Opportunity Information: Apply for RFA DK 15 509

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Biostatistics Research Center (Collaborative U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jul 20, 2015 and posted on Jul 20, 2015.
  • Applicants must submit their applications by Nov 10, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Native American tribal governments (Federally recognized) State governments Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education County governments Public housing authorities/Indian housing authorities Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The funding opportunity titled "Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Biostatistics Research Center (Collaborative U01)" is a National Institutes of Health (NIH) grant announcement that supports continued long-term research follow-up of adolescents who previously participated in the Teen-LABS study. Teen-LABS is a consortium focused on understanding outcomes of bariatric (weight-loss) surgery performed during adolescence, and this particular announcement is aimed at sustaining the consortiums centralized biostatistics and data coordination functions so investigators can continue tracking participants over time. The main reason for the award is to extend follow-up and preserve the value of the existing cohort by collecting, managing, and analyzing additional longitudinal outcomes data.

This announcement uses a cooperative agreement mechanism (U01), meaning the project is not run as a standard investigator-initiated grant with minimal federal involvement. Instead, NIH is expected to have substantial programmatic involvement, and the awardee works collaboratively with NIH and the Teen-LABS consortium. The scope here centers on the Biostatistics Research Center role within the consortium, which typically includes responsibilities like study-wide statistical leadership, data management and quality control systems, centralized analytic support, harmonizing data collection across clinical sites, maintaining and securing the study database, producing interim and final analyses, and supporting consortium publications. While the clinical follow-up visits and participant-facing activities generally occur at clinical centers, this FOA specifically funds the biostatistics and coordinating backbone that makes multi-site longitudinal follow-up possible and scientifically consistent.

The FOA is explicitly labeled a limited competition. In practical terms, that means NIH is only inviting an application from the existing Biostatistics Research Center for the Teen-LABS consortium rather than opening it up broadly to any applicant who might want to compete. The intent is continuity: keeping the same coordinating infrastructure in place so the consortium can efficiently extend participant follow-up without losing momentum, changing core systems midstream, or introducing methodological discontinuities that can complicate long-term analyses. A companion announcement, RFA-DK-15-508, is referenced as supporting the continuation of the Teen-LABS Clinical Centers, indicating NIH is funding both the participant-facing clinical sites and the centralized biostatistics/coordination center in parallel so the full consortium can continue operating.

From an administrative standpoint, this is a discretionary funding opportunity in the Food and Nutrition and Health activity area, listed under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). NIH anticipated making one award, with an estimated total funding level of about $2,000,000. There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of the award. The original posting date was July 20, 2015, with an application due date of November 10, 2015, and the opportunity archived on December 11, 2015, signaling that it was a time-limited continuation action tied to the Teen-LABS program timeline.

Eligibility is described broadly in the general listing (including state and local governments, tribal governments and organizations, nonprofits, higher education institutions, small businesses, and others), and it also lists a number of specific institution types such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, and faith-based/community-based organizations. However, because the FOA is a limited competition that invites the current Teen-LABS Biostatistics Research Center to apply, those broad eligibility categories function more as standard NIH boilerplate and policy framing than an indication that any eligible entity could realistically apply. The announcement also makes clear that non-U.S. entities are not eligible, non-U.S. components of U.S. organizations are not eligible, and foreign components are not allowed under NIH policy definitions, which is consistent with many NIH cooperative agreements that rely on U.S.-based infrastructure and oversight.

Overall, the opportunity is best understood as a continuation award designed to protect and extend a valuable longitudinal dataset on adolescent bariatric surgery outcomes by funding the centralized statistical and data coordinating hub of the Teen-LABS consortium. The impact of this kind of funding is less about launching a brand-new study and more about ensuring that already-enrolled participants can be followed longer, outcomes can be analyzed rigorously across sites, and the consortium can generate higher-quality evidence on the long-term health effects, risks, and benefits of bariatric procedures performed during adolescence. For reference and full details, NIH provided the archived FOA page at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-509.html, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The opportunity is titled "Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Biostatistics Research Center (Collaborative U01)."

Which agency is offering this grant?

This is a National Institutes of Health (NIH) funding opportunity.

What is the overall purpose of this announcement?

The purpose is to support continued long-term follow-up research of adolescents who previously participated in the Teen-LABS study by sustaining the consortium's centralized biostatistics and data coordination functions.

What is Teen-LABS?

Teen-LABS is a consortium focused on understanding outcomes of bariatric (weight-loss) surgery performed during adolescence. The consortium tracks participants over time to understand longer-term outcomes.

What is being funded under this FOA specifically?

This FOA funds the Biostatistics Research Center role within the Teen-LABS consortium, which serves as the centralized statistical and data coordinating backbone for multi-site longitudinal follow-up.

What kinds of activities are in scope for the Biostatistics Research Center?

Activities typically include study-wide statistical leadership, data management and quality control systems, centralized analytic support, harmonizing data collection across clinical sites, maintaining and securing the study database, producing interim and final analyses, and supporting consortium publications.

Does this FOA fund clinical follow-up visits with participants?

Participant-facing clinical follow-up generally occurs at the clinical centers. This FOA is described as funding the biostatistics and coordinating functions that enable consistent longitudinal follow-up across multiple sites, rather than the clinical visit operations themselves.

What mechanism is used for this award?

The announcement uses a cooperative agreement mechanism (U01).

What does a U01 cooperative agreement imply for how the project is run?

A U01 indicates that NIH is expected to have substantial programmatic involvement. The awardee works collaboratively with NIH and the Teen-LABS consortium rather than operating under a standard investigator-initiated model with minimal federal involvement.

What does "limited competition" mean in this context?

"Limited competition" means NIH is only inviting an application from the existing Teen-LABS Biostatistics Research Center, rather than opening the opportunity broadly to all otherwise-eligible applicants.

Why is this a limited competition rather than an open competition?

The stated intent is continuity: keeping the same coordinating infrastructure in place so the consortium can extend follow-up efficiently without changing core systems midstream or introducing methodological discontinuities that could complicate long-term analyses.

How does this FOA relate to the Teen-LABS Clinical Centers?

A companion announcement, RFA-DK-15-508, is referenced as supporting continuation of the Teen-LABS Clinical Centers. This indicates NIH is funding both the clinical sites and the centralized biostatistics/coordination center in parallel so the consortium can continue operating.

How many awards did NIH anticipate making?

NIH anticipated making one award.

What was the estimated total funding level?

The estimated total funding level was about $2,000,000.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

What is the CFDA number and program area for this opportunity?

The opportunity is listed under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and is described as a discretionary funding opportunity in the Food and Nutrition and Health activity area.

Who is eligible to apply?

The general listing includes many organization types (for example, state and local governments, tribal governments and organizations, nonprofits, higher education institutions, small businesses, and others), and it also lists specific institution types such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, and faith-based/community-based organizations. However, because the FOA is a limited competition, NIH is only inviting the current Teen-LABS Biostatistics Research Center to apply.

Are non-U.S. entities eligible?

No. The announcement states that non-U.S. entities are not eligible, non-U.S. components of U.S. organizations are not eligible, and foreign components are not allowed under NIH policy definitions.

What problem is this FOA trying to address?

The FOA is designed to preserve and extend the value of an existing longitudinal cohort by enabling the collection, management, and analysis of additional long-term outcomes data from participants already enrolled in Teen-LABS.

Is this opportunity intended to launch a brand-new study?

No. It is described as a continuation award focused on extending follow-up and protecting the value of an existing dataset and cohort.

What were the key dates for this opportunity?

The original posting date was July 20, 2015. The application due date was November 10, 2015. The opportunity was archived on December 11, 2015.

What does it mean that the opportunity is archived?

It indicates the announcement was time-limited and is no longer an active solicitation, consistent with a continuation action tied to the Teen-LABS program timeline.

Where can I find the archived FOA page?

NIH provided the archived FOA page at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-509.html.

Where were technical access issues directed?

The notice indicated that technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the FOA.

What is the practical impact of funding a biostatistics and data coordinating center?

The practical impact is enabling scientifically consistent, multi-site long-term follow-up by supporting centralized data systems, quality control, harmonized data collection, and rigorous analyses that help generate stronger evidence on long-term health effects, risks, and benefits of adolescent bariatric surgery.

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Previous opportunity: Limited Competition for the Continuation of Teen LABS (Adolescent Longitudinal Assessment of Bariatric Surgery) Clinical Centers (Collaborative U01)

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