Opportunity Information: Apply for RFA AA 16 002

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition Consortia for HIV/AIDS and Alcohol Related Research Trials (CHAART) Administrative Resource Core (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Jul 8, 2015 and posted on Jul 8, 2015.
  • Applicants must submit their applications by Jan 15, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $7,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education.
Apply for RFA AA 16 002

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Opportunity Summary:

The Limited Competition Consortia for HIV/AIDS and Alcohol Related Research Trials (CHAART) Administrative Resource Core (U24) grant opportunity, Funding Opportunity Number RFA-AA-16-002, was a National Institutes of Health (NIH) cooperative agreement designed to fund an administrative coordinating core that supports a larger, linked set of research projects focused on the intersection of alcohol use and HIV/AIDS. Rather than funding stand-alone scientific studies, this U24 mechanism was aimed at strengthening the infrastructure needed to run, coordinate, and maximize the impact of companion U01 research projects operating within the CHAART consortia. In practical terms, the award was meant to provide the organizational backbone that helps multiple research teams work as a unified program, with shared processes, consistent oversight, and coordinated planning.

The scientific and public health focus of the FOA centered on advancing operations research and implementation research in contexts where alcohol use influences HIV-related outcomes. The announcement emphasized two connected aims. First, it sought to help the consortia continue developing broader, systems-level approaches for monitoring complex patterns of HIV- and alcohol-related morbidity and mortality. That framing points to the need to understand how alcohol use interacts with medical care, adherence, co-morbid conditions, social and structural factors, and health systems performance, and to track how these interacting factors contribute to illness and death over time. Second, it aimed to support efforts to intervene in order to reduce the impact of alcohol on HIV disease progression and on HIV transmission. This reflects a recognition that alcohol can affect HIV outcomes through multiple pathways, including behavior (such as sexual risk), treatment engagement and adherence, and biological or clinical processes that influence disease progression.

The FOA explicitly aligned the initiative with the Trans-NIH Plan for HIV-Related Research, signaling that the work was expected to contribute to broader federal research priorities in HIV. The CHAART initiative, as reflected in the FOA language, was intended to support coordinated research that could produce actionable findings relevant to real-world practice and public health implementation, particularly where alcohol use complicates prevention, care engagement, and long-term HIV management.

From an administrative and programmatic standpoint, the purpose of the U24 was to solicit applications that would provide administrative support to the companion U01 projects. Because this was a cooperative agreement, NIH would have substantial involvement in the conduct of the program, which typically means more active federal participation in coordinating activities, monitoring progress, and ensuring that the collaborative goals of the consortia are met. In general, an Administrative Resource Core under a program like this would be expected to handle cross-project coordination, meeting logistics and communications, tracking milestones and deliverables, facilitating common policies and procedures across sites, and supporting consistent reporting and collaboration among investigators. While the FOA summary does not list all required components, the intent is clear: the U24 award functions as shared infrastructure that makes it easier for the U01 projects to operate as a coherent consortium rather than as isolated studies.

Eligibility was limited to higher education institutions, including private institutions of higher education and public or state-controlled institutions of higher education. The opportunity did not require cost sharing or matching. NIH anticipated making about four awards under this FOA. The estimated total funding amount was approximately $7,000,000, and the award ceiling listed was $200,000 (which typically refers to a maximum per-award amount, often per year, depending on the FOA structure). The opportunity fell under the health activity category and was associated with CFDA number 93.273, Alcohol Research Programs.

Key dates show that the FOA was posted on July 8, 2015, with an original and current closing date of January 15, 2016, and an archive date of February 15, 2016, meaning it is no longer accepting applications. The administering agency was NIH, and additional details were available through the NIH grants guide page associated with the announcement. For technical issues accessing the announcement, applicants were directed to the NIH Office of Extramural Research (OER) webmaster contact.

FAQs: Limited Competition Consortia for HIV/AIDS and Alcohol Related Research Trials (CHAART) Administrative Resource Core (U24) - RFA-AA-16-002

What is the CHAART Administrative Resource Core (U24) grant opportunity?

This opportunity (Funding Opportunity Number RFA-AA-16-002) was an NIH cooperative agreement (U24) intended to fund an administrative coordinating core for the CHAART consortia. Its main purpose was to provide shared infrastructure and coordination for a linked set of companion U01 research projects focused on the intersection of alcohol use and HIV/AIDS.

Is this grant meant to fund stand-alone scientific research studies?

No. The U24 mechanism described here was not aimed at funding a stand-alone scientific study. It was aimed at strengthening the infrastructure needed to run, coordinate, and maximize the impact of the companion U01 research projects operating within the CHAART consortia.

What does "Administrative Resource Core" mean in this FOA?

In this FOA, an Administrative Resource Core refers to a centralized coordinating function that supports multiple linked projects. It serves as the organizational backbone for the consortia by helping research teams operate as a unified program with shared processes, consistent oversight, coordinated planning, and aligned reporting.

What types of activities would the U24 Administrative Resource Core typically support?

Based on the FOA description, the core would typically support cross-project coordination, meeting logistics and communications, tracking milestones and deliverables, facilitating common policies and procedures across sites, and supporting consistent reporting and collaboration among investigators.

What is the scientific and public health focus of this opportunity?

The FOA focused on advancing operations research and implementation research in contexts where alcohol use influences HIV-related outcomes. The emphasis was on producing actionable findings relevant to real-world practice and public health implementation, especially where alcohol use complicates prevention, care engagement, and long-term HIV management.

What were the two connected aims highlighted in the FOA?

The FOA emphasized two related aims: (1) helping the consortia develop broader, systems-level approaches for monitoring complex patterns of HIV- and alcohol-related morbidity and mortality, and (2) supporting efforts to intervene to reduce the impact of alcohol on HIV disease progression and on HIV transmission.

What does "systems-level approaches" refer to in this context?

It refers to approaches that can monitor and account for complex, interacting factors affecting health outcomes over time. The FOA framing points to understanding how alcohol use interacts with medical care, treatment adherence, co-morbid conditions, social and structural factors, and health system performance, and how these relationships contribute to illness and death.

How does alcohol use relate to HIV outcomes according to the FOA summary?

The FOA recognized multiple pathways through which alcohol can affect HIV outcomes, including behavioral pathways (such as sexual risk), engagement in care and treatment adherence, and biological or clinical processes that influence HIV disease progression.

What is the relationship between the U24 award and the companion U01 projects?

The U24 was designed to provide administrative support to the companion U01 projects within the CHAART consortia. In practical terms, it was intended to improve coordination, oversight, and shared operations so the U01 projects could function as a coherent consortium rather than as isolated studies.

What does it mean that this is a "cooperative agreement"?

A cooperative agreement indicates that NIH would have substantial involvement in the conduct of the program. As described in the summary, this typically means more active federal participation in coordinating activities, monitoring progress, and helping ensure the collaborative goals of the consortia are met.

Which agency administered this funding opportunity?

The administering agency was the National Institutes of Health (NIH).

Who was eligible to apply?

Eligibility was limited to higher education institutions, including private institutions of higher education and public or state-controlled institutions of higher education.

Was cost sharing or matching required?

No. The opportunity did not require cost sharing or matching.

How many awards did NIH expect to make?

NIH anticipated making about four awards under this FOA.

What was the estimated total funding amount for this FOA?

The estimated total funding amount was approximately $7,000,000.

What was the award ceiling listed for this opportunity?

The award ceiling listed was $200,000. The summary notes this typically refers to a maximum per-award amount, often per year, depending on the FOA structure.

What is the CFDA number associated with this opportunity?

The FOA was associated with CFDA number 93.273, Alcohol Research Programs.

What activity category did this opportunity fall under?

The opportunity fell under the health activity category.

When was the FOA posted?

The FOA was posted on July 8, 2015.

What was the application due date?

The original and current closing date listed was January 15, 2016.

Is this funding opportunity still open?

No. The archive date was February 15, 2016, and the FOA is no longer accepting applications.

Did the FOA align with any broader federal HIV research priorities?

Yes. The FOA explicitly aligned the initiative with the Trans-NIH Plan for HIV-Related Research, indicating that the work was expected to contribute to broader federal research priorities in HIV.

Where could applicants find the official announcement details?

Additional details were available through the NIH grants guide page associated with the announcement.

Who could applicants contact for technical issues accessing the announcement?

For technical issues accessing the announcement, applicants were directed to the NIH Office of Extramural Research (OER) webmaster contact.

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