Opportunity Information: Apply for PA 12 022
Apply for PA 12 022
- The National Institutes of Health in the education food and nutrition health sector is offering a public funding opportunity titled "Practical Interventions to Improve Medication Adherence in Primary Care (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.361 Nursing Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.866 Aging Research 93.867 Vision Research.
- This funding opportunity was created on Nov 18, 2011 and posted on Nov 18, 2011.
- Applicants must submit their applications by Jan 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education Private institutions of higher education State governments Special district governments Independent school districts Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses County governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
Practical Interventions to Improve Medication Adherence in Primary Care (R01) (Funding Opportunity Number PA-12-022) is an NIH research grant opportunity focused on developing and testing real-world, workable interventions that help patients take medications as prescribed in primary care settings. The core aim is practical impact: proposals are expected to move beyond documenting that nonadherence exists and instead design, implement, and evaluate approaches that can be used routinely in everyday clinical workflows to improve adherence and, ultimately, health outcomes. The mechanism is the NIH Research Project Grant (R01), meaning applicants are generally expected to propose a well-justified research plan with clear hypotheses or objectives, a rigorous evaluation strategy, and a pathway to generate generalizable knowledge about what works, for whom, and under what conditions.
The announcement is issued through the NIH Adherence Network led by the Office of Behavioral and Social Sciences Research (OBSSR), with multiple NIH Institutes and Centers participating. These include the National Cancer Institute (NCI), National Eye Institute (NEI), National Heart, Lung, and Blood Institute (NHLBI), National Institute on Aging (NIA), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute of Mental Health (NIMH), National Institute of Nursing Research (NINR), and the National Center for Complementary and Alternative Medicine (NCCAM, now known as NCCIH). The broad mix of participating Institutes signals that NIH is interested in adherence interventions that apply across many conditions relevant to primary care, such as cardiovascular disease, diabetes, cancer-related care, mental health treatment, aging-related chronic disease management, vision conditions, and others where medication adherence is a major determinant of patient outcomes.
From an applicant standpoint, the eligible organization types are wide-ranging. Universities and colleges (public and private), state and local governments, tribal governments and tribal organizations, regional organizations, independent school districts, public housing authorities/Indian housing authorities, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations (including those other than small businesses) are all listed as eligible. The FOA explicitly includes several institution categories often emphasized in federal funding, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations, as well as U.S. territories or possessions. At the same time, there are clear geographic restrictions: non-U.S. (foreign) institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed under this announcement.
Administratively, this is a discretionary grant opportunity with no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of the award. The opportunity was posted and created on November 18, 2011, with an original and current closing date of January 7, 2014, and it was archived on February 7, 2014. The CFDA program numbers associated with the FOA reflect the participating Institutes and the cross-cutting nature of the topic, spanning areas such as mental health research, nursing research, cancer control, cardiovascular research, diabetes/digestive/kidney research, aging research, vision research, communication disorders, and complementary and integrative health.
In practical terms, a competitive application under this FOA would be expected to propose an intervention that is feasible in primary care and directly targets medication adherence barriers that commonly occur in real life. These barriers can include forgetfulness, side effects, complex regimens, limited health literacy, cost-related nonadherence, inadequate follow-up, behavioral health comorbidities, or system-level challenges like poor care coordination and weak medication reconciliation. Because the FOA emphasizes "practical interventions," reviewers would typically look for strategies that are implementable and scalable within primary care environments, potentially leveraging care teams, health information technology, patient education supports, behavioral approaches, and workflow changes that fit routine practice rather than highly specialized research-only conditions.
The sponsoring NIH offices also provide basic access and support details. The full announcement is available through NIH's grants website (link provided in the source), and applicants who have trouble accessing the announcement or encounter technical linking problems are directed to contact the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
1) What is the goal of this funding opportunity (PA-12-022)?
This NIH Funding Opportunity Announcement (FOA) supports research to develop and test practical, real-world interventions that improve medication adherence in primary care settings. The emphasis is on approaches that can be used routinely in everyday clinical workflows and that ultimately improve health outcomes.
2) What does NIH mean by "practical interventions" in this FOA?
"Practical" signals that proposed interventions should be workable in routine primary care, not limited to highly controlled research-only conditions. Projects are expected to go beyond documenting that nonadherence exists and instead design, implement, and evaluate strategies that can be implemented and scaled within typical primary care environments.
3) What type of grant mechanism is used for this opportunity?
The mechanism is the NIH Research Project Grant (R01). Applicants are generally expected to propose a well-justified research plan with clear hypotheses or objectives, a rigorous evaluation strategy, and a pathway to generate generalizable knowledge about what works, for whom, and under what conditions.
4) What setting is the FOA focused on?
The FOA is focused on primary care settings. Proposed interventions should fit into real-world primary care workflows and be feasible for routine use.
5) What kinds of problems or barriers to adherence can an intervention address?
The FOA highlights real-life barriers that commonly drive nonadherence, such as forgetfulness, side effects, complex medication regimens, limited health literacy, cost-related nonadherence, inadequate follow-up, behavioral health comorbidities, and system-level issues like poor care coordination or weak medication reconciliation.
6) What types of intervention strategies are implied as relevant for this FOA?
Interventions may leverage primary care teams, health information technology, patient education supports, behavioral approaches, and workflow changes. The key expectation is that the strategy can be implemented and sustained in routine practice rather than requiring specialized research infrastructure.
7) Is the FOA limited to any single disease area?
No. The participating NIH Institutes and Centers span many conditions relevant to primary care, signaling interest in adherence interventions across a wide range of clinical areas, including cardiovascular disease, diabetes, cancer-related care, mental health treatment, aging-related chronic disease management, vision conditions, communication disorders, and complementary/integrative health-related contexts where adherence affects outcomes.
8) Who is leading and participating in this NIH effort?
The announcement is issued through the NIH Adherence Network led by the Office of Behavioral and Social Sciences Research (OBSSR). Participating NIH Institutes and Centers include NCI, NEI, NHLBI, NIA, NIDCD, NIDDK, NIMH, NINR, and NCCAM (now known as NCCIH).
9) What organization types are eligible to apply?
Eligible organizations are broad and include universities and colleges (public and private), state and local governments, tribal governments and tribal organizations, regional organizations, independent school districts, public housing authorities/Indian housing authorities, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, and for-profit organizations (including those other than small businesses).
10) Are minority-serving institutions and community-based organizations included as eligible applicants?
Yes. The FOA explicitly includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based organizations, and community-based organizations. U.S. territories or possessions are also included.
11) Are foreign (non-U.S.) institutions eligible to apply?
No. Non-U.S. (foreign) institutions are not eligible to apply under this announcement.
12) Can a U.S. organization include a non-U.S. component or foreign component in the project?
No. Non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed under this FOA.
13) Is cost sharing or matching required?
No. This is a discretionary grant opportunity and the FOA states there is no cost sharing or matching requirement.
14) What are the key dates for this opportunity?
The opportunity was posted and created on November 18, 2011. The original and current closing date listed is January 7, 2014. The FOA was archived on February 7, 2014.
15) Is this opportunity still open?
Based on the information provided, the FOA has a closing date of January 7, 2014 and was archived on February 7, 2014, indicating it is not currently active.
16) What does NIH appear to expect in a competitive application?
The FOA emphasizes practical impact and real-world use in primary care. A competitive application would be expected to propose an intervention that is feasible in primary care, directly targets common adherence barriers, includes a rigorous implementation and evaluation approach, and produces generalizable knowledge about what works, for whom, and under what conditions.
17) What does the FOA suggest about scalability and routine use?
Because the FOA emphasizes implementable and scalable approaches, reviewers would typically look for interventions that fit routine primary care environments, integrate into everyday workflows, and can be used beyond a single study site or specialized setting.
18) Where can applicants find the full FOA announcement?
The full announcement is available through NIH's grants website (as referenced in the source information).
19) Who should be contacted for technical problems accessing the announcement link?
Applicants with trouble accessing the announcement or experiencing technical linking problems are directed to contact the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
20) What are CFDA program numbers, and what do they indicate here?
The CFDA program numbers associated with the FOA reflect the multiple participating NIH Institutes and the cross-cutting nature of the topic, spanning areas such as mental health research, nursing research, cancer control, cardiovascular research, diabetes/digestive/kidney research, aging research, vision research, communication disorders, and complementary and integrative health.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 12 022) also looked into and applied for these:
| Funding Opportunity |
|---|
| Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition (R21) Apply for PA 12 139 Funding Number: PA 12 139 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $200,000 |
| Native American Research Centers for Health (NARCH) Apply for PAR 12 182 Funding Number: PAR 12 182 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R01) Apply for PAR 13 055 Funding Number: PAR 13 055 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Native American Research Centers for Health (NARCH) (S06) Apply for PAR 13 239 Funding Number: PAR 13 239 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Person Centered Outcomes Research Resource (U2C) Apply for RFA CA 13 008 Funding Number: RFA CA 13 008 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| UNMC Public Health Project NOI not a request for proposals Apply for P13AC00963 Funding Number: P13AC00963 Agency: National Park Service Category: Education Food and Nutrition Health Funding Amount: $100,000 |
| Systemic Amyloidosis Basic, Translational, and Clinical Research (R01) Apply for PA 13 286 Funding Number: PA 13 286 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Health Promotion Among Racial and Ethnic Minority Males (R01) Apply for PA 13 328 Funding Number: PA 13 328 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01) Apply for PAR 13 375 Funding Number: PAR 13 375 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Administrative Supplements to NIH Awards for Validation Studies of Analytical Methods for Natural Products (Admin Supp) Apply for PA 13 381 Funding Number: PA 13 381 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $100,000 |
| Behavioral Interventions to Address Multiple Chronic Health Conditions in Primary Care (R01) Apply for PA 14 114 Funding Number: PA 14 114 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Multidisciplinary Studies of HIV and Viral Hepatitis Co Infection (R01) Apply for PAR 14 255 Funding Number: PAR 14 255 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Multidisciplinary Studies of HIV and Viral Hepatitis Co Infection (R21) Apply for PAR 14 254 Funding Number: PAR 14 254 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $275,000 |
| Long Term Outcomes of Bariatric Surgery Using Large Datasets (R01) Apply for PAR 14 262 Funding Number: PAR 14 262 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $500,000 |
| Advancing Interventions to Improve Medication Adherence (R01) Apply for PA 14 334 Funding Number: PA 14 334 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
| Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Centers (CSCPDPC CCs) (U01) Apply for RFA DK 14 027 Funding Number: RFA DK 14 027 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $270,000 |
| Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CSCPDPC CDMC) (U01) Apply for RFA DK 14 028 Funding Number: RFA DK 14 028 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $1,000,000 |
| Administrative Supplements for Common Basic Sociobehavioral Mechanisms and Processes that Facilitate or Impede Self Management of Chronic Conditions (Admin Supp) Apply for PA 15 122 Funding Number: PA 15 122 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: $100,000 |
| Limited Competition for Renewal Applications Collaborating Centers of Excellence in Regulatory Science and Innovation (U01) Apply for RFA FD 15 009 Funding Number: RFA FD 15 009 Agency: Food Drug Administration Category: Education Food and Nutrition Health Funding Amount: $250,000 |
| Neuroimaging in Obesity Research (R01) Apply for RFA DK 08 009 Funding Number: RFA DK 08 009 Agency: National Institutes of Health Category: Education Food and Nutrition Health Funding Amount: Case Dependent |
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