Opportunity Information: Apply for RFA DK 11 501
Apply for RFA DK 11 501
- The National Institutes of Health in the environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.142 NIEHS Hazardous Waste Worker Health and Safety Training 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Apr 29, 2011 and posted on Apr 29, 2011.
- Applicants must submit their applications by Jun 30, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $70,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $16,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following As this FOA is a limited competition opportunity, only the institution that is the principal employer of the Principal Investigator of the TEDDY Data Coordinating Center is eligible to apply in response to this FOA. Required Registrations Applicant organizations must complete the following registrations as described in the SF 424 (R and R) Application Guide to be eligible to apply for or receive an award. Applicants must have a valid Dun and Bradstreet Universal Numbering System (DUNS) number in order to begin each of the following registrations. Central Contractor Registration (CCR) must maintain an active registration, to be renewed at least annually Grants.gov eRA Commons All Program Directors/Principal Investigators (PD/PIs) must also work with their institutional officials to register with the eRA Commons or ensure their existing eRA Commons account is affiliated with the eRA Commons account of the applicant organization. All registrations must be completed by the application due date. Applicant organizations are strongly encouraged to start the registration process at least four (4) weeks prior to the application due date. Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF 424 (R and R) Application Guide. The Individual currently serving as the Principal Investigator for the Data Coordinating Center may apply for support under this FOA.
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Opportunity Summary:
The grant opportunity "Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)" is a one-time, limited-competition NIH solicitation intended to keep the TEDDY consortium's central Data Coordinating Center (DCC) operating and fully supported. TEDDY is a long-running epidemiological study focused on understanding environmental factors that contribute to diabetes in young people, and the DCC has been involved from the beginning in designing and coordinating the study as well as handling the flow of data and biosamples. This FOA is not seeking multiple new research teams or a broad field of applicants; it is specifically aimed at continuing the established coordinating infrastructure that TEDDY relies on to function smoothly across the consortium.
The mechanism is a cooperative agreement (UC4), which signals that NIH expects substantial involvement and collaboration with the awardee rather than a hands-off grant relationship. Only one award is expected, and the only eligible applicant organization is the institution that employs the current Principal Investigator of the TEDDY Data Coordinating Center. In other words, the competition is intentionally restricted to the existing DCC leadership and home institution, reflecting the need for continuity in procedures, systems, and institutional knowledge that have been built up over the life of the consortium.
The core purpose of the award is operational and infrastructure-focused rather than hypothesis-driven science. The DCC is expected to provide ongoing support for TEDDY study activities for up to five years, with continuation contingent on satisfactory participant recruitment and retention. The required work centers on data and biosample management across the consortium, including standardized acquisition, quality control, and coordinated handling so that information and materials remain consistent, reliable, and usable over time. A major emphasis is also placed on dissemination and public accessibility, meaning the DCC must not only manage the resource internally but also support the creation of a broadly usable, publicly available dataset and associated biosample resource for the wider research community.
A key feature of this FOA is that the DCC must be able to accommodate and support a wide range of research projects that want to use and potentially augment TEDDY data and biosamples. The expectation is that the DCC will provide the systems, documentation, oversight, and logistics that let outside or ancillary projects interface with TEDDY resources without compromising data integrity, participant protections, or study consistency. At the same time, the FOA explicitly states that individual, hypothesis-driven studies are not part of what is being funded here. The deliverable is the coordinated resource itself and the continued execution of analyses already specified in the TEDDY protocol, along with the long-term value of making the resulting data and biosamples available for future, hypothesis-based research by others.
From a funding and administrative standpoint, the FOA (RFA-DK-11-501) was posted April 29, 2011, with an application closing date of June 30, 2011, and an archive date of July 31, 2011. The estimated total funding level is listed as $70,000,000, with an award ceiling of $16,000,000, and there is no cost sharing or matching requirement. The opportunity is categorized under discretionary funding and aligns with health and related public welfare areas. The CFDA numbers listed include 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.865 (Child Health and Human Development Extramural Research), reflecting the cross-cutting nature of TEDDY and its relevance to diabetes and pediatric health; another CFDA number (93.142) is also listed in the source record.
The eligibility and application requirements reflect standard NIH and federal grants compliance steps but are worth highlighting because they are mandatory. The applicant organization must maintain active registrations including a DUNS number (as used at the time), active Central Contractor Registration (CCR) with annual renewal, and registrations with Grants.gov and eRA Commons. The FOA stresses that all registrations must be completed by the due date and recommends starting at least four weeks early to avoid delays. On the investigator side, any individual with the skills and resources to lead may generally serve as PD/PI under NIH rules, and NIH encourages applications from underrepresented groups and individuals with disabilities, but for this specific limited competition the practical eligible PI is the individual currently serving as the TEDDY DCC Principal Investigator because the institution must be that PI's principal employer.
Overall, this opportunity is best understood as continued backbone support for a major longitudinal consortium study, with the DCC serving as the operational hub that keeps data and biosamples standardized, high-quality, secure, and shareable. The goal is to ensure TEDDY continues to generate consistent, analyzable information under its established protocol while also leaving behind a well-curated public resource that can power future research on environmental determinants of diabetes in the young.
FAQs: Limited Competition Data Coordinating Center for the Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)
What is this grant opportunity?
This is a one-time, limited-competition NIH funding opportunity titled "Limited Competition Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4)." Its purpose is to keep the TEDDY consortium's central Data Coordinating Center (DCC) operating and fully supported.
What is TEDDY?
TEDDY is a long-running epidemiological study focused on understanding environmental factors that contribute to diabetes in young people. It is a consortium effort that relies on consistent procedures and coordination across multiple sites and activities.
What is a Data Coordinating Center (DCC) in the context of TEDDY?
The DCC is the operational hub for the TEDDY consortium. It has been involved from the beginning in designing and coordinating the study and managing the flow of consortium data and biosamples so that they remain standardized, high-quality, secure, and usable over time.
What is the funding mechanism and what does "UC4" mean?
The mechanism is a cooperative agreement (UC4). This indicates NIH expects substantial involvement and collaboration with the awardee, rather than a fully hands-off grant relationship.
Is this an open competition?
No. This is intentionally a limited competition. The solicitation is aimed at continuing the established coordinating infrastructure TEDDY relies on, not launching a broad competition among new research teams.
Who is eligible to apply?
Only one organization is eligible: the institution that employs the current Principal Investigator of the TEDDY Data Coordinating Center. The eligibility is restricted to support continuity in procedures, systems, and institutional knowledge built over the life of the consortium.
How many awards will NIH make under this opportunity?
Only one award is expected.
What is the primary purpose of the award?
The award is operational and infrastructure-focused. Its main purpose is to provide ongoing support for TEDDY study activities by maintaining and running the DCC functions that keep the consortium working smoothly.
How long can the DCC be supported under this award?
Support is expected for up to five years, with continuation contingent on satisfactory participant recruitment and retention.
What kinds of activities is the DCC expected to carry out?
The DCC is expected to support consortium-wide data and biosample management, including standardized acquisition, quality control, and coordinated handling so information and materials remain consistent, reliable, and usable over time.
Does this funding support new hypothesis-driven research projects?
No. The FOA explicitly states that individual, hypothesis-driven studies are not part of what is being funded. The deliverable is the coordinated resource itself and the continued execution of analyses already specified in the TEDDY protocol.
What does the FOA emphasize about data sharing and public access?
A major emphasis is dissemination and public accessibility. The DCC is expected to support creation of a broadly usable, publicly available dataset and an associated biosample resource for the wider research community.
How does the DCC relate to outside or ancillary research projects?
The DCC must be able to accommodate and support a wide range of projects that want to use and potentially augment TEDDY data and biosamples. The expectation is that the DCC provides systems, documentation, oversight, and logistics so ancillary projects can interface with TEDDY resources without compromising data integrity, participant protections, or study consistency.
What are the key dates for this FOA?
The FOA (RFA-DK-11-501) was posted April 29, 2011. The application closing date was June 30, 2011. The archive date was July 31, 2011.
How much funding is associated with this opportunity?
The estimated total funding level is listed as $70,000,000, with an award ceiling of $16,000,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What type of funding opportunity category is this?
It is categorized under discretionary funding and aligns with health and related public welfare areas.
Which CFDA numbers are associated with this opportunity?
The CFDA numbers listed include 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and 93.865 (Child Health and Human Development Extramural Research). Another CFDA number (93.142) is also listed in the source record.
What registrations are required to apply?
The FOA highlights standard NIH/federal compliance registrations as mandatory, including a DUNS number (as used at the time), active Central Contractor Registration (CCR) with annual renewal, and registrations with Grants.gov and eRA Commons.
When should registrations be completed?
All registrations must be completed by the application due date. The FOA recommends starting at least four weeks early to avoid delays.
Who can serve as the PD/PI for NIH awards generally, and how does that apply here?
Under NIH rules, any individual with the skills and resources to lead may generally serve as PD/PI, and NIH encourages applications from underrepresented groups and individuals with disabilities. For this specific limited competition, the practical eligible PI is the individual currently serving as the TEDDY DCC Principal Investigator, because the applicant institution must be that PI's principal employer.
Why is the competition restricted to the existing DCC leadership and institution?
The restriction reflects the need for continuity in TEDDY's established procedures, systems, and institutional knowledge. The intent is to keep the coordinating infrastructure fully functioning without disruption.
What is the overall outcome NIH is trying to achieve with this award?
The goal is continued backbone support for a major longitudinal consortium study so TEDDY can keep generating consistent, analyzable information under its established protocol, while also producing a well-curated public dataset and biosample resource that can enable future hypothesis-based research by others.
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