maintain research momentum across the transition.

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